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1.发明授权Capsule for use in brachytherapy and a combination of a capsule for brachytherapy and a guidewire 有权用于近距离放射治疗的胶囊和用于近距离放射治疗的胶囊和导丝的组合公开(公告)号：US06179768B2
公开(公告)日：2001-01-30
申请号：US09214428
申请日：1999-03-03
IPC分类号： A61M3600
CPC分类号： A61N5/1002 , A61N2005/1025
摘要： A capsule for taking up at least one radioactive source for application in brachytherapy and to be connected to a guidewire, the capsule having a cylindrical mantle that can be closed on the proximal end by a coupling element, and the capsule having a rounded top section at its distal end, the mantle and the inner surface of the top section defining a substantially straight circular-cylindrical cavity, in which the operation at least one radioactive source is placed, the inner surface of the top section, at least in a peripheral area thereof, being curved in distal direction and the cavity continuing somewhat in the top section, and the end of that least one radioactive source, which is located near the inner surface of the top section, is finished in a complementary curved fashion.
摘要翻译： 一种用于吸收至少一个放射源以用于近距离放射治疗并且连接到导丝的胶囊，所述胶囊具有可通过联接元件在近端封闭的圆柱形罩，并且所述胶囊具有圆形顶部， 其顶端，地幔和顶部的内表面限定基本上直的圆柱形空腔，其中放置至少一个放射源的操作，顶部的内表面至少在其周边区域中 ，在远端方向上弯曲并且空腔在顶部部分中稍微延伸，并且位于顶部部分的内表面附近的至少一个放射源的端部以互补的弯曲方式完成。
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公开(公告)号：US06641519B1
公开(公告)日：2003-11-04
申请号：US09788265
申请日：2001-02-16
IPC分类号： A61M3600
CPC分类号： A61N5/1007 , A61N2005/1008
摘要： A drive device in a medical device for driving a wire through a guide tube from a first position with an end of the wire outside an animal body to a second position in which the end is inside the animal body. The drive device comprises first and second elements rotatable relative to each other. The first and second elements each have contact surfaces, that in each rotational position of the first and second elements relative to each other are in contact with each other in a contact area along a common contact plane. A storage space going about the axis is provided for the wire in the first element. The storage space is open along a length of it to the contact surface of the first element. The second element comprises a channel for the wire and is open to the contact plane.
摘要翻译： 一种医疗装置中的驱动装置，用于通过引导管从第一位置驱动电线，其中电线的端部在动物体外部延伸到第二位置，其中端部在动物体内。 驱动装置包括可相对于彼此旋转的第一和第二元件。 第一和第二元件各自具有接触表面，在第一和第二元件的相对于彼此的每个旋转位置中，沿着公共接触平面的接触区域中彼此接触。 为第一个元件中的导线提供围绕轴线的存储空间。 存储空间沿其长度打开到第一元件的接触表面。 第二元件包括用于导线的通道并且对接触平面开放。
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公开(公告)号：US06595908B2
公开(公告)日：2003-07-22
申请号：US09788226
申请日：2001-02-16
IPC分类号： A61M3600
CPC分类号： A61N5/1007 , A61N5/1027 , A61N2005/1008 , A61N2005/1009 , A61N2005/1011
摘要： A modular device for implanting radioactive seeds in an animal body through needles implanted in the body. Trains of radioactive seeds and non-radioactive spacers are assembled in an assembly unit. The assembly unit comprises a device for determining activity of the seeds with an accuracy that allows distinguishing between different activities within tolerance ranges of specified nominal activities for the seeds. After implantation of the seeds in the body a pre-plan may be recalculated taking into consideration actual activities of seeds implanted. Not correctly composed trains may be disposed of. A post-plan may be determined based upon actually measured activities of implanted seeds.
摘要翻译： 用于通过植入体内的针将放射性种子植入动物体内的模块化装置。 放射性种子和非放射性隔离物的火车组装在组装单元中。 组装单元包括用于以准确度确定种子的活动的装置，其允许区分种子指定的标称活动的容许范围内的不同活动。 将种子植入体内后，可以考虑植入种子的实际活动来重新计算预先计划。 不正确组合的火车可能会被处置。 可以基于实际测量的植入种子的活动来确定后期计划。
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4.发明授权Row of radioactive seeds and non-radioactive spacers and connector therefore 失效因此放射性种子行和非放射性隔离物和连接器公开(公告)号：US07008367B2
公开(公告)日：2006-03-07
申请号：US10363551
申请日：2001-09-03
IPC分类号： A61N5/00
CPC分类号： A61N5/1027 , A61N2005/1023
摘要： An arranged row of radioactive seeds and non-radioactive spacers with a predetermined pitch can be provided with physical coherence by applying connectors between the separate seeds and spacers. In a first embodiment the connectors are elongated with introversions at both ends, in a second embodiment a connector also forms a spacer and is provided at one end with an introversion and at another end with a projection in the form of a seed.
摘要翻译： 通过在分离的种子和间隔物之间施加连接器，可以提供具有预定间距的排列的放射性种子和非放射性隔离物的物理相干性。 在第一实施例中，连接器在两端具有向内伸缩的形式，在第二实施例中，连接器还形成间隔件，并且在一端具有内向力并且在另一端处以种子形式的突起设置。
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公开(公告)号：US06572633B1
公开(公告)日：2003-06-03
申请号：US09051414
申请日：1999-03-03
IPC分类号： A61M2900
CPC分类号： A61N5/1002 , A61M25/10 , A61M25/1011 , A61M2025/1013 , A61N2005/1003
摘要： A catheter provided with an elongated tube having channels for the guiding of a radioactive element and for the passage of a guide wire for the catheter as well as fluid under pressure, in which the elongated tube is provided near its distal end on its outer circumference with a recanalization balloon and activatable centering means arranged therein. A by-pass can also be arranged through the recanalization balloon.
