公开(公告)号：US09913716B2

公开(公告)日：2018-03-13

申请号：US15414239

申请日：2017-01-24

申请人： Edwards Lifesciences CardiAQ LLC

发明人： Richard Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Max Pierre Mendez ,  Korey Kline ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Derek Dee Deville

IPC分类号： A61F2/24 ,  A61F2/966 ,  A61F2/07 ,  A61F2/958 ,  A61F2/06 ,  A61F2/848 ,  A61F2/95

CPC分类号： A61F2/243 ,  A61F2/07 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/95 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/061 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2002/8483 ,  A61F2002/8486 ,  A61F2002/9505 ,  A61F2002/9517 ,  A61F2002/9534 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0041 ,  A61F2220/0091 ,  A61F2230/0054 ,  A61F2250/0006 ,  A61F2250/0007 ,  A61F2250/001 ,  A61F2250/006

摘要： A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion can have an actuation mechanism with a motor. The rotatable drive shaft can have a proximal end portion and a distal end portion. The proximal end portion of the rotatable drive shaft can be coupled to the motor, and the distal end portion of the rotatable drive shaft can be configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism can be configured to control and monitor expansion of the prosthetic heart valve and to control and monitor torque of the motor.

公开(公告)号：US20180110618A1

公开(公告)日：2018-04-26

申请号：US15822985

申请日：2017-11-27

申请人： Edwards Lifesciences CardiAQ LLC

发明人： Richard Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, JR. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  Sean McBrayer

IPC分类号： A61F2/24 ,  A61F2/966 ,  A61F2/95

CPC分类号： A61F2/2418 ,  A61B5/021 ,  A61B5/026 ,  A61B5/6862 ,  A61F2/2412 ,  A61F2/2427 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/844 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2002/9534 ,  A61F2002/9665 ,  A61F2220/0041 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2250/0006 ,  A61F2250/0007 ,  A61F2250/001 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/006 ,  A61F2250/0065 ,  A61F2250/0069

摘要： An assembly includes a prosthetic heart valve and a delivery apparatus. The prosthetic heart valve has a plurality of pivotably connected struts and one or more adjustable elements rotatably coupled to the struts. Rotating the adjustable elements in a first direction relative to the struts radially expands the prosthetic heart valve. Rotating the adjustable elements in a second direction relative to the struts radially contracts the prosthetic heart valve. The delivery apparatus includes one or more motors, one or more drive wires coupled to the motors, and a memory. The drive wires are coupled to the adjustable elements of the prosthetic heart valve. The motors are configured to rotate the drive wires and the adjustable elements to expand and contract the prosthetic heart valve. The memory is configured for storing one or more characteristics of the motors, the drive wires, or the prosthetic heart valve.

公开(公告)号：US20160367360A1

公开(公告)日：2016-12-22

申请号：US15189786

申请日：2016-06-22

申请人： Edwards Lifesciences CardiAQ, LLC

发明人： Richard Cartledge ,  Derek Dee Deville ,  Kevin W. Smith ,  James L. Greene ,  Jorge Jimenez

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2436 ,  A61F2220/0016 ,  A61F2230/0006 ,  A61F2230/0034 ,  A61F2230/0052 ,  A61F2250/001 ,  A61F2250/0039 ,  A61F2250/0048

摘要： A mitral valve implant includes a force-expanding mitral valve lattice having an interior orifice and a self-expanding valve trampoline attached at the interior orifice of the force-expanding mitral valve lattice. The mitral valve lattice is self-expandable to a first configuration and force expandable from the first configuration to a second configuration. The configurations can be circular or D-shaped. The mitral valve lattice comprises jack screws adjusting configurations of the mitral valve lattice. The valve trampoline has a cylindrical central region comprising valve leaflets. An outwardly flaring implant skirt is attached to the mitral valve lattice exterior. Wall-retaining wires are attached to the mitral valve lattice, are petal-shaped, and have a pre-set, radially outward, memory shape. The wires and skirt impart a force on a respective side of the native mitral valve when the mitral valve lattice is expanded within an annulus of the native mitral valve.

