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公开(公告)号：US20090209647A1
公开(公告)日：2009-08-20
申请号：US11994617
申请日：2006-06-14
IPC分类号： A61K31/198 , A23L1/305
CPC分类号： A61K31/198 , A23L33/175 , A23L33/30
摘要： A method of improving nutrition and/or treating low grade inflammation in an elderly human subject comprises administering to said subject a cysteine source so as to provide metabolically available cysteine in the diet of said subject in a proportion relative to all available amino acids which is greater that the proportion of cysteine relative to all amino acids which corresponds to the requirements of a healthy young human subject.
摘要翻译： 在老年人受试者中改善营养和/或治疗低度炎症的方法包括向所述受试者施用半胱氨酸源，以便在所述受试者的饮食中以相对于所有受试者的所有可用氨基酸的比例提供代谢可用的半胱氨酸 半胱氨酸相对于所有氨基酸的比例对应于健康年轻人受试者的要求。
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公开(公告)号：US20110269678A1
公开(公告)日：2011-11-03
申请号：US13181213
申请日：2011-07-12
IPC分类号： A61K38/00 , A61K31/405 , A61P3/02 , A23L1/305 , A61K31/197
CPC分类号： A61K31/198 , A23L33/175 , A23L33/30
摘要： A method of improving nutrition and/or treating low grade inflammation in an elderly human subject comprises administering to said subject a cysteine source so as to provide metabolically available cysteine in the diet of said subject in a proportion relative to all available amino acids which is greater that the proportion of cysteine relative to all amino acids which corresponds to the requirements of a healthy young human subject.
摘要翻译： 在老年人受试者中改善营养和/或治疗低度炎症的方法包括向所述受试者施用半胱氨酸源，以便在所述受试者的饮食中以相对于所有受试者的所有可用氨基酸的比例提供代谢可用的半胱氨酸 半胱氨酸相对于所有氨基酸的比例对应于健康年轻人受试者的要求。
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3.发明授权Composition based on amino acids intended for the treatment of sepsis or of an attack bringing about an inflammatory reaction in animals and man 失效基于用于治疗败血症的氨基酸或在动物和人中引起炎症反应的攻击的组合物
公开(公告)号：US5756481A
公开(公告)日：1998-05-26
申请号：US647124
申请日：1996-05-09
申请人： Maurice Arnal , Francis Rose , Denis Breuille , Christiane Obled
发明人： Maurice Arnal , Francis Rose , Denis Breuille , Christiane Obled
IPC分类号： A61K9/08 , A01N43/04 , A23L1/305 , A61K9/14 , A61K31/195 , A61K31/198 , A61K31/425 , A61K31/70 , A61K38/00 , A61P31/04
CPC分类号： A61K31/198 , A23L33/175 , A23L33/40 , A23V2002/00
摘要： Compositions and methods intended to be administered enterally or parenterally for treating sepsis. The composition containing, in a biologically and nutritionally acceptable medium, at least free cysteine or cysteine in the form of a precursor, prodrug, protein or peptide hydrolysate, in a proportion of pharmacologically active cysteine greater than the proportion of cysteine present in a nutritional composition corresponding to the requirements of a healthy man, the proportion of cysteine being determined with respect to all the amino acids present in the composition.
摘要翻译： 用于肠道或胃肠外用于治疗败血症的组合物和方法。 所述组合物在生物和营养上可接受的培养基中至少含有前体，前药，蛋白质或肽水解产物形式的游离半胱氨酸或半胱氨酸，其比例大于存在于营养组合物中的半胱氨酸的比例的药理活性半胱氨酸 对应于健康人的要求，相对于组合物中存在的所有氨基酸确定半胱氨酸的比例。
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公开(公告)号：US07691906B2
公开(公告)日：2010-04-06
申请号：US11204885
申请日：2005-08-16
申请人： Marco Turini , Claudia Roessle , Denis Breuille , Gayle Crozier-Willi , Paul André Finot , Myriam Richelle , Guy Dutot , Christiane Obled
发明人： Marco Turini , Claudia Roessle , Denis Breuille , Gayle Crozier-Willi , Paul André Finot , Myriam Richelle , Guy Dutot , Christiane Obled
IPC分类号： A61K31/00 , A61K31/20 , A61K31/201 , A61K31/202 , A61K31/225 , A61K31/70 , A61K38/00 , A61P3/00
摘要： A composition for use as a medicament, functional food or nutritional product is described which comprises at least one lipid wherein the lipid provides greater than 35% total energy of the composition. A preferred embodiment comprises a n-6/n-3 fatty acid ratio of about 2/1 to 7/1. In addition, a method of preparing the composition; use of the composition in the manufacture of a medicament, functional food or nutritional product; and a method of treatment or treatment or prevention of sepsis or inflammatory shock which comprises administering an effective amount of the composition are described.
