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公开(公告)号：US10918588B2
公开(公告)日：2021-02-16
申请号：US14441782
申请日：2013-11-08
Applicant: COLGATE-PALMOLIVE COMPANY , HOWARD UNIVERSITY
Inventor： Tongxin Wang , Yanda Lei , James W. Mitchell , Lynette Zaidel , Jian-hong Qiu , Mahmoud Hassan
Abstract: Described herein are block copolymers having hydrophobic blocks and hydrophilic blocks which are effective in binding to the surface of hard tissue; compositions comprising the same, as well as methods of making and using the same.
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公开(公告)号：US20170172864A1
公开(公告)日：2017-06-22
申请号：US14974723
申请日：2015-12-18
Applicant: Colgate-Palmolive Company
Inventor： Lauren Evans , Mahmoud Hassan
CPC classification number: A61K8/22 , A61K8/19 , A61K8/8176 , A61K8/891 , A61K2800/592 , A61K2800/594 , A61Q11/00 , A61Q11/02
Abstract: Disclosed herein are tooth whitening compositions comprising a peroxide complex comprising hydrogen peroxide and an N-vinyl heterocyclic polymer; sodium percarbonate; and at least one hydrophobic polymer carrier, wherein the hydrogen peroxide of the peroxide complex is present in the tooth whitening composition in an amount ranging from about 3% to about 5% by weight. Further disclosed herein are methods for whitening a surface of a tooth comprising applying a tooth whitening composition as disclosed herein and methods for making a tooth whitening composition.
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公开(公告)号：US20160338931A1
公开(公告)日：2016-11-24
申请号：US15106478
申请日：2014-10-23
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Shao Peng Xu , Wei Song , Xiong Fei Qin , Yuan Hui Xie , Mahmoud Hassan
CPC classification number: A61K8/602 , A61K8/345 , A61K2800/92 , A61Q11/00
Abstract: The present invention generally relates to oral care compositions which enhance the solubility of rutin comprising rutin and at least one polyhydroxyalkyl alcohol. The present invention also relates to methods for use and manufacturing said oral care compositions.
Abstract translation: 本发明一般涉及提高含芦丁和至少一种多羟基烷基醇的芦丁的溶解度的口腔护理组合物。 本发明还涉及使用和制造所述口腔护理组合物的方法。
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公开(公告)号：US20150335549A1
公开(公告)日：2015-11-26
申请号：US14654417
申请日：2012-12-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Madhusudan Patel , Guillaume Picquet , Mark Vandeven , Mahmoud Hassan , Rosa Paredes
CPC classification number: A61K8/416 , A61K8/368 , A61K8/466 , A61K8/4926 , A61K31/095 , A61K31/14 , A61K31/60 , A61K45/06 , A61K2800/30 , A61Q11/00 , A61K2300/00
Abstract: An oral care composition is provided wherein the composition comprises an ionic liquid, wherein the ionic liquid comprises: a) a quaternary ammonium cation of the formula wherein R1, R2, R3 and R4 are each an organic moiety and may be the same or different, and at least one of R1, R2, R3 and R4 includes a hydroxyl; and b) an anion selected from the group consisting of salicylate, alkylsulfate, sulfate, acetate, halide, phosphate, alkyl phosphate and tosylate; wherein the oral care composition is a mouth rinse, toothpaste, toothpowder, oral bead or strip, fluid-encased dental strip, irrigation fluid, plaque removal liquid, dental floss, hard candy, soft candy, lozenge, chewing gum, or lollipop.
Abstract translation: 提供一种口腔护理组合物，其中所述组合物包含离子液体，其中所述离子液体包含：a）下式的季铵阳离子其中R 1，R 2，R 3和R 4各自为有机部分，并且可以相同或不同， 并且R 1，R 2，R 3和R 4中的至少一个包括羟基; 和b）选自水杨酸盐，烷基硫酸盐，硫酸盐，乙酸盐，卤化物，磷酸盐，磷酸烷基酯和甲苯磺酸盐的阴离子; 其中所述口腔护理组合物是口腔清洁剂，牙膏，牙粉，口腔珠或条，流体包裹的牙带，冲洗液，牙斑去除液，牙线，硬糖，软糖，锭剂，口香糖或棒棒糖。
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公开(公告)号：US20140134116A1
公开(公告)日：2014-05-15
申请号：US14075230
申请日：2013-11-08
Applicant: Colgate-Palmolive Company , Howard University
Inventor： Tongxin Wang , Yanda Lei , James W. Mitchell , Lynette Zaidel , Jianhong Qiu , Mahmoud Hassan
CPC classification number: A61K8/90 , A61K8/21 , A61Q11/00 , C08F293/005
Abstract: Described herein are block copolymers having hydrophobic blocks and hydrophilic blocks which are effective in binding to the surface of hard tissue; compositions comprising the same, as well as methods of making and using the same are also described.