摘要翻译： 一种具有细长管的导管，其具有用于引导放射性元件的通道和用于导管的导丝以及压力下的流体的通道，其中细长管在其外周上的远端附近设置， 再通气囊和布置在其中的可激活定心装置。 还可以通过再通气球排列旁路。
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公开(公告)号：US06196964B1
公开(公告)日：2001-03-06
申请号：US09214310
申请日：1999-03-03
IPC分类号： A61M3600
CPC分类号： A61N5/1002 , A61N2005/1025
摘要： A combination of a capsule for incorporating a radioactive source to be applied in brachytherapy and a guidewire, in which the capsule is attached to the guidewire via an adapter, and the adapter comprises a cable or thread with a flexibility greater than that of the guidewire
摘要翻译： 用于结合放射源用于近距离放射治疗的胶囊和导丝，其中胶囊通过适配器附接到导丝，并且适配器包括具有大于导丝的柔性的电缆或线
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公开(公告)号：US6068611A
公开(公告)日：2000-05-30
申请号：US214311
申请日：1999-03-03
CPC分类号： A61N5/1002 , A61M25/10 , A61M25/1011 , A61M2025/1013 , A61M2025/1072 , A61N2005/1003
摘要： A catheter comprising an elongated tube having a first channel for the guiding of a radioactive element and a second channel for the passage of a guide wire for the catheter, in which the elongated tube is provided on its outer circumference near its distal end with temporarily activatable centering means, the centering means being surrounded by recanalization means, and the centering means comprising a plurality of elongated balloons which are inflatable by fluid fed through at least one third channel and, in operation, allow the recanalization means to expand to form an elongated body, with respect to which the first channel is centered.
摘要翻译： PCT No.PCT / NL97 / 00386 Sec。 371日期1999年3月3日 102（e）1999年3月3日PCT PCT 1997年7月4日PCT公布。 第WO98 / 01185号公报 日期1998年1月15日一种导管，其包括具有用于引导放射性元件的第一通道的细长管和用于导管的导丝通过的第二通道，其中细长管设置在其外周上的外周 远端具有临时可激活的对中装置，定心装置被再通风装置包围，并且定心装置包括多个细长的气囊，其可通过流经至少一个第三通道的流体进行充气，并且在操作中允许再通气装置膨胀 以形成细长主体，第一通道相对于该细长主体居中。
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公开(公告)号：US5997462A
公开(公告)日：1999-12-07
申请号：US4632
申请日：1998-01-08
申请人： Edgar German Loffler
发明人： Edgar German Loffler
CPC分类号： A61N5/1007 , A61M25/0113 , A61N2005/1008
摘要： A method and apparatus for treating a lesion (34) of a blood vessel (33) with radiation from a radioactive source (35). A catheter (36) having at least one lumen (56) is placed into the blood vessel (33) with a distal portion (36A) near the lesion (34) and a proximal portion (49) outside of the blood vessel (33). A radiation tube (4) is at least partially placed into the catheter (36) through a lumen (56) such that a juncture (80) is formed between the proximal portion (49) of the catheter (36) and the radiation tube (4). A proximal end of the radiation tube (4) is connected to a drive device (9) for driving the radioactive source (35) through the radiation tube (4) and the catheter (36) to near the lesion (34). An axial translation device (31) is placed at the juncture (80). The axial translation device (31) has a first element (81) fixedly connected in an axial direction (A) to catheter (36) near the proximal portion (49) thereof, a second element (84) fixedly connected in the axial direction (A) to the radiation tube (4) near the juncture (80), and a third element (86) movably connected to the first element (81) and the second element (84). By moving at least one of the elements (81, 84 and 86), a relative axial translation (88) of the catheter (36) and radiation tube (4) is caused for manually positioning the radioactive source (35) near the lesion (34).
摘要翻译： 一种用于利用来自放射源（35）的辐射来治疗血管（33）的病变（34）的方法和装置。 具有至少一个内腔（56）的导管（36）被放置在血管（33）内，远端部分（36A）在病变部分（34）附近，而近端部分（49）位于血管（33）外部， 。 辐射管（4）至少部分地通过内腔（56）放置在导管（36）中，使得在导管（36）的近端部分（49）和辐射管（36）之间形成接合部（80） 4）。 辐射管（4）的近端连接到用于通过辐射管（4）和导管（36）将放射源（35）驱动到病变（34）附近的驱动装置（9）。 轴向平移装置（31）放置在接合部（80）处。 轴向平移装置（31）具有沿轴向方向（A）固定地连接到其近端部分（49）附近的导管（36）的第一元件（81），沿轴向固定连接的第二元件（84） A）到接合部（80）附近的辐射管（4）和可移动地连接到第一元件（81）和第二元件（84）的第三元件（86）。 通过移动元件（81,84和86）中的至少一个，导致导管（36）和辐射管（4）的相对轴向平移（88）用于手动地将放射源（35）放置在病变附近 34）。
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