Process for preparing 3-(1H-tetrazol-5-yl)-4(3H)-quinazolinone
    3.
    发明授权
    Process for preparing 3-(1H-tetrazol-5-yl)-4(3H)-quinazolinone 失效
    制备3-(1H-四唑-5-基)-4(3H) - 喹唑啉酮的方法

    公开(公告)号:US4929728A

    公开(公告)日:1990-05-29

    申请号:US430285

    申请日:1989-11-02

    IPC分类号: C07D403/04

    CPC分类号: C07D403/04

    摘要: A process for preparing 3-(1H-tetrazol-5-yl)-4(3H)-quinazolinone ammonium salts of the formula I: ##STR1## wherein: R is hydrogen, halogen, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 alkoxy,which process comprises:reacting ethyl N-(1H-tetrazol-5-yl) formimidate in an inert solvent with substituted anthranilamide of the formula IV ##STR2## wherein R is as defined above. The process is simpler than prior processes for preparing the same compounds and thus is economically valuable.

    摘要翻译: 制备式I的3-(1H-四唑-5-基)-4(3H) - 喹唑啉酮铵盐的方法:其中:R是氢,卤素,C 1 -C 3烷基或C 1 -C 3烷基, C3烷氧基,该方法包括:使N-(1H-四唑-5-基)甲亚胺酸乙酯在惰性溶剂中与取代的式IV化合物(IV)反应,其中R如上定义。 该方法比用于制备相同化合物的先前方法简单,因此在经济上是有价值的。