Abstract translation: 这里描述的是具有疏水性嵌段和亲水性嵌段的嵌段共聚物，该嵌段共聚物有效结合硬组织的表面; 还描述了包含它们的组合物，以及制备和使用它们的方法。
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Patent Agency Ranking
公开(公告)号：US11376206B2
公开(公告)日：2022-07-05
申请号：US15840046
申请日：2017-12-13
Applicant: Colgate-Palmolive Company
Inventor： Mahmoud Hassan , Xiang Chen , Shyamala Pillai , Guofeng Xu , LaTonya Kilpatrick-Liverman , Suman Chopra , Robert Dicosimo , Mark S. Payne
IPC: A61K8/66 , A61Q11/00 , A61K8/22 , A61K8/81 , A61K8/06 , A61C19/06 , A61K8/37 , A61K8/44 , A61K8/31 , A61K8/49
Abstract: A two-phase oral care whitening composition including a hydrophobic phase and a hydrophilic phase, and methods for oral care whitening teeth with the same are provided. The hydrophobic phase may include a source of hydrogen peroxide and an acyl donor. The hydrophilic phase may include an enzyme that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor. At least one of the hydrophobic phase and the hydrophilic phase may further include at least one surfactant.
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公开(公告)号：US11304889B2
公开(公告)日：2022-04-19
申请号：US15840050
申请日：2017-12-13
Applicant: Colgate-Palmolive Company
Inventor： Shyamala Pillai , Guofeng Xu , LaTonya Kilpatrick-Liverman , Xiang Chen , Suman Chopra , Robert Dicosimo , Mark S. Payne , Mahmoud Hassan
IPC: A61K8/66 , A61K8/46 , A61K8/37 , A61Q11/00 , A61K8/22 , A61K8/81 , A61K8/06 , A61C19/06 , A61K8/44 , A61K8/31 , A61K8/49
Abstract: An oral care composition including a hydrophobic phase and a hydrophilic phase is disclosed. The hydrophobic phase may include a source of hydrogen peroxide and an acyl donor, and the hydrophilic phase may include an enzyme having perhydrolytic activity that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor.
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公开(公告)号：US10251823B2
公开(公告)日：2019-04-09
申请号：US15525381
申请日：2015-11-13
Applicant: Colgate-Palmolive Company
Inventor： Ravi Subramanyam , Suzanne Jogun , Mahmoud Hassan , Navin Lewis , Xiao Yi Huang , Shao Peng Xu
IPC: A61K8/27 , A61K8/25 , A61K8/365 , A61Q11/00 , A61K8/02 , A61K8/04 , A61K8/19 , A61K8/21 , A61K8/37
Abstract: The present invention provides an oral care composition comprising: (a) a first composition comprising a silica abrasive and a first zinc compound selected from zinc citrate, zinc chloride, zinc acetate, zinc lactate, zinc salicylate, zinc sulfate, and zinc nitrate; and (b) a second composition comprising a calcium carbonate abrasive; wherein the first composition and/or the second composition further comprises a second zinc compound selected from zinc oxide, zinc carbonate and zinc tartrate; and wherein the oral care composition optionally further comprises from 0.1 to 1.75 weight % of a tartar control agent, based on the total weight of the oral care composition.
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公开(公告)号：US20160051833A1
公开(公告)日：2016-02-25
申请号：US14931741
申请日：2015-11-03
Applicant: Colgate-Palmolive Company
Inventor： Madhusudan Patel , Rosa Paredes , Mahmoud Hassan , Thomas Boyd
IPC: A61N5/06 , A61K31/655
CPC classification number: A61N5/062 , A61K8/0208 , A61K8/35 , A61K8/466 , A61K8/494 , A61K31/655 , A61K2800/434 , A61K2800/81 , A61K2800/88 , A61N5/0601 , A61N5/0603 , A61N5/0624 , A61N2005/0606 , A61N2005/0659 , A61N2005/0661 , A61N2005/0662 , A61N2005/0663 , A61Q11/00 , A61Q17/005
Abstract: Generally regarded as safe (GRAS) dyes can be used as photosensitizing dyes in oral compositions to provide anti-bacterial and anti-inflammatory efficacy. Embodiments include oral care compositions including photosensitizing dyes, methods of making the compositions, methods of using the compositions, and kits containing the compositions and light emitting devices.
Abstract translation: 通常认为安全（GRAS）染料可用作口腔组合物中的光敏染料，以提供抗细菌和抗炎功效。 实施方案包括口腔护理组合物，包括光敏染料，制备组合物的方法，使用该组合物的方法，以及含有组合物和发光装置的试剂盒。
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公开(公告)号：US20150335548A1
公开(公告)日：2015-11-26
申请号：US14654380
申请日：2012-12-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Madhusudan Patel , Mahmoud Hassan
CPC classification number: A61K8/416 , A61K8/20 , A61K8/368 , A61K8/466 , A61K8/494 , A61K8/4946 , A61K31/415 , A61K31/4164 , A61K2800/30 , A61Q11/00
Abstract: An oral care composition is provided which comprises a therapeutically effective amount of at least one ionic liquid for use in removing or reducing plaque, inhibiting the amount of bacteria in an oral cavity, inhibiting biofilm formation and/or degradation in an oral cavity and teeth whitening.
Abstract translation: 提供一种口腔护理组合物，其包含治疗有效量的至少一种用于去除或减少斑块的离子液体，抑制口腔中的细菌数量，抑制口腔中的生物膜形成和/或降解以及牙齿美白 。
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