摘要翻译： 描述了用作药物，功能性食品或营养产品的组合物，其包含至少一种脂质，其中所述脂质提供组合物的总能量的35％以上。 优选的实施方案包括约2/1至7/1的n-6 / n-3脂肪酸比。 另外，制备组合物的方法; 在制备药物，功能性食品或营养产品中使用该组合物; 以及治疗或治疗或预防败血症或炎性休克的方法，其包括施用有效量的组合物。
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5.发明授权Composition based on amino acids intended for the treatment of sepsis or of an attack bringing about an inflammatory reaction, in animals and man 失效基于用于治疗败血症或引起炎症反应的攻击的氨基酸的组合物，在动物和人中
公开(公告)号：US5863906A
公开(公告)日：1999-01-26
申请号：US896611
申请日：1997-07-18
申请人： Maurice Arnal , Francis Rose , Denis Breuille , Christiane Obled
发明人： Maurice Arnal , Francis Rose , Denis Breuille , Christiane Obled
IPC分类号： A61K9/08 , A01N43/04 , A23L1/305 , A61K9/14 , A61K31/195 , A61K31/198 , A61K31/425 , A61K31/70 , A61K38/00 , A61P31/04
CPC分类号： A61K31/198 , A23L33/175 , A23L33/40 , A23V2002/00
摘要： Compositions and methods intended to be administered enterally or parenterally for treating sepsis. The composition containing, in a biologically and nutritionally acceptable medium, at least free cysteine or cysteine in the form of a precursor, prodrug, protein or peptide hydrolysate, in a proportion of pharmacologically active cysteine greater than the proportion of cysteine present in a nutritional composition corresponding to the requirements of a healthy man, the proportion of cysteine being determined with respect to all the amino acids present in the composition.
摘要翻译： 用于肠道或胃肠外用于治疗败血症的组合物和方法。 所述组合物在生物和营养上可接受的培养基中至少含有前体，前药，蛋白质或肽水解产物形式的游离半胱氨酸或半胱氨酸，其比例大于存在于营养组合物中的半胱氨酸的比例的药理活性半胱氨酸 对应于健康人的要求，相对于组合物中存在的所有氨基酸确定半胱氨酸的比例。
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公开(公告)号：US09233090B2
公开(公告)日：2016-01-12
申请号：US13880923
申请日：2011-10-19
申请人： Denis Breuille , Isabelle Papet , Karine Vidal
发明人： Denis Breuille , Isabelle Papet , Karine Vidal
IPC分类号： A61K31/198 , A23L1/305
CPC分类号： A61K31/198 , A23L33/175
摘要： The present invention relates to the field of nutrition; in particular to the prevention and/or treatment of malnutrition. One embodiment of the present invention relates to a nutritional composition enriched in cysteine for use in the treatment and/or prevention of malnutrition and disorders related thereto. Such a composition may in particular, but not exclusively, be useful for the elderly population.
摘要翻译： 本发明涉及营养领域; 特别是预防和/或治疗营养不良。 本发明的一个实施方案涉及富含半胱氨酸的营养组合物，用于治疗和/或预防与其相关的营养不良和紊乱。 这样的组合物可能特别但不排他地对老年人有用。
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公开(公告)号：US20130225486A1
公开(公告)日：2013-08-29
申请号：US13880923
申请日：2011-10-19
申请人： Denis Breuille , Isabelle Papet , Karine Vidal
发明人： Denis Breuille , Isabelle Papet , Karine Vidal
IPC分类号： A61K31/198 , A23L1/305
CPC分类号： A61K31/198 , A23L33/175
摘要： The present invention relates to the field of nutrition; in particular to the prevention and/or treatment of malnutrition. One embodiment of the present invention relates to a nutritional composition enriched in cysteine for use in the treatment and/or prevention of malnutrition and disorders related thereto. Such a composition may in particular, but not exclusively, be useful for the elderly population.
