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    Preservative System
    3.
    发明申请
    Preservative System 审中-公开
    防腐系统

    公开(公告)号：US20160262997A1

    公开(公告)日：2016-09-15

    申请号：US15035648

    申请日：2013-11-11

    Applicant: Colgate-Palmolive Company

    Inventor： Catherine Lewus ,  Laurence D. Du-Thumm ,  Rehana Begum-Gafur ,  Kimdra Smith-Webster ,  Mark Vandeven

    IPC: A61K8/368 ,  A61Q19/10

    CPC classification number: A61K8/368 ,  A61K2800/524 ,  A61K2800/5922 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q19/10

    Abstract: Provided herein is a cost-effective and potent preservative system for a composition comprising a salicylate salt and a benzoate salt in an amount of from 0.2 weight % to 0.5 weight % by total weight of the composition and in a molar ratio of salicylate to benzoate of 1:6 to 1:1.2, wherein the composition has a pH of 5 or less. Further provided herein is a method of using a combination of a salicylate salt and a benzoate salt in a preservative system in a composition, and a method of preserving a composition.

    Abstract translation: 本文提供了一种用于组合物的成本有效和有效的防腐剂体系，其包含水杨酸盐和苯甲酸盐，其量为组合物总重量的0.2重量％至0.5重量％，水杨酸盐与苯甲酸酯的摩尔比为 1：6〜1：1.2，其中，所述组合物的pH为5以下。 本文还提供了在组合物中在防腐剂体系中使用水杨酸盐和苯甲酸盐的组合的方法以及保存组合物的方法。

    Oral Care Composition Containing Ionic Liquids
    4.
    发明申请
    Oral Care Composition Containing Ionic Liquids 有权
    含有离子液体的口腔护理组合物

    公开(公告)号：US20150335549A1

    公开(公告)日：2015-11-26

    申请号：US14654417

    申请日：2012-12-20

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： Madhusudan Patel ,  Guillaume Picquet ,  Mark Vandeven ,  Mahmoud Hassan ,  Rosa Paredes

    IPC: A61K8/41 ,  A61K8/49 ,  A61Q11/00 ,  A61K8/368 ,  A61K8/46

    CPC classification number: A61K8/416 ,  A61K8/368 ,  A61K8/466 ,  A61K8/4926 ,  A61K31/095 ,  A61K31/14 ,  A61K31/60 ,  A61K45/06 ,  A61K2800/30 ,  A61Q11/00 ,  A61K2300/00

    Abstract: An oral care composition is provided wherein the composition comprises an ionic liquid, wherein the ionic liquid comprises: a) a quaternary ammonium cation of the formula wherein R1, R2, R3 and R4 are each an organic moiety and may be the same or different, and at least one of R1, R2, R3 and R4 includes a hydroxyl; and b) an anion selected from the group consisting of salicylate, alkylsulfate, sulfate, acetate, halide, phosphate, alkyl phosphate and tosylate; wherein the oral care composition is a mouth rinse, toothpaste, toothpowder, oral bead or strip, fluid-encased dental strip, irrigation fluid, plaque removal liquid, dental floss, hard candy, soft candy, lozenge, chewing gum, or lollipop.

    Abstract translation: 提供一种口腔护理组合物，其中所述组合物包含离子液体，其中所述离子液体包含：a）下式的季铵阳离子其中R 1，R 2，R 3和R 4各自为有机部分，并且可以相同或不同， 并且R 1，R 2，R 3和R 4中的至少一个包括羟基; 和b）选自水杨酸盐，烷基硫酸盐，硫酸盐，乙酸盐，卤化物，磷酸盐，磷酸烷基酯和甲苯磺酸盐的阴离子; 其中所述口腔护理组合物是口腔清洁剂，牙膏，牙粉，口腔珠或条，流体包裹的牙带，冲洗液，牙斑去除液，牙线，硬糖，软糖，锭剂，口香糖或棒棒糖。

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