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公开(公告)号:US20250057740A1
公开(公告)日:2025-02-20
申请号:US18917373
申请日:2024-10-16
Applicant: Colgate-Palmolive Company
Inventor: Carl MYERS , Iraklis Pappas , Zhigang Hao , Saide Tang
Abstract: Disclosed herein are high water oral care compositions comprising a stannous ion source. which compositions have improved stability. Methods of making and using the compositions are also provided.
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公开(公告)号:US20240277583A1
公开(公告)日:2024-08-22
申请号:US18512294
申请日:2023-11-17
Applicant: Colgate-Palmolive Company
Inventor: Changlong CHEN , Chi-Yuan Cheng , Hongwei Shen , Zhigang Hao , Svenia Schmid , Thomas Schollbach , Cornelia Scheffel
CPC classification number: A61K8/0291 , A61K8/41 , A61Q11/00 , A61K2800/30 , A61K2800/92
Abstract: The present disclosure relates to a mouthwash composition containing an amine fluoride or amine base plus fluoride and an alkyl glucoside, as well as related methods for use of said compositions.
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公开(公告)号:US20210275416A1
公开(公告)日:2021-09-09
申请号:US17249523
申请日:2021-03-04
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Chi-Yuan Cheng , Tatiana Brinzari , Long Pan , Ravi Subramanyam
Abstract: The disclosure provides a zinc-arginine complex, methods of making the same, and methods of using the same in oral care compositions.
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公开(公告)号:US10052045B2
公开(公告)日:2018-08-21
申请号:US14441184
申请日:2012-12-21
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid
CPC classification number: A61B5/08 , A61B5/082 , A61B10/00 , A61B2010/0087 , A61K8/33 , A61K8/35 , A61K8/55 , A61Q11/00 , G01N33/497 , G01N2033/4975 , Y10T436/182
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
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公开(公告)号:US12161743B2
公开(公告)日:2024-12-10
申请号:US17695100
申请日:2022-03-15
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Chi-Yuan Cheng , Long Pan , Ravi Subramanyam
Abstract: The present disclosure provides a chlorhexidine-cyclamate complex having a formula [C22H32Cl2N10][C6H12NO3S]2 having antibacterial and antiplaque properties, together with oral care compositions comprising the complex, and methods of making and using these complexes and compositions.
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公开(公告)号:US11892435B2
公开(公告)日:2024-02-06
申请号:US16703985
申请日:2019-12-05
Applicant: Colgate-Palmolive Company
Inventor: Chi-Yuan Cheng , Zhigang Hao , Long Pan , Zolijargal Balsandorj
IPC: G01N33/15 , G01N24/08 , G01N31/22 , G01R33/465
CPC classification number: G01N31/221 , G01N24/08 , G01R33/465
Abstract: Methods for measuring pH of gel, paste, colloid, and aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, are provided. The method may include preparing a calibration curve of a chemical species including or having an acid dissociation constant. Preparing the calibration curve may include plotting a chemical shift of the chemical species relative to pH. The method may also include determining a chemical shift of a gel, paste, and colloid, aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, including the chemical species. The method may further include determining the pH of the gel, paste, colloid, and aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, with the chemical shift of the product and the calibration curve.
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公开(公告)号:US11065186B2
公开(公告)日:2021-07-20
申请号:US16267424
申请日:2019-02-05
Applicant: Colgate-Palmolive Company
Inventor: Shiri Nawrocki , Viktor Dubovoy , Long Pan , Zhigang Hao , Nihal Dogu
Abstract: Provided are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt, e.g., sodium tripolyphosphate (Na5P3O10), and oral care compositions comprising the complex and uses thereof.
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公开(公告)号:US10532016B2
公开(公告)日:2020-01-14
申请号:US16213871
申请日:2018-12-07
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Dennis Zhang , Donghui Wu , Ravi Subramanyam , Chi-Yuan Cheng , Long Pan , Stanislav Jaracz
Abstract: Disclosed herein are zinc-amino acid-tripolyphosphate complexes, oral care and personal care compositions comprising zinc-amino acid-tripolyphosphate complexes, and methods of making and using the same.
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公开(公告)号:US20160008254A1
公开(公告)日:2016-01-14
申请号:US14652780
申请日:2012-12-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: Zhigang Hao , Ying Yang , Zhiqiang Liu , Xu Guofeng , Paul Joseph Vincenti
CPC classification number: A61K8/58 , A61K8/27 , A61K8/55 , A61K8/676 , A61K33/30 , A61K2800/58 , A61Q11/00
Abstract: Provided herein is an oral care composition comprising an orally-acceptable aqueous vehicle and an antimicrobial ingredient, wherein the antimicrobial ingredient comprises a zinc ascorbylphosphate and methods for treating or preventing a disease or disorder of the oral cavity using the oral care compositions disclosed herein.
Abstract translation: 本文提供了包含口服可接受的水性载体和抗微生物成分的口腔护理组合物,其中所述抗微生物成分包含抗坏血酸磷酸锌和使用本文公开的口腔护理组合物治疗或预防口腔疾病或病症的方法。
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公开(公告)号:US11826448B2
公开(公告)日:2023-11-28
申请号:US17249523
申请日:2021-03-04
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Chi-Yuan Cheng , Tatiana Brinzari , Long Pan , Ravi Subramanyam
Abstract: The disclosure provides a zinc-arginine complex, methods of making the same, and methods of using the same in oral care compositions.
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