公开(公告)号：US20240074682A1

公开(公告)日：2024-03-07

申请号：US18241658

申请日：2023-09-01

Applicant: DexCom, Inc.

Inventor： Berta Esteban Fernandez de Avila ,  Devon M. Headen ,  Stacy Hunt DuVall ,  Jiong Zou ,  Shane Richard Parnell ,  Nicholas Vincent Apollo ,  Joshua Ray Windmiller

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/318

CPC classification number: A61B5/14546 ,  A61B5/14865 ,  A61B5/318 ,  A61B5/6847

Abstract: Devices and methods for measuring a concentration of a target analyte in a biological fluid in vivo are provided herein. In some examples, a device includes an indwelling sensor and sensor electronics. The sensor may include a substrate; a first electrode disposed on the substrate; an ionophore disposed on the substrate to selectively transport the target ion to or within the first electrode; and a second electrode disposed on the substrate. The sensor electronics is configured to generate a signal corresponding to an electromotive force which is at least partially based on a potential difference that is generated between the first electrode and the second electrode responsive to the ionophore transporting the target ion to the first electrode.

公开(公告)号：US20230064744A1

公开(公告)日：2023-03-02

申请号：US17899135

申请日：2022-08-30

Applicant: Dexcom, Inc.

Inventor： Samuel Isaac Epstein ,  Devon Headen ,  Avid Najdahmadi ,  Joseph J Baker ,  Kevin Cheng ,  Nicholas Vincent Apollo ,  Berta Esteban Fernandez de Avila ,  Daud Abd al-Malik Zoss ,  Wenjie Lan

IPC: A61B5/00 ,  A61B5/369

Abstract: An augmented analyte monitoring system is described. The augmented analyte monitoring system includes a wearable analyte monitoring device that includes a transmitter and an analyte sensor to obtain analyte data of a user, and an analyte augmentation wearable that includes one or more sensors (e.g., physical and/or biochemical sensors) to obtain additional physiological data for augmenting the analyte data of the user. The analyte augmentation wearable is communicably coupled to the wearable analyte monitoring device. The augmented analyte monitoring system further includes a sensor hub implemented at a computing device to obtain a data packet containing both the analyte data and the additional physiological data from at least one of the wearable analyte monitoring device or the analyte augmentation wearable, and augment the analyte data by storing the analyte data in association with the additional physiological data.

公开(公告)号：US20250025076A1

公开(公告)日：2025-01-23

申请号：US18399162

申请日：2023-12-28

Applicant: DexCom, Inc.

Inventor： Shuyu Lin ,  Daiting Rong ,  Stacy Hunt DuVall ,  Wenjie Lan ,  Jason M. Halac ,  Jiong Zou ,  Devon M. Headen ,  Shanger Wang ,  Shane Richard Parnell ,  Berta Esteban Fernandez de Avila ,  Shannon Reuben Woodruff

IPC: A61B5/1473

Abstract: An analyte monitoring sensor configured for in vivo measurement of at least one analyte is provided, the sensor comprising a substrate having a substrate surface, an aptamer protective layer encapsulating at least a portion of the substrate surface, the aptamer protective layer permeable to the at least one analyte, one or more aptamer conjugates associated with at least a portion of the substrate surface and positioned between the aptamer protective layer and the substrate for obtaining measurements related to the at least one analyte in vivo. Methods of extending in vivo performance of the analyte monitoring sensor are also described.