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公开(公告)号：US20240150308A1
公开(公告)日：2024-05-09
申请号：US18532307
申请日：2023-12-07
Applicant: CHIROGATE INTERNATIONAL INC.
Inventor： CHUN-YU LIN , TZYH-MANN WEI , SHIH-YI WEI
IPC: C07D307/93 , C07C45/65 , C07C49/573 , C07C67/24 , C07C67/317 , C07C69/157 , C07C69/734 , C07D307/42 , C07F7/18 , C12P7/38
CPC classification number: C07D307/93 , C07C45/65 , C07C49/573 , C07C67/24 , C07C67/317 , C07C69/157 , C07C69/734 , C07D307/42 , C07F7/1892 , C12P7/38 , C07C2601/08 , C07C2601/10 , C07C2601/16
Abstract: The invention relates to processes for preparing benzoprostacyclin analogues and intermediates prepared from the process, and the benzoprostacyclin analogues prepared therefrom. The invention also relates to cyclopentenone intermediates in racemic or optically active form.
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公开(公告)号：US20230416216A1
公开(公告)日：2023-12-28
申请号：US18467441
申请日：2023-09-14
Applicant: CHIROGATE INTERNATIONAL INC.
Inventor： CHUN-YU LIN , TZYH-MANN WEI , SHIH-YI WEI
IPC: C07D307/93 , C07C45/65 , C07C49/573 , C07C67/24 , C07C67/317 , C07C69/157 , C07C69/734 , C07D307/42 , C07F7/18 , C12P7/38
CPC classification number: C07D307/93 , C07C45/65 , C07C49/573 , C07C67/24 , C07C67/317 , C07C69/157 , C07C69/734 , C07D307/42 , C07F7/1892 , C12P7/38 , C07C2601/08 , C07C2601/10 , C07C2601/16
Abstract: A racemic or optically enriched compound of Formula 1:
wherein P is H or a protective group for hydroxyl groups; and X is Cl, Br, I, or —CH2CH2CH2COOR1, wherein R1 is C1-7-alkyl or C7-11-aralkyl.-
公开(公告)号：US20230357119A1
公开(公告)日：2023-11-09
申请号：US18325214
申请日：2023-05-30
Applicant: CHIROGATE INTERNATIONAL INC.
Inventor： CHUN-YU LIN , TZYH-MANN WEI , SHIH-YI WEI
IPC: C07C49/743 , C07C59/62 , C07C33/12 , C12P7/62 , C12P7/38 , C07D307/42
CPC classification number: C07C49/743 , C07C33/12 , C07C59/62 , C07D307/42 , C12P7/38 , C12P7/62
Abstract: The invention relates to processes for preparing carbaprostacyclin analogues and intermediates prepared from the processes. The invention also relates to cyclopentenone intermediates in racemic or optically active form.
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Patent Agency Ranking
公开(公告)号：US20230357118A1
公开(公告)日：2023-11-09
申请号：US17737273
申请日：2022-05-05
Applicant: CHIROGATE INTERNATIONAL INC.
Inventor： CHUN-YU LIN , TZYH-MANN WEI , SHIH-YI WEI
IPC: C07C49/743 , C12P7/38 , C12P7/62 , C07D307/42 , C07C59/62 , C07C33/12
CPC classification number: C07C49/743 , C12P7/38 , C12P7/62 , C07D307/42 , C07C59/62 , C07C33/12
Abstract: The invention relates to processes for preparing carbaprostacyclin analogues and intermediates prepared from the processes. The invention also relates to cyclopentenone intermediates in racemic or optically active form.
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公开(公告)号：US20240025832A1
公开(公告)日：2024-01-25
申请号：US18476137
申请日：2023-09-27
Applicant: CHIROGATE INTERNATIONAL INC.
Inventor： CHUN-YU LIN , TZYH-MANN WEI , SHIH-YI WEI
IPC: C07C49/743 , C07C33/12 , C12P7/62 , C07C59/62 , C12P7/38 , C07D307/42
CPC classification number: C07C49/743 , C07C33/12 , C12P7/62 , C07C59/62 , C12P7/38 , C07D307/42
Abstract: The invention relates to processes for preparing carbaprostacyclin analogues and intermediates prepared from the processes. The invention also relates to cyclopentenone intermediates in racemic or optically active form.
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公开(公告)号：US20230002339A1
公开(公告)日：2023-01-05
申请号：US17336865
申请日：2021-06-02
Applicant: CHIROGATE INTERNATIONAL INC.
Inventor： CHUN-YU LIN , TZYH-MANN WEI , SHIH-YI WEI
IPC: C07D307/93 , C07F7/18 , C07C67/317 , C07C69/734 , C07C49/573 , C07C45/65 , C07C67/24 , C07C69/157 , C07D307/42 , C12P7/38
Abstract: The invention relates to processes for preparing benzoprostacyclin analogues and intermediates prepared from the process, and the benzoprostacyclin analogues prepared therefrom. The invention also relates to cyclopentenone intermediates in racemic or optically active form.
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公开(公告)号：US20220024849A1
公开(公告)日：2022-01-27
申请号：US16938238
申请日：2020-07-24
Applicant: CHIROGATE INTERNATIONAL INC.
Inventor： SHIH-YI WEI , MING-KUN HSU , TZYH-MANN WEI
IPC: C07C201/02
Abstract: Processes for preparing latanoprostene bunod and an intermediate prepared from the process. Also latanoprostene bunod compositions having high-purity latanoprostene bunod.
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公开(公告)号：US20210188757A1
公开(公告)日：2021-06-24
申请号：US16720711
申请日：2019-12-19
Applicant: CHIROGATE INTERNATIONAL INC.
Inventor： SHIH-YI WEI , JIAN-BANG JHENG , MING-KUN HSU , MIN-KUAN HSU , TZYH-MANN WEI
Abstract: There is provided a crystalline Form I of anhydrous Treprostinil and processes for the preparation thereof. The crystalline Form I of anhydrous Treprostnil is a stable crystalline form, which can provide steady physicochemical properties for pharmaceutical formulations, and is advantageous widely and safety used in storage, shipment, and handling for commercially considerations.
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