摘要翻译： 二尖瓣植入物包括力扩张二尖瓣网格，其具有连接在力扩张二尖瓣网格的内孔处的内孔和自膨胀阀蹦床。 二尖瓣网格可自膨胀至第一构型，并且力可从第一构型扩展至第二构型。 配置可以是圆形或D形。 二尖瓣格子包括调整二尖瓣格结构的千斤顶螺钉。 阀蹦床具有包括瓣叶的圆柱形中心区域。 向外扩张的植入物裙缘连接到二尖瓣格架外部。 护壁线连接到二尖瓣格子，呈花瓣状，并且具有预设的径向向外的记忆形状。 当二尖瓣网格在天然二尖瓣的环形区域内扩张时，电线和裙部在天然二尖瓣的相应侧上施加力。

公开(公告)号：US10226335B2

公开(公告)日：2019-03-12

申请号：US15189786

申请日：2016-06-22

申请人： Edwards Lifesciences CardiAQ, LLC

发明人： Richard Cartledge ,  Derek Dee Deville ,  Kevin W. Smith ,  James L. Greene ,  Jorge Jimenez

IPC分类号： A61F2/24

摘要： A mitral valve implant includes a force-expanding mitral valve lattice having an interior orifice and a self-expanding valve trampoline attached at the interior orifice of the force-expanding mitral valve lattice. The mitral valve lattice is self-expandable to a first configuration and force expandable from the first configuration to a second configuration. The configurations can be circular or D-shaped. The mitral valve lattice comprises jack screws adjusting configurations of the mitral valve lattice. The valve trampoline has a cylindrical central region comprising valve leaflets. An outwardly flaring implant skirt is attached to the mitral valve lattice exterior. Wall-retaining wires are attached to the mitral valve lattice, are petal-shaped, and have a pre-set, radially outward, memory shape. The wires and skirt impart a force on a respective side of the native mitral valve when the mitral valve lattice is expanded within an annulus of the native mitral valve.

公开(公告)号：US20180104077A1

公开(公告)日：2018-04-19

申请号：US15793867

申请日：2017-10-25

申请人： Edwards Lifesciences CardiAQ LLC

发明人： Richard Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, JR. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  Sean McBrayer

IPC分类号： A61F2/93 ,  A61F2/24 ,  A61F2/82 ,  A61F2/07 ,  A61F2/95

CPC分类号： A61F2/93 ,  A61F2/07 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/82 ,  A61F2/844 ,  A61F2002/075 ,  A61F2002/825 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2002/9534 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0033 ,  A61F2220/0041 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2250/0007 ,  A61F2250/0008 ,  A61F2250/001 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/006 ,  A61F2250/0065

摘要： A delivery apparatus comprises a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism and a display. The actuation mechanism includes a motor and one or more actuators. The rotatable drive shaft has a proximal end portion and a distal end portion. The proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve, and the display is configured to display a diameter of the prosthetic heart valve.

公开(公告)号：US09814611B2

公开(公告)日：2017-11-14

申请号：US13772203

申请日：2013-02-20

申请人： Edwards Lifesciences CardiAQ LLC

发明人： Richard Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  Sean McBrayer

IPC分类号： A61F2/82 ,  A61F2/93 ,  A61F2/07 ,  A61F2/24 ,  A61F2/95

CPC分类号： A61F2/93 ,  A61F2/07 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/243 ,  A61F2/2439 ,  A61F2/82 ,  A61F2002/075 ,  A61F2002/825 ,  A61F2002/9511 ,  A61F2002/9534 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0041 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2250/0007 ,  A61F2250/001 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/006 ,  A61F2250/0065

摘要： Sealable and repositionable implant devices are provided to increase the ability of endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes a self-expanding stent of a shape-memory material set to a given shape. The stent has a wall with a portion having a first thickness and a second portion having a thickness greater than the first. The second portion defines a key-hole shaped longitudinal drive orifice. The implant includes a selectively adjustable assembly having adjustable elements and being operable to force a configuration change in at least a portion of the self-expanding stent. The adjustable elements have a part rotatably disposed within the longitudinal drive orifice.

公开(公告)号：US10238514B2

公开(公告)日：2019-03-26

申请号：US15793867

申请日：2017-10-25

申请人： Edwards Lifesciences CