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公开(公告)号：US12268599B2
公开(公告)日：2025-04-08
申请号：US17341844
申请日：2021-06-08
Applicant: Edwards Lifesciences Corporation
Inventor： Michael C. Murad , Michael R. Bialas
Abstract: A delivery apparatus can include a handle, a first shaft extending from the handle and having a proximal end portion coupled to the handle and a distal end portion and a second shaft extending coaxially over the first shaft and having a proximal end portion coupled to the handle and a distal end portion. The delivery apparatus can further include a shoulder coupled to the distal end portion of the second shaft and having a flared end portion configured to abut a prosthetic valve positioned around the first shaft in a radially compressed state, an extension portion extending from the shoulder, and at least one radiopaque marker disposed on the extension portion at a location within the prosthetic valve when the prosthetic valve is in a radially compressed configuration on the first shaft.
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公开(公告)号：US20240423785A1
公开(公告)日：2024-12-26
申请号：US18824171
申请日：2024-09-04
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Michael C. Murad , Gonzalo German Angelico , Michael R. Bialas
Abstract: Balloon covers for a delivery apparatus for a prosthetic valve are disclosed. As one embodiment, a balloon cover includes first and second shell members that are configured to matingly engage with each other, each of the first and second shell members including a first portion and a second portion, the second portion having a larger width than the first portion. The first portions of the first and second shell members define a first cavity configured to receive a distal end portion of the delivery apparatus and at least a portion of an inflatable balloon mounted on the distal end portion of the delivery apparatus. The second portions of the first and second shell members define a second cavity configured to receive a positioning device mounted on the distal end portion of the delivery apparatus, proximal to a valve mounting portion of the distal end portion of the delivery apparatus.
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公开(公告)号：US20240115381A1
公开(公告)日：2024-04-11
申请号：US17938795
申请日：2022-10-07
Applicant: Edwards Lifesciences Corporation
Inventor： Michael C. Murad
IPC: A61F2/24
CPC classification number: A61F2/2436 , A61F2/9517
Abstract: A steerable delivery apparatus for an implantable medical device comprises a shaft extending distally from the handle, the shaft having a steering-member lumen extending through a length of the shaft, and a steering member extending through the steering-member lumen, the steering member having a proximal end portion and a distal end portion. A pull ring is disposed along a distal end portion of the shaft, the pull ring comprising a proximal segment having a first diameter and a distal segment having a second diameter smaller than the first diameter. The distal end portion of the steering member is fixed to the distal segment of the pull ring, and an adjustment mechanism is further provided in the handle, the mechanism operatively coupled to the proximal end portion of the steering member and configured to adjust tension in the steering member so as to adjust a curvature of the shaft.
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公开(公告)号：US20220008199A1
公开(公告)日：2022-01-13
申请号：US17487232
申请日：2021-09-28
Applicant: Edwards Lifesciences Corporation
Inventor： Derrick Johnson , Michael C. Murad , Steven M. Ford , Rodolfo Rodriguez
IPC: A61F2/24
Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein. A dual-wireform support frame including an upper and a lower wireform permits expansion of the valve by one or two valve sizes, for example, with a 2-mm gap between each valve size. The lower wireform has a relatively shallow undulation so that it may stretch apart by a small amount and then prevent further expansion of the valve.
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公开(公告)号：US20210267758A1
公开(公告)日：2021-09-02
申请号：US17321358
申请日：2021-05-14
Applicant: Edwards Lifesciences Corporation
Inventor： Michael C. Murad , Hilda Z. Fann , Mark Van Nest , John X. Wang , Derrick Johnson
IPC: A61F2/24
Abstract: A valved conduit including a bioprosthetic aortic heart valve connected to a tubular conduit graft forming an ascending aorta. The conduit graft may attach to the heart valve in a manner that facilitates a redo operation in which the valve is replaced with another valve. A sewing ring may be pre-attached to the inflow end of the graft, and then the valve connected to a delivery holder advanced into the graft and secured to the sewing ring. Dry bioprosthetic valves coupled with conduit grafts sealed with a bioresorbable medium can be stored with the delivery holder.
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Patent Agency Ranking
公开(公告)号：US20200146820A1
公开(公告)日：2020-05-14
申请号：US16740789
申请日：2020-01-13
Applicant: Edwards Lifesciences Corporation
Inventor： Ruggero De Paulis , Michael C. Murad
Abstract: A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. A method of securing a composite valved conduit includes introducing to an excised ascending aorta the sizing tool, measuring the aortic annulus with the prosthetic heart valve sizer, and determining whether the coronary arteries have sufficient length or whether an additional tubular coronary extension segment is required to add to one or both of the ends of the coronary arteries by extending the coronary arteries toward the conduit graft replica.
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公开(公告)号：US10314573B2
公开(公告)日：2019-06-11
申请号：US15385203
申请日：2016-12-20
Applicant: Edwards Lifesciences Corporation
Inventor： Travis Zenyo Oba , Michael C. Murad , Manouchehr A. Miraki , Anthony P. Carcia , Fabian Daniel Schroeder , Raffaele Mazzei , Tyler Douglas Smith
Abstract: Suture clip deployment devices for applying suture clips to sutures are described. Some embodiments can include a generally tubular main body and a vacuum port located at the distal end, a hollow inner body longitudinally slidable within the main body and extending from the main body at its distal end, and a suture recess located in the generally tubular main body. At least one suture clip configured to frictionally fit on an outer surface of the inner body is deployed during use. Clip deployment can occur after a vacuum source is applied to the device so as to draw the suture into the device. The suture lines can be retrieved through the suture recess, and the device can be actuated so as to deliver the suture clip off the delivery device and onto the suture, locking the suture in place.
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公开(公告)号：US10058425B2
公开(公告)日：2018-08-28
申请号：US14850829
申请日：2015-09-10
Applicant: Edwards Lifesciences Corporation
Inventor： Michael C. Murad , Hilda Z. Fann , Mark Van Nest , John X. Wang
CPC classification number: A61F2/2445 , A61F2/06 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2230/0076 , A61F2230/0095 , A61F2240/001 , A61F2250/006
Abstract: A valved conduit including a bioprosthetic aortic heart valve connected to a tubular conduit graft forming an ascending aorta. The conduit graft may attach to the heart valve in a manner that facilitates a redo operation in which the valve is replaced with another valve. A sewing ring may be pre-attached to the inflow end of the graft, and then the valve connected to a delivery holder advanced into the graft and secured to the sewing ring. Dry bioprosthetic valves coupled with conduit grafts sealed with a bioresorbable medium can be stored with the delivery holder.
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公开(公告)号：US20180104058A1
公开(公告)日：2018-04-19
申请号：US15844878
申请日：2017-12-18
Applicant: Edwards Lifesciences Corporation
Inventor： Ruggero De Paulis , Michael C. Murad
CPC classification number: A61F2/2427 , A61F2/06 , A61F2/2496
Abstract: A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. A method of securing a composite valved conduit includes introducing to an excised ascending aorta the sizing tool, measuring the aortic annulus with the prosthetic heart valve sizer, and determining whether the coronary arteries have sufficient length or whether an additional tubular coronary extension segment is required to add to one or both of the ends of the coronary arteries by extending the coronary arteries toward the conduit graft replica.
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公开(公告)号：US20170119375A1
公开(公告)日：2017-05-04
申请号：US15385203
申请日：2016-12-20
Applicant: Edwards Lifesciences Corporation
Inventor： Travis Zenyo Oba , Michael C. Murad , Manouchehr A. Miraki , Anthony P. Carcia , Fabian Daniel Schroeder , Raffaele Mazzei , Tyler Douglas Smith
IPC: A61B17/04
CPC classification number: A61B17/0487 , A61B1/04 , A61B17/0467 , A61B17/0469 , A61B17/0482 , A61B90/30 , A61B2017/00526 , A61B2017/00561 , A61B2017/00783 , A61B2017/00867 , A61B2017/0488
Abstract: Suture clip deployment devices for applying suture clips to sutures are described. Some embodiments can include a generally tubular main body and a vacuum port located at the distal end, a hollow inner body longitudinally slidable within the main body and extending from the main body at its distal end, and a suture recess located in the generally tubular main body. At least one suture clip configured to frictionally fit on an outer surface of the inner body is deployed during use. Clip deployment can occur after a vacuum source is applied to the device so as to draw the suture into the device. The suture lines can be retrieved through the suture recess, and the device can be actuated so as to deliver the suture clip off the delivery device and onto the suture, locking the suture in place.
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