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    Spacers for use in brachytherapy, radiotherapy, and other medical therapy
    2.
    发明授权
    Spacers for use in brachytherapy, radiotherapy, and other medical therapy 有权
    用于近距离放射治疗，放射治疗和其他医学治疗的间隔物

    公开(公告)号：US08915834B1

    公开(公告)日：2014-12-23

    申请号：US14276691

    申请日：2014-05-13

    Applicant: Eckert & Ziegler Bebig S.A.

    Inventor： Gary A. Lamoureux ,  Warren Johnston ,  Lino Costantini

    IPC: A61M36/00 ,  A61N5/10

    CPC classification number: A61N5/1007 ,  A61N5/10 ,  A61N5/1027 ,  A61N2005/1023 ,  A61N2005/1024

    Abstract: A spacer for use in brachytherapy, and radiotherapy, is formed of an encapsulating material in a generally cylindrical or elongated shape. Regions are formed within the spacer and retaining therapeutic loads, such as radiation sources and/or pharmaceutical therapeutic loads, and/or other substances to treat a patient, such as drug liquids, powder or particles (e.g., microparticles or nanoparticles), with the particles or powders combined with binders, such as polyacrylamide, that are selected to gradually disperse the powder or particles at a desired rate. Such regions can be formed at various locations within the spacer, and can have various shapes depending on the particular design and intended usage. The outer surface of the encapsulating material can optionally include one or more fins, ribs or other physical protuberances or features that improve the fixity of the spacer when implanted within a patient's body.

    Abstract translation: 用于近距离放射治疗和放射治疗的间隔物由大致圆柱形或细长形状的封装材料形成。 区域形成在间隔物内并保持诸如辐射源和/或药物治疗载荷之类的治疗负荷，和/或治疗患者如药物液体，粉末或颗粒（例如，微粒或纳米颗粒）的其它物质，其中 与粘合剂如聚丙烯酰胺组合的颗粒或粉末，其被选择为以期望的速率逐渐分散粉末或颗粒。 这样的区域可以形成在间隔件内的各个位置，并且可以根据具体的设计和预期用途具有各种形状。 封装材料的外表面可以可选地包括一个或多个翅片，肋或其它物理突起或特征，其在植入患者体内时改善间隔物的固定性。

    SPACERS FOR USE IN BRACHYTHERAPY, RADIOTHERAPY, AND OTHER MEDICAL THERAPY
    5.
    发明申请
    SPACERS FOR USE IN BRACHYTHERAPY, RADIOTHERAPY, AND OTHER MEDICAL THERAPY 失效
    用于BRACHYTHERAPY，RADIOTHERAPY和其他医疗治疗的间隔

    公开(公告)号：US20110263923A1

    公开(公告)日：2011-10-27

    申请号：US12963410

    申请日：2010-12-08

    Applicant: Gary A. Lamoureux ,  Warren Johnston ,  Lino Costantini

    Inventor： Gary A. Lamoureux ,  Warren Johnston ,  Lino Costantini

    IPC: A61M36/04

    CPC classification number: A61N5/1007 ,  A61N5/10 ,  A61N5/1027 ,  A61N2005/1023 ,  A61N2005/1024

    Abstract: Spacers for use in brachytherapy, radiotherapy, and other medical therapy, which can be used to improve a patient's outcome, assist in treating difficult cases and/or combine multiple modalities that are currently performed separately into a single procedure. In accordance with an embodiment, a spacer is formed of an encapsulating material in a generally cylindrical or elongated shape. One or more regions are formed within the spacer for receiving and retaining therapeutic loads, such as radiation sources and/or pharmaceutical therapeutic loads, and/or any other substances that a physician might select to treat a patient, such as drug liquids, powder or particles (e.g., microparticles or nanoparticles), with the particles or powders combined with binders, such as polyacrylamide, that are selected to retain and gradually disperse the powder or particles at a desired rate. Such regions can be formed at various locations within the spacer, and can have various shapes depending on the particular design and intended usage, including, for example, bores, end cavities, wells, ports, slots and/or pockets. The outer surface of the encapsulating material can optionally include one or more fins, ribs or other physical protuberances or features that improve the fixity of the spacer when implanted within a patient's body. When implanted into the body, the spacer helps provide proper placement and spacing such as symmetrical and/or asymmetrical placement and spacing of the radiation sources and/or pharmaceutical therapeutic loads.

    Abstract translation: 用于近距离放射治疗，放射治疗和其他医学治疗的间隔器，其可用于改善患者的结果，有助于治疗困难情况和/或组合目前单独进行单个手术的多种模式。 根据实施例，间隔件由大致圆柱形或细长形状的封装材料形成。 一个或多个区域形成在间隔件内，用于接纳和保持诸如辐射源和/或药物治疗载荷之类的治疗负荷，和/或医师可能选择用于治疗患者的任何其它物质，例如药物液体，粉末或 颗粒（例如微粒或纳米颗粒），其中颗粒或粉末与粘合剂如聚丙烯酰胺结合，其被选择以保持并以期望的速率逐渐分散粉末或颗粒。 这样的区域可以形成在间隔件内的各个位置处，并且可以根据具体的设计和预期用途具有各种形状，包括例如孔，端腔，孔，端口，槽和/或袋。 封装材料的外表面可以可选地包括一个或多个翅片，肋或其它物理突起或特征，其在植入患者体内时改善间隔物的固定性。 当植入到体内时，间隔件有助于提供适当的放置和间隔，例如辐射源和/或药物治疗负载的对称和/或不对称放置和间隔。

    Products and methods for brachytherapy
    6.
    发明授权
    Products and methods for brachytherapy 有权
    近距离放射疗法的产品和方法

    公开(公告)号：US08007427B2

    公开(公告)日：2011-08-30

    申请号：US11959687

    申请日：2007-12-19

    Applicant: Jay Reed ,  Mike Rapach ,  Kevin Helle ,  Juliano Oei

    Inventor： Jay Reed ,  Mike Rapach ,  Kevin Helle ,  Juliano Oei

    IPC: A61M36/00

    CPC classification number: A61N5/1027 ,  A61N2005/1023

    Abstract: A radioactive member for use in brachytherapy comprising a hollow elongate bioabsorbable suture member with radioactive seeds and spacer members without different coloration and diameter from the radioactive seeds alternately disposed therein, and methods for the manufacture and the use thereof. The radioactive members may be used in the treatment of, for example, prostate cancer.

    Abstract translation: 一种用于近距离放射治疗的放射性构件，包括具有放射性种子的空心细长生物可吸收缝合构件和与其交替设置的放射性种子没有不同着色和直径的间隔构件及其制造和使用方法。 放射性成分可用于治疗例如前列腺癌。

    Brachytherapy seed
    7.
    发明申请
    Brachytherapy seed 审中-公开
    近距离放射治疗种子

    公开(公告)号：US20110118532A1

    公开(公告)日：2011-05-19

    申请号：US10852407

    申请日：2004-05-24

    Applicant: Edward J. Kaplan

    Inventor： Edward J. Kaplan

    IPC: A61M36/12

    CPC classification number: A61K9/0024 ,  A61K9/0002 ,  A61K41/0038 ,  A61K47/6957 ,  A61K49/0409 ,  A61K51/1282 ,  A61N5/1027 ,  A61N2005/1023 ,  A61N2005/1024 ,  Y10S977/906

    Abstract: A radiopaque brachytherapy seed for implantation into a subject includes a biocompatible component, a therapeutically active component including a non-radioactive drug, and a radiopaque marker. The biocompatible component is (a) physically associated with a therapeutically active component and (b) in contact with the radiopaque marker. The brachytherapy seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge).

    Abstract translation: 用于植入受试者的不透射线近距离放射治疗种子包括生物相容性成分，包括非放射性药物的治疗活性成分和不透射线的标记物。 生物相容性成分是（a）与治疗活性成分物理相关，和（b）与不透射线标记物接触。 近距离放射治疗种子具有适于穿过内径小于约2.7毫米（10度）的针孔的尺寸和形状。

    Brachytherapy spacer
    8.
    发明授权
    Brachytherapy spacer 失效
    近距离放疗

    公开(公告)号：US07749151B2

    公开(公告)日：2010-07-06

    申请号：US11056037

    申请日：2005-02-10

    Applicant: Patrick J. Ferguson

    Inventor： Patrick J. Ferguson

    IPC: A61M36/00

    CPC classification number: A61N5/1027 ,  A61M37/0069 ,  A61N2005/1023

    Abstract: System, including apparatus and methods, for positioning medical material in living tissue using hollow elements that are formed unitarily from a synthetic bioabsorbable material. The hollow elements are optionally filled with a core material and a heat shrink process is performed so that the hollow elements are tightened around the core material.

    Abstract translation: 用于使用由合成的生物可吸收材料整体形成的中空元件将医疗材料定位在生物体组织中的系统，包括装置和方法。 中空元件任选地填充有芯材料，并且进行热收缩工艺，使得中空元件围绕芯材料紧固。

    Brachytherapy apparatus and methods of using same
    9.
    发明授权
    Brachytherapy apparatus and methods of using same 有权
    近距离放射治疗仪及其使用方法

    公开(公告)号：US07736292B2

    公开(公告)日：2010-06-15

    申请号：US11554731

    申请日：2006-10-31

    Applicant: George D. Hermann ,  Doug S. Sutton ,  Gail S. Lebovic ,  Eduardo Chi Sing ,  Robert R. Bowes

    Inventor： George D. Hermann ,  Doug S. Sutton ,  Gail S. Lebovic ,  Eduardo Chi Sing ,  Robert R. Bowes

    IPC: A61M36/12 ,  A61M36/00 ,  A61M36/04 ,  A61N5/00

    CPC classification number: A61N5/1007 ,  A61N5/1014 ,  A61N5/1027 ,  A61N2005/1005 ,  A61N2005/1011 ,  A61N2005/1012 ,  A61N2005/1023 ,  A61N2005/1094

    Abstract: Apparatus, systems and methods for delivering brachytherapy to a target tissue region of a human or other mammalian body. In some embodiments, a flexible brachytherapy device is implanted that includes a therapy delivery portion having one or more radioactive sources securely retained thereto, and a tail portion extending from the therapy delivery portion. Once implanted, the tail portion may extend outside the body, where it may be folded and secured flat against the skin. The device may be removed at therapy completion. Other embodiments of the invention are directed to systems and methods for delivering brachytherapy devices to the body.

    Abstract translation: 用于将近距离放射治疗递送到人或其他哺乳动物身体的靶组织区域的装置，系统和方法。 在一些实施例中，植入柔性近距离放射治疗装置，其包括具有一个或多个可靠地保持在其上的放射源的治疗递送部分和从治疗递送部分延伸的尾部。 一旦植入，尾部可以延伸到身体的外部，在那里它可以被折叠并且平坦地固定在皮肤上。 在治疗完成时可以移除该装置。 本发明的其它实施例涉及用于将近距离放射治疗装置输送到身体的系统和方法。

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