Apparatus, method, and computer program product for adapting a predefined liquid chromatography process

    公开(公告)号:US11493489B2

    公开(公告)日:2022-11-08

    申请号:US16975324

    申请日:2019-02-20

    Abstract: The present invention relates to a liquid chromatography system (90) configured to operate with at least one column and configured for purification of a sample comprising a target product using a predefined process. The liquid chromatography system comprises a controller (91) configured to: control the operation of the chromatography system to run the predefined process; retrieve column data accessible from a data storage, the column data being specific to each column; and adapt at least one process parameter of the predefined process for each column based on column data. Whereby the predefined process is adapted to each column to obtain the target product and maintain the performance of the liquid chromatography system.

    Method and a system for installation of an instrument

    公开(公告)号:US11321065B2

    公开(公告)日:2022-05-03

    申请号:US16486546

    申请日:2018-02-22

    Abstract: Disclosed is a method for automatic installation and setting up of an instrument (1), comprising the steps of: connecting (S1) the instrument (1) to a service software system (15) in a network (19) via a first communication interface (6); sending (S3) identification information (5) of the instrument (1) from the instrument to the service software system (15) via the first communication interface (6); recognizing (S5) in the service software system (15) at least one characteristic of the instrument (1) by analyzing the identification information (5); based on said at least one characteristic or identification information, creating (S7) by the service software system (15) dedicated high level control software (25) comprising parts of the control software needed for the instrument; based on said at least one characteristic or identification information, sending (S9) to the instrument (1) from the service software system (15) software to enable a second communication interface (16), and low level control software components needed for local control of the instrument, installing (S11) and configuring in the instrument the low level control software components received from the service software system; starting (S13) a built-in control software (9) in the instrument; using the (S15) the built-in control software in the instrument to access the high level control software dedicated for the instrument via the first, or a second communication interface (16), said built-in control software using the low level control software to monitor and control the instrument.

    Apparatus, Method, and Computer Program Product for Adapting a Predefined Liquid Chromatography Process

    公开(公告)号:US20230028051A1

    公开(公告)日:2023-01-26

    申请号:US17938618

    申请日:2022-10-06

    Abstract: The present invention relates to a liquid chromatography system configured to operate with at least one column and configured for purification of a sample comprising a target product using a predefined process. The liquid chromatography system comprises a controller configured to: control the operation of the chromatography system to run the predefined process; retrieve column data accessible from a data storage, the column data being specific to each column; and adapt at least one process parameter of the predefined process for each column based on column data. Whereby the predefined process is adapted to each column to obtain the target product and maintain the performance of the liquid chromatography system.

    A CHROMATOGRAPHY SYSTEM
    5.
    发明申请

    公开(公告)号:US20220163493A1

    公开(公告)日:2022-05-26

    申请号:US17602701

    申请日:2020-04-16

    Abstract: Disclosed is a chromatography system arranged to perform automated chromatography column efficiency testing for a specific column to determine efficiency parameters such as h and As and optionally to further provide guidance to the user with respect to column efficiency, the system having a controller arranged to automatically access data to enable the calculation of a column compression plate height, said data being derived from at least stored parameters of the specific column and the resin to be used in that column, thereby to calculate the efficiency of the column.

    Chromatography system
    6.
    发明授权

    公开(公告)号:US12188911B2

    公开(公告)日:2025-01-07

    申请号:US17602701

    申请日:2020-04-16

    Abstract: A chromatography system arranged to perform automated chromatography column efficiency testing for a specific column to determine efficiency parameters and to further provide guidance to the user. The system has a controller arranged to automatically access data to enable the calculation of a column compression plate height, said data being derived from at least stored parameters of the specific column and the resin to be used in the column, to calculate the efficiency of the column.

    Apparatus, Method, and Computer Program Product for Adapting a Predefined Liquid Chromatography Process

    公开(公告)号:US20210239662A1

    公开(公告)日:2021-08-05

    申请号:US16975324

    申请日:2019-02-20

    Abstract: The present invention relates to a liquid chromatography system (90) configured to operate with at least one column and configured for purification of a sample comprising a target product using a predefined process. The liquid chromatography system comprises a controller (91) configured to: control the operation of the chromatography system to run the predefined process; retrieve column data accessible from a data storage, the column data being specific to each column; and adapt at least one process parameter of the predefined process for each column based on column data. Whereby the predefined process is adapted to each column to obtain the target product and maintain the performance of the liquid chromatography system.

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