公开(公告)号：US20240074682A1

公开(公告)日：2024-03-07

申请号：US18241658

申请日：2023-09-01

Applicant: DexCom, Inc.

Inventor： Berta Esteban Fernandez de Avila ,  Devon M. Headen ,  Stacy Hunt DuVall ,  Jiong Zou ,  Shane Richard Parnell ,  Nicholas Vincent Apollo ,  Joshua Ray Windmiller

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/318

CPC classification number: A61B5/14546 ,  A61B5/14865 ,  A61B5/318 ,  A61B5/6847

Abstract: Devices and methods for measuring a concentration of a target analyte in a biological fluid in vivo are provided herein. In some examples, a device includes an indwelling sensor and sensor electronics. The sensor may include a substrate; a first electrode disposed on the substrate; an ionophore disposed on the substrate to selectively transport the target ion to or within the first electrode; and a second electrode disposed on the substrate. The sensor electronics is configured to generate a signal corresponding to an electromotive force which is at least partially based on a potential difference that is generated between the first electrode and the second electrode responsive to the ionophore transporting the target ion to the first electrode.

公开(公告)号：US20230064744A1

公开(公告)日：2023-03-02

申请号：US17899135

申请日：2022-08-30

Applicant: Dexcom, Inc.

Inventor： Samuel Isaac Epstein ,  Devon Headen ,  Avid Najdahmadi ,  Joseph J Baker ,  Kevin Cheng ,  Nicholas Vincent Apollo ,  Berta Esteban Fernandez de Avila ,  Daud Abd al-Malik Zoss ,  Wenjie Lan

IPC: A61B5/00 ,  A61B5/369

Abstract: An augmented analyte monitoring system is described. The augmented analyte monitoring system includes a wearable analyte monitoring device that includes a transmitter and an analyte sensor to obtain analyte data of a user, and an analyte augmentation wearable that includes one or more sensors (e.g., physical and/or biochemical sensors) to obtain additional physiological data for augmenting the analyte data of the user. The analyte augmentation wearable is communicably coupled to the wearable analyte monitoring device. The augmented analyte monitoring system further includes a sensor hub implemented at a computing device to obtain a data packet containing both the analyte data and the additional physiological data from at least one of the wearable analyte monitoring device or the analyte augmentation wearable, and augment the analyte data by storing the analyte data in association with the additional physiological data.

公开(公告)号：US20240389908A1

公开(公告)日：2024-11-28

申请号：US18673130

申请日：2024-05-23

Applicant: Dexcom, Inc.

Inventor： Nicholas Vincent Apollo ,  Jonathon Clemens ,  Wenjie Lan ,  Chris Dring

IPC: A61B5/1495 ,  A61B5/145 ,  A61B5/1486

Abstract: Analyte monitoring device calibration is described. A calibration system generates calibration results for multiple analyte monitoring devices during a calibration evaluation process. To do so, the calibration system implements a calibration board that includes a single ground electrode shared by, but not physically connected to, the multiple analyte monitoring devices. An input voltage is applied to an analyte-sensing element of each of the multiple analyte monitoring devices. Analyte-sensing elements and the common ground electrode are placed into/in contact with a reference bath that includes a known concentration of an analyte to be measured. The input voltage causes each analyte-sensing element to generate an electrical current that is indicative of the reference bath analyte concentration. The calibration system includes a current meter that monitors the electrical current generated by each of the multiple analyte monitoring devices, which is interpreted by the calibration system to generate the calibration results.

公开(公告)号：US20230301553A1

公开(公告)日：2023-09-28

申请号：US18185455

申请日：2023-03-17

Applicant: Dexcom, Inc.

Inventor： Daiting Rong ,  Xiong Peng ,  Nicholas Vincent Apollo ,  Jonathan M. Hughes ,  Wenjie Lan ,  Chris W, Dring ,  Shane Richard Parnell ,  Ryan Lee Knoy ,  Peter C. Simpson ,  Joshua Ray Windmiller ,  Nai-Jen Chang ,  Jie Zhu ,  Matthew S. Brown ,  Eric Ruike Zhao

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/256 ,  A61B5/257

CPC classification number: A61B5/1451 ,  A61B5/14865 ,  A61B5/14532 ,  A61B5/256 ,  A61B5/257 ,  A61B5/14546

Abstract: Disclosed herein are systems and methods for a continuous analyte monitoring system for measuring a concentration of a first analyte and concentration of a second analyte in a host. One such system utilizes a working electrode and a reference electrode to measure glucose concentration and oxygen concentration in bodily fluid of a host. The system includes a sensor control circuit that applies a first bias condition to the sensor to measure a first signal generated by the sensor indicative of a concentration of the first analyte. The sensor control circuit also applies a second bias condition to the sensor to measure a second signal generated by the sensor indicative of a concentration of a second analyte at the host.