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公开(公告)号：US11197811B2
公开(公告)日：2021-12-14
申请号：US16798492
申请日：2020-02-24
发明人： Zhiqiang Liu , Long Pan , Shaotang Yuan , Jairajh Mattai , James Masters
摘要： Described herein are methods of cleaning a tooth comprising administering a composition comprising a zinc amino acid halide complex to the oral cavity; and retaining the composition in the oral cavity for a time sufficient to form a precipitate.
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2.发明授权Teeth whitening methods, visually perceptible signals and compositions therefor 有权牙齿美白方法，视觉上可察觉的信号和组合物公开(公告)号：US09572756B2
公开(公告)日：2017-02-21
申请号：US14653300
申请日：2012-12-19
发明人： Zhiqiang Liu , Long Pan , Shaotang Yuan , Jairajh Mattai , James G. Masters
CPC分类号： A61K8/44 , A61K8/0216 , A61K8/20 , A61K8/27 , A61K2800/45 , A61K2800/58 , A61Q11/00
摘要： Described herein are methods of cleaning a tooth comprising administering a composition comprising a zinc amino acid halide complex to the oral cavity; and retaining the composition in the oral cavity for a time sufficient to form a precipitate.
摘要翻译： 本文描述了清洁牙齿的方法，包括向口腔施用包含锌氨基酰卤配合物的组合物; 并将组合物保持在口腔中足以形成沉淀物的时间。
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3.发明申请ORAL CARE PRODUCTS COMPRISING A TETRABASIC ZINC-AMINO ACID-HALIDE COMPLEX 有权口服保健产品，包含一种四乙酰胺 - 氨基酸 - 卤化物复合物公开(公告)号：US20150328111A1
公开(公告)日：2015-11-19
申请号：US14653882
申请日：2012-12-19
发明人： Zhiqiang Liu , Long Pan , Ying Yang , Guofeng Xu , Michael A. Stranick
CPC分类号： A61K8/27 , A61K8/20 , A61K8/21 , A61K8/44 , A61K2800/58 , A61K2800/92 , A61Q11/00
摘要： Described herein are oral care compositions comprising a tetrabasic zinc halide and an amino acid; along with methods of making and using the same.
摘要翻译： 本文描述的是包含四元卤化锌和氨基酸的口腔护理组合物; 以及制作和使用方法。
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公开(公告)号：US10524995B2
公开(公告)日：2020-01-07
申请号：US15964193
申请日：2018-04-27
发明人： Long Pan , Shaotang Yuan , Shira Pilch , James Masters , Zhiqiang Liu
摘要： Disclosed herein are mouthwashes comprising a complex of a zinc ion source and an amino acid. Methods of making and using the compositions are also provided.
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公开(公告)号：US09775792B2
公开(公告)日：2017-10-03
申请号：US14653882
申请日：2012-12-19
发明人： Zhiqiang Liu , Long Pan , Ying Yang , Guofeng Xu , Michael A. Stranick
CPC分类号： A61K8/27 , A61K8/20 , A61K8/21 , A61K8/44 , A61K2800/58 , A61K2800/92 , A61Q11/00
摘要： Described herein are oral care compositions comprising a tetrabasic zinc halide and an amino acid; along with methods of making and using the same.
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公开(公告)号：US20160008254A1
公开(公告)日：2016-01-14
申请号：US14652780
申请日：2012-12-19
发明人： Zhigang Hao , Ying Yang , Zhiqiang Liu , Xu Guofeng , Paul Joseph Vincenti
摘要： Provided herein is an oral care composition comprising an orally-acceptable aqueous vehicle and an antimicrobial ingredient, wherein the antimicrobial ingredient comprises a zinc ascorbylphosphate and methods for treating or preventing a disease or disorder of the oral cavity using the oral care compositions disclosed herein.
摘要翻译： 本文提供了包含口服可接受的水性载体和抗微生物成分的口腔护理组合物，其中所述抗微生物成分包含抗坏血酸磷酸锌和使用本文公开的口腔护理组合物治疗或预防口腔疾病或病症的方法。
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7.发明申请TWO COMPONENT COMPOSITIONS CONTAINING ZINC AMINO ACID HALIDE COMPLEXES AND CYSTEINE 有权含有ZINC氨基酸卤化物复合物和CYSTEINE的两种组分公开(公告)号：US20150342851A1
公开(公告)日：2015-12-03
申请号：US14653896
申请日：2013-11-07
发明人： Zhiqiang Liu , Long Pan , Joseph Convery , Shaotang Yuan , Harsh M. Trivedi
CPC分类号： A61Q11/00 , A61K8/20 , A61K8/27 , A61K8/44 , A61K8/46 , A61K2800/58 , A61K2800/882 , A61Q15/00 , A61Q19/10
摘要： Provided are compositions, e.g., oral and personal care products, comprising (i) a zinc (amino acid or trialkyl glycine) halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.
摘要翻译： 提供的是组合物，例如口服和个人护理产品，其包含（i）锌（氨基酸或三烷基甘氨酸）卤化物配合物，和（ii）游离或口服或化妆品可接受的盐形式的半胱氨酸，以及制备和 使用相同
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公开(公告)号：US09993407B2
公开(公告)日：2018-06-12
申请号：US15411144
申请日：2017-01-20
发明人： Zhiqiang Liu , Long Pan , Shaotang Yuan , Jairajh Mattai , James G. Masters
CPC分类号： A61K8/44 , A61K8/0216 , A61K8/20 , A61K8/27 , A61K2800/45 , A61K2800/58 , A61Q11/00
摘要： Described herein are methods of cleaning a tooth comprising administering a composition comprising a zinc amino acid halide complex to the oral cavity; and retaining the composition in the oral cavity for a time sufficient to form a precipitate.
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公开(公告)号：US09861563B2
公开(公告)日：2018-01-09
申请号：US14653876
申请日：2012-12-19
发明人： LaTonya Kilpatrick-Liverman , Zhiqiang Liu , Long Pan , Ying Yang , Guofeng Xu , Michael A. Stranick , Zhigang Hao
CPC分类号： A61K8/27 , A61K8/21 , A61K8/416 , A61K8/44 , A61K2800/74 , A61Q11/00 , C07C229/12
摘要： The invention provides oral care compositions comprising a mixture of tetrabasic zinc halide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
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公开(公告)号：US09763865B2
公开(公告)日：2017-09-19
申请号：US14653880
申请日：2012-12-19
发明人： Long Pan , Shaotang Yuan , Shira Pilch , James G. Masters , Zhiqiang Liu , Vyoma Patel
CPC分类号： A61K8/44 , A61K8/042 , A61K8/20 , A61K8/21 , A61K8/27 , A61K8/442 , A61K8/731 , A61K2800/58 , A61K2800/92 , A61Q11/00
摘要： Disclosed herein are dentifrices comprising a zinc amino acid halide, which provide a precipitate of zinc oxide upon use with dilution with water and/or saliva. Methods of making and using the dentifrices are also provided.
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