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公开(公告)号：US20230138356A1
公开(公告)日：2023-05-04
申请号：US18147546
申请日：2022-12-28
Applicant: Cytiva Sweden AB
Inventor： Key Hyckenberg , Kjell Karlsson , Stefan Willehadson , Orjan Bo Grelsson
IPC: G16H40/67 , G06F16/955 , G06F3/0483 , G06F3/04842 , H04L67/025 , H04L67/125
Abstract: A method, system, gateway and computer program for remote controlling and monitoring of at least one instrument, for example a bioprocessing instrument. The system can comprise: at least one instrument to be controlled and/or monitored; at least one instrument server connected to the at least one instrument, said instrument server comprising an instrument control software; at least one gateway connected to the at least one instrument server; a transferring means provided in the at least one instrument server, said transferring means being arranged to receive information from the at least one connected instrument and forward said information to the at least one gateway.
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公开(公告)号：US20210201032A1
公开(公告)日：2021-07-01
申请号：US17056484
申请日：2019-05-21
Applicant: Cytiva Sweden AB
Inventor： Petra Bangtsson , Johan Arthursson , Key Hyckenberg , Lotta Hedkvist
Abstract: The present invention relates to a method of automated configuration in a bioprocess system (10) and to verify a process defined by a flow path representation. The method comprises the steps of: capturing one image of the bioprocess system (10) comprising tubing (50) for the fluid communication between units of the bioprocess system (10); analyzing the captured image to identify the tubing (50) connecting units of the bioprocess system (10); producing a processed representation from the captured image wherein at least a part of the tubing (50) is identified; and comparing the processed representation with the flow path representation to verify their functional concordance.
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公开(公告)号：US12019058B2
公开(公告)日：2024-06-25
申请号：US17938618
申请日：2022-10-06
Applicant: Cytiva Sweden AB
Inventor： Jens Widehammar , Key Hyckenberg , Orjan Grelsson , Lars Mattsson , Kjell Karlsson
CPC classification number: G01N30/8658 , G01N2030/027
Abstract: The present invention relates to a liquid chromatography system configured to operate with at least one column and configured for purification of a sample comprising a target product using a predefined process. The liquid chromatography system comprises a controller configured to: control the operation of the chromatography system to run the predefined process; retrieve column data accessible from a data storage, the column data being specific to each column; and adapt at least one process parameter of the predefined process for each column based on column data. Whereby the predefined process is adapted to each column to obtain the target product and maintain the performance of the liquid chromatography system.
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公开(公告)号：US11862335B2
公开(公告)日：2024-01-02
申请号：US18147546
申请日：2022-12-28
Applicant: Cytiva Sweden AB
Inventor： Key Hyckenberg , Kjell Karlsson , Stefan Willehadson , Orjan Bo Grelsson
IPC: G08B21/18 , G06K19/077 , G06F9/445 , G06F9/455 , G16H40/67 , G06F16/955 , G06F3/0483 , G06F3/04842 , H04L67/025 , H04L67/125
CPC classification number: G16H40/67 , G06F3/0483 , G06F3/04842 , G06F16/9558 , H04L67/025 , H04L67/125
Abstract: A method, system, gateway and computer program for remote controlling and monitoring of at least one instrument, for example a bioproces sing instrument. The system can comprise: at least one instrument to be controlled and/or monitored; at least one instrument server connected to the at least one instrument, said instrument server comprising an instrument control software; at least one gateway connected to the at least one instrument server; a transferring means provided in the at least one instrument server, said transferring means being arranged to receive information from the at least one connected instrument and forward said information to the at least one gateway.
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公开(公告)号：US20210239662A1
公开(公告)日：2021-08-05
申请号：US16975324
申请日：2019-02-20
Applicant: Cytiva Sweden AB
Inventor： Jens Widehammar , Key Hyckenberg , Orjan Grelsson , Lars Mattsson , Kjell Karlsson
IPC: G01N30/86
Abstract: The present invention relates to a liquid chromatography system (90) configured to operate with at least one column and configured for purification of a sample comprising a target product using a predefined process. The liquid chromatography system comprises a controller (91) configured to: control the operation of the chromatography system to run the predefined process; retrieve column data accessible from a data storage, the column data being specific to each column; and adapt at least one process parameter of the predefined process for each column based on column data. Whereby the predefined process is adapted to each column to obtain the target product and maintain the performance of the liquid chromatography system.
