公开(公告)号：US09993414B2

公开(公告)日：2018-06-12

申请号：US14652785

申请日：2012-12-17

Applicant: Colgate-Palmolive Company

Inventor： Zhigang Hao ,  Ying Yang ,  Zhiqiang Liu ,  Katherine Hu ,  Guofeng Xu ,  Paul Joseph Vincenti

IPC: A61K8/60 ,  A61Q11/00 ,  A61K8/44

CPC classification number: A61K8/60 ,  A61K2800/92 ,  A61Q11/00

Abstract: The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject.

公开(公告)号：US20150328120A1

公开(公告)日：2015-11-19

申请号：US14652785

申请日：2012-12-17

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Zhigang Hao ,  Ying Yang ,  Zhiqiang Liu ,  Katherine Hu ,  Guofeng Xu ,  Paul Joseph Vincenti

IPC: A61K8/60 ,  A61Q11/00

CPC classification number: A61K8/60 ,  A61K2800/92 ,  A61Q11/00

Abstract: The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject.

Abstract translation: 本发明涉及口腔护理组合物和抑制微生物生物膜形成和/或降解微生物生物膜的方法。 本文公开了包含具有葡萄糖部分和氨基酸部分的阿马多里化合物的口腔护理组合物。 阿马多利化合物可用于抑制口腔微生物生物膜形成和/或降解哺乳动物受试者口腔中的口腔微生物生物膜。