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公开(公告)号:US11435285B2
公开(公告)日:2022-09-06
申请号:US17199312
申请日:2021-03-11
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Evan Thrush , Steven Swihart , William Strong , Trey Marlowe , Li Lu
IPC: G01N21/31 , G01N21/3577 , G01N21/3563
Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.
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公开(公告)号:US09794454B2
公开(公告)日:2017-10-17
申请号:US14789717
申请日:2015-07-01
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Yochanan Uri , Boaz Ran , Itay Barak , Steven Swihart , Evan Thrush
CPC classification number: H04N5/2252 , G01N21/76 , G01N21/763 , G01N2201/0221
Abstract: Provided herein are imaging cassettes for detecting a luminescent and/or radioactive signals. Such cassettes are useful in common biological assays, e.g., immunoassays, nucleotide detection assays, and other affinity assays.
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公开(公告)号:US20140106989A1
公开(公告)日:2014-04-17
申请号:US14056162
申请日:2013-10-17
Inventor: John Barich , Renee Lemaire-Adkins , David Neaz , Ariel Notcovich , Paul Patt , Ryan Short , Steven Swihart , Evan Thrush
IPC: G01N21/63
Abstract: Analyte arrays such as solutes in a slab-shaped gel following electrophoresis, and particularly arrays that are in excess of 3 cm square and up to 25 cm square and higher, are imaged at distances of 5 cm or less by either forming sub-images of the entire array and stitching together the sub-images by computer-based stitching technology, or by using an array of thin-film photoresponsive elements that is coextensive with the analyte array to form a single image of the array.
Abstract translation: 分析物阵列如电泳后的板状凝胶中的溶质,特别是超过3cm见方和高达25cm见方的高达25cm见方的阵列,通过以下方式成像5cm或更小的距离: 整个阵列并通过基于计算机的缝合技术将子图像拼接在一起,或者通过使用与分析物阵列共同延伸以形成阵列的单个图像的薄膜光响应元件阵列来拼接子图像。
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公开(公告)号:US11808697B2
公开(公告)日:2023-11-07
申请号:US17877680
申请日:2022-07-29
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Evan Thrush , Steven Swihart , William Strong , Trey Marlowe , Li Lu
IPC: G01N21/31 , G01N21/3577 , G01N21/3563
CPC classification number: G01N21/3103 , G01N21/3563 , G01N21/3577 , G01N2021/3572 , G01N2201/0686
Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.
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公开(公告)号:US20190107484A1
公开(公告)日:2019-04-11
申请号:US16151732
申请日:2018-10-04
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Evan Thrush , Steven Swihart , William Strong , Trey Marlowe
IPC: G01N21/31 , G01N21/3577 , G01N21/3563
Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.
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公开(公告)号:US20160006910A1
公开(公告)日:2016-01-07
申请号:US14789717
申请日:2015-07-01
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Yochanan Uri , Boaz Ran , Itay Barak , Steven Swihart , Evan Thrush
IPC: H04N5/225
CPC classification number: H04N5/2252 , G01N21/76 , G01N21/763 , G01N2201/0221
Abstract: Provided herein are imaging cassettes for detecting a luminescent and/or radioactive signals. Such cassettes are useful in common biological assays, e.g., immunoassays, nucleotide detection assays, and other affinity assays.
Abstract translation: 本文提供了用于检测发光和/或放射性信号的成像盒。 这样的盒可用于常见的生物测定,例如免疫测定,核苷酸检测测定和其他亲和测定。
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公开(公告)号:US10948403B2
公开(公告)日:2021-03-16
申请号:US16151732
申请日:2018-10-04
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Evan Thrush , Steven Swihart , William Strong , Trey Marlowe , Li Lu
IPC: G01N21/31 , G01N21/3577 , G01N21/3563
Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.
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公开(公告)号:US10788423B2
公开(公告)日:2020-09-29
申请号:US15471264
申请日:2017-03-28
Applicant: Bio-Rad Laboratories, Inc.
Inventor: John Barich , Renee Lemaire-Adkins , David Neaz , Ariel Notcovich , Paul Patt , Ryan Short , Steven Swihart , Evan Thrush , Trey Marlowe
IPC: H04N5/357 , H04N5/361 , G01N21/63 , G01N21/64 , H04N5/262 , H04N5/349 , G01N27/447 , H04N5/335 , G02B21/06
Abstract: Analyte arrays such as solutes in a slab-shaped gel following electrophoresis, and particularly arrays that are in excess of 3 cm square and up to 25 cm square and higher, are imaged at distances of 5 cm or less by either forming sub-images of the entire array and stitching together the sub-images by computer-based stitching technology, or by using an array of thin-film photoresponsive elements that is coextensive with the analyte array to form a single image of the array.
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公开(公告)号:US10564098B2
公开(公告)日:2020-02-18
申请号:US14056162
申请日:2013-10-17
Applicant: Bio-Rad Laboratories, Inc.
Inventor: John Barich , Renee Lemaire-Adkins , David Neaz , Ariel Notcovich , Paul Patt , Ryan Short , Steven Swihart , Evan Thrush , Trey Marlowe
IPC: H04N5/361 , H04N5/357 , H04N5/335 , G01N21/64 , G01N21/63 , H04N5/262 , H04N5/349 , G01N27/447 , G02B21/06
Abstract: Analyte arrays such as solutes in a slab-shaped gel following electrophoresis, and particularly arrays that are in excess of 3 cm square and up to 25 cm square and higher, are imaged at distances of 5 cm or less by either forming sub-images of the entire array and stitching together the sub-images by computer-based stitching technology, or by using an array of thin-film photoresponsive elements that is coextensive with the analyte array to form a single image of the array.
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