摘要翻译： 本发明涉及营养领域; 特别是预防和/或治疗营养不良。 本发明的一个实施方案涉及富含半胱氨酸的营养组合物，用于治疗和/或预防与其相关的营养不良和紊乱。 这样的组合物可能特别但不排他地对老年人有用。
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公开(公告)号：US08409592B2
公开(公告)日：2013-04-02
申请号：US13120118
申请日：2009-09-14
申请人： Karine Vidal , Eric Delpierre , Cecile Loi , Christophe Moinard , Christine Charrueau , Denis Breuille , Luc Cynober
发明人： Karine Vidal , Eric Delpierre , Cecile Loi , Christophe Moinard , Christine Charrueau , Denis Breuille , Luc Cynober
IPC分类号： A61K39/00
CPC分类号： A61K35/20 , A61K35/745 , A61K35/747 , A61K36/064 , A61K38/018 , A61K2300/00
摘要： The present invention generally relates to the field of nutrition and health. In particular, the present invention provides a composition that can be used to maintain or improve thymus health. One embodiment of the present invention is the use of whey or at least one protein fraction thereof for the preparation of a composition to maintain or improve thymus function.
摘要翻译： 本发明一般涉及营养与健康领域。 特别地，本发明提供可用于维持或改善胸腺健康的组合物。 本发明的一个实施方案是使用乳清或其至少一种蛋白质级分来制备组合物以维持或改善胸腺功能。
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公开(公告)号：US07794744B2
公开(公告)日：2010-09-14
申请号：US10257208
申请日：2001-04-03
申请人： Olivier Ballevre , Julio Boza , Denis Breuille , Paul-André Finot , Véronique Jaussan , Claudia Roessle , Thomas Schweizer
发明人： Olivier Ballevre , Julio Boza , Denis Breuille , Paul-André Finot , Véronique Jaussan , Claudia Roessle , Thomas Schweizer
IPC分类号： A61K47/00
CPC分类号： A61K45/06 , A23L33/135 , A23L33/15 , A23L33/16 , A23L33/175 , A23L33/30 , A23L33/40 , A23V2002/00 , A23Y2220/63 , A23Y2300/00 , A23V2250/062 , A23V2250/0616 , A23V2250/0648 , A23V2250/061 , A23V2250/0642 , A23V2250/708 , A23V2250/1642 , A23V2250/1626 , A23V2250/206 , A23V2250/712 , A23V2250/211
摘要： The present invention relates to a method for preparing an enteral nutrition at the bed of a patient, which involves the use of a standard enteral solution to which is added, via a closed system, one or more compositions in module form, containing selected nutrients, adapted for a specific clinical condition. The present invention also pertains to the different modules, that are preferably in dry form and to the use thereof in the treatment and/or nourishment of a critically ill person.
摘要翻译： 本发明涉及一种在患者床上制备肠内营养的方法，其涉及使用通过封闭系统加入一种或多种包含所选营养物的模块形式的组合物的标准肠内溶液， 适应特定的临床状况。 本发明还涉及不同的模块，其优选为干燥形式，并且涉及在危重患者的治疗和/或营养中的应用。
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公开(公告)号：US06995189B1
公开(公告)日：2006-02-07
申请号：US10070486
申请日：2000-09-07
申请人： Marco Turini , Claudia Roessle , Denis Breuille , Gayle Crozier-Willi , Paul André Finot , Myriam Richelle , Guy Dutot
发明人： Marco Turini , Claudia Roessle , Denis Breuille , Gayle Crozier-Willi , Paul André Finot , Myriam Richelle , Guy Dutot
IPC分类号： A61K31/00 , A61K31/20 , A61K31/201 , A61K31/202 , A61K31/225
摘要： A composition for use as a medicament or nutritional product is described which comprises at least one lipid wherein the lipid provides greater tan 35% total energy of the composition. A prefered embodiment comprises a n-6/n-3 fatty acid ratio of about 2/1 to 7/1. In addition, a method of preparing the composition; use of the composition in the manufacture of a medicament or nutritional product; and a method of treatment or prevention of sepsis or inflammatory shock which comprises administering an effective amount of the composition are described.
摘要翻译： 描述了用作药物或营养产品的组合物，其包含至少一种脂质，其中所述脂质提供组合物的更大的35％总能量。 优选的实施方案包括约2/1至7/1的n-6 / n-3脂肪酸比。 另外，制备组合物的方法; 在制备药物或营养产品中使用该组合物; 以及治疗或预防败血症或炎性休克的方法，其包括施用有效量的组合物。
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