公开(公告)号：US20150183639A1

公开(公告)日：2015-07-02

申请号：US14643878

申请日：2015-03-10

Applicant: COSKATA, INC.

Inventor： Richard E. Tobey

IPC: C01B3/52

CPC classification number: C01B3/52 ,  B01D53/00 ,  C01B2203/04 ,  C01B2203/0415 ,  C01B2203/043 ,  C01B2203/0465 ,  C01B2203/0475 ,  C01B2203/048 ,  C01B2203/0485 ,  C01B2203/0495 ,  C01B2203/061 ,  C01B2203/062 ,  C01B2203/146 ,  C12M47/18

Abstract: This invention pertains to processes for selectively oxidizing hydrogen cyanide contained in syngas using permanganate anion as an oxidant contained in an aqueous solution that is contacted with the syngas under certain conditions of temperature, pressure and duration of contact.

Abstract translation: 本发明涉及使用高锰酸盐阴离子作为氧化剂选择性地氧化合成气中所含的氰化氢的方法，所述氧化剂包含在与合成气接触的水溶液中，在某些温度，压力和接触时间条件下。

公开(公告)号：US20140220649A1

公开(公告)日：2014-08-07

申请号：US14245907

申请日：2014-04-04

Applicant: COSKATA, INC.

Inventor： Richard E. Tobey ,  Toby D. Allen ,  Peter Martin Lokken ,  Andrew James Heinen ,  Gengsheng Chen

IPC: C12P7/16

CPC classification number: C12P7/16 ,  C12P7/40 ,  Y02E50/10

Abstract: The invention relates to improvements in the production of butanol and butyrate by microbial fermentation, particularly to production of alcohols by microbial fermentation of a substrate comprising CO and the addition of an inorganic sulfur additive. It more particularly relates to the provision of an inorganic organic sulfur source to a fermentation system such that one or more micro-organisms convert a substrate comprising CO to butanol. In one aspect the invention uses a sulfur additive comprising inorganic sulfur compounds having a +2 to a +4 sulfur oxidation state that produces sulfur oxoanions and hydrosulfur oxoanions in an aqueous fermentation medium.

Abstract translation: 本发明涉及通过微生物发酵生产丁醇和丁酸酯的方法的改进，特别是通过微生物发酵包含CO和添加无机硫添加剂的基质来生产醇。 更特别地涉及向发酵系统提供无机有机硫源，使得一种或多种微生物将包含CO的底物转化为丁醇。 在一个方面，本发明使用包含在含水发酵培养基中产生硫氧代阴离子和硫代氧代阴离子的具有+2至+4硫氧化态的无机硫化合物的硫添加剂。

公开(公告)号：US09034617B2

公开(公告)日：2015-05-19

申请号：US13828542

申请日：2013-03-14

Applicant: COSKATA, INC.

Inventor： Robert Hickey ,  Jianxin Du ,  Andrew Reeves ,  Richard E. Tobey

IPC: C12P7/16 ,  C12P7/06 ,  C12P7/04

CPC classification number: C12P7/16 ,  C12N1/20 ,  C12N1/38 ,  C12P7/04 ,  C12P7/06 ,  Y02E50/10 ,  Y02E50/17

Abstract: Processes are disclosed for the anaerobic bioconversion of syngas to oxygenated organic compound that use an in situ method for protecting the microorganisms from hydrogen cyanide contained in the syngas that passes to the fermentation broth. The fermentation broth is maintained at a pH of between about 4 and 6, and dissolved metal cation of one or more of iron, cobalt, nickel and zinc is provided to the fermentation broth in an amount sufficient to form, under the conditions of the fermentation broth, a substantially insoluble metal complex with the metal cation and cyanide anion. The rate of formation of the insoluble complex is sufficiently high that that the amount of cyanide that is taken up by microorganisms does not result in an undue adverse effect on the population of microorganisms.

Abstract translation: 公开了将合成气厌氧生物转化为含氧有机化合物的方法，其使用原位方法保护微生物免受通过发酵液的合成气中所含的氰化氢。 发酵液的pH值保持在4〜6左右之间，并在发酵液中提供一种或多种铁，钴，镍，锌溶解的金属阳离子，其量足以在发酵条件下形成 肉汤，与金属阳离子和氰化物阴离子基本不溶的金属络合物。 不溶性络合物的形成速率足够高，使得微生物吸收的氰化物的量不会对微生物群体产生不适当的不利影响。