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Patent Agency Ranking
公开(公告)号：US12223716B2
公开(公告)日：2025-02-11
申请号：US18525144
申请日：2023-11-30
Applicant: Cytiva Sweden AB
Inventor： Petra Bangtsson , Johan Arthursson , Key Hyckenberg , Lotta Hedkvist
Abstract: A method of automated configuration in a bioprocess system and to verify a process defined by a flow path representation. The method comprises the steps of: capturing one image of the bioprocess system comprising tubing for the fluid communication between units of the bioprocess system; analyzing the captured image to identify the tubing connecting units of the bioprocess system; producing a processed representation from the captured image wherein at least a part of the tubing is identified; and comparing the processed representation with the flow path representation to verify their functional concordance.
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公开(公告)号：US11493489B2
公开(公告)日：2022-11-08
申请号：US16975324
申请日：2019-02-20
Applicant: Cytiva Sweden AB
Inventor： Jens Widehammar , Key Hyckenberg , Orjan Grelsson , Lars Mattsson , Kjell Karlsson
Abstract: The present invention relates to a liquid chromatography system (90) configured to operate with at least one column and configured for purification of a sample comprising a target product using a predefined process. The liquid chromatography system comprises a controller (91) configured to: control the operation of the chromatography system to run the predefined process; retrieve column data accessible from a data storage, the column data being specific to each column; and adapt at least one process parameter of the predefined process for each column based on column data. Whereby the predefined process is adapted to each column to obtain the target product and maintain the performance of the liquid chromatography system.
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公开(公告)号：US20220163955A1
公开(公告)日：2022-05-26
申请号：US17437085
申请日：2020-03-18
Applicant: Cytiva Sweden AB
Inventor： Key Hyckenberg , Magnus Karlsson , Christoffer Hultqvist , Henrik Lundkvist
IPC: G05B23/02 , G05B19/418
Abstract: The present disclosure relates to a method and system for monitoring a bio-pharmaceutical process, said bio-pharmaceutical process being controlled based on as set of instructions for controlling said biopharmaceutical process. The method comprises the following steps performed by a bio-pharmaceutical process monitoring element: obtaining (S11) said set of instructions for controlling the biopharmaceutical process, and while the instructions of the set of instructions for controlling the bio-pharmaceutical process are executed, for each executed instruction receiving (S13) an execution status update indicating which instruction is presently executed or has just been finished, and forming (S14) an execution status indication relating the instruction presently executed or just finished to its position in the set of instructions based on the received execution status update.
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公开(公告)号：US11321065B2
公开(公告)日：2022-05-03
申请号：US16486546
申请日：2018-02-22
Applicant: Cytiva Sweden AB
Inventor： Key Hyckenberg , Kjell Karlsson , Par Haggblad , Niklas Engblom
Abstract: Disclosed is a method for automatic installation and setting up of an instrument (1), comprising the steps of: connecting (S1) the instrument (1) to a service software system (15) in a network (19) via a first communication interface (6); sending (S3) identification information (5) of the instrument (1) from the instrument to the service software system (15) via the first communication interface (6); recognizing (S5) in the service software system (15) at least one characteristic of the instrument (1) by analyzing the identification information (5); based on said at least one characteristic or identification information, creating (S7) by the service software system (15) dedicated high level control software (25) comprising parts of the control software needed for the instrument; based on said at least one characteristic or identification information, sending (S9) to the instrument (1) from the service software system (15) software to enable a second communication interface (16), and low level control software components needed for local control of the instrument, installing (S11) and configuring in the instrument the low level control software components received from the service software system; starting (S13) a built-in control software (9) in the instrument; using the (S15) the built-in control software in the instrument to access the high level control software dedicated for the instrument via the first, or a second communication interface (16), said built-in control software using the low level control software to monitor and control the instrument.
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公开(公告)号：US12188911B2
公开(公告)日：2025-01-07
申请号：US17602701
申请日：2020-04-16
Applicant: CYTIVA SWEDEN AB
Inventor： Jens Widehammar , Key Hyckenberg , Örjan Grelsson , Lars Mattsson , Kjell Karlsson
Abstract: A chromatography system arranged to perform automated chromatography column efficiency testing for a specific column to determine efficiency parameters and to further provide guidance to the user. The system has a controller arranged to automatically access data to enable the calculation of a column compression plate height, said data being derived from at least stored parameters of the specific column and the resin to be used in the column, to calculate the efficiency of the column.
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