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公开(公告)号:US10195550B2
公开(公告)日:2019-02-05
申请号:US14839779
申请日:2015-08-28
Applicant: EMD Millipore Corporation
Inventor: Jonathan Steen , Mikhail Kozlov , Herbert Lutz , Joseph Parrella , Elizabeth M. Goodrich , Bala Raghunath
Abstract: A method of filtering a liquid feed is described, comprising passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers. A method of filtering a liquid feed is also described comprising passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods of the invention can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.
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公开(公告)号:US11278827B2
公开(公告)日:2022-03-22
申请号:US16427942
申请日:2019-05-31
Applicant: EMD Millipore Corporation
Inventor: Jonathan Steen , Mikhail Kozlov , Herbert Lutz , Joseph Parrella , Elizabeth M. Goodrich , Bala Raghunath
Abstract: Methods of filtering a liquid feed are disclosed. In one version, the method comprises passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers without recirculation through the SPTFF system. In another version, the method of filtering a liquid feed, comprises passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.
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公开(公告)号:US11033839B2
公开(公告)日:2021-06-15
申请号:US16208018
申请日:2018-12-03
Applicant: EMD Millipore Corporation
Inventor: Jonathan Steen , Mikhail Kozlov , Herbert Lutz , Joseph Parrella , Elizabeth M. Goodrich , Bala Raghunath
Abstract: A method of filtering a liquid feed is described, comprising passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers. A method of filtering a liquid feed is also described comprising passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods of the invention can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.
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公开(公告)号:US20150375173A1
公开(公告)日:2015-12-31
申请号:US14750838
申请日:2015-06-25
Applicant: EMD Millipore Corporation
Inventor: Jonathan Steen
CPC classification number: B01D63/12 , B01D61/025 , B01D61/145 , B01D61/147 , B01D63/10 , B01D63/103 , B01D67/0086 , B01D71/68 , B01D2313/14 , B01D2313/143 , B01D2313/146 , B01D2313/50 , B01D2315/10 , B01D2315/16 , B01D2317/02 , C02F1/44 , C02F1/441 , C02F1/442 , C02F1/444 , D06C15/02
Abstract: The present invention provides compact spiral-wound filter elements having cassette-like performance. The invention further provides filtration systems (e.g., TFF systems) and processes (e.g., SPTFF processes) employing compact spiral-wound filter elements having cassette-like performance.
Abstract translation: 本发明提供具有盒状性能的紧凑型螺旋缠绕式过滤元件。 本发明进一步提供使用具有盒状性能的紧凑型螺旋缠绕过滤器元件的过滤系统(例如,TFF系统)和工艺(例如SPTFF工艺)。
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公开(公告)号:US12226737B2
公开(公告)日:2025-02-18
申请号:US16096516
申请日:2017-05-26
Applicant: EMD Millipore Corporation
Inventor: Jonathan Steen
Abstract: The present invention provides a filter element (500) having a radial permeate discharge path (550). The filter element generally includes a closed membrane structure (510) wrapped about a core (530) in reciprocating clockwise and counterclockwise directions, forming semicircular folds of membrane about the core. The semicircular folds of membrane have opposingly situated apical ends (560) separated by a gap. The interior of the closed membrane structure (510) defines a feed channel and the exterior of the closed membrane structure defines at least one permeate channel (522). A radial permeate discharge path (550) extends through the gap between the apical ends of the semicircular folds of membrane. Systems containing, and methods of using, filter elements including radial permeate discharge paths are also provided.
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公开(公告)号:US20220212146A1
公开(公告)日:2022-07-07
申请号:US17656285
申请日:2022-03-24
Applicant: EMD Millipore Corporation
Inventor: Jonathan Steen , George A. Gagne
Abstract: The present invention provides compact spiral-wound filter elements having cassette-like performance. The invention further provides filtration systems (e.g., TFF systems) and processes (e.g., SPTFF processes) employing compact spiral-wound filter elements having cassette-like performance.
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公开(公告)号:US11311841B2
公开(公告)日:2022-04-26
申请号:US16428189
申请日:2019-05-31
Applicant: EMD Millipore Corporation
Inventor: Jonathan Steen , George A. Gagne, Jr.
Abstract: The present invention provides compact spiral-wound filter elements having cassette-like performance. The invention further provides filtration systems (e.g., TFF systems) and processes (e.g., SPTFF processes) employing compact spiral-wound filter elements having cassette-like performance.
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公开(公告)号:US20190282963A1
公开(公告)日:2019-09-19
申请号:US16428189
申请日:2019-05-31
Applicant: EMD Millipore Corporation
Inventor: Jonathan Steen
Abstract: The present invention provides compact spiral-wound filter elements having cassette-like performance. The invention further provides filtration systems (e.g., TFF systems) and processes (e.g., SPTFF processes) employing compact spiral-wound filter elements having cassette-like performance.
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公开(公告)号:US11986772B2
公开(公告)日:2024-05-21
申请号:US17656285
申请日:2022-03-24
Applicant: EMD Millipore Corporation
Inventor: Jonathan Steen
IPC: B01D61/02 , B01D61/08 , B01D61/14 , B01D61/18 , B01D63/10 , B01D63/12 , B01D71/68 , C02F1/44 , D06C15/02 , B01D67/00
CPC classification number: B01D63/12 , B01D61/025 , B01D61/145 , B01D63/10 , B01D63/103 , C02F1/44 , C02F1/441 , C02F1/442 , D06C15/02 , B01D61/147 , B01D67/0086 , B01D71/68 , B01D2313/14 , B01D2313/143 , B01D2313/146 , B01D2313/50 , B01D2315/10 , B01D2315/16 , B01D2317/02 , C02F1/444
Abstract: The present invention provides compact spiral-wound filter elements having cassette-like performance. The invention further provides filtration systems (e.g., TFF systems) and processes (e.g., SPTFF processes) employing compact spiral-wound filter elements having cassette-like performance.
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公开(公告)号:US20220176278A1
公开(公告)日:2022-06-09
申请号:US17682221
申请日:2022-02-28
Applicant: EMD Millipore Corporation
Inventor: Jonathan Steen , Mikhail Kozlov , Herbert Lutz , Joseph Parrella , Elizabeth M. Goodrich , Bala Raghunath
Abstract: Methods of filtering a liquid feed are disclosed. In one version, the method comprises passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers without recirculation through the SPTFF system. In another version, the method of filtering a liquid feed, comprises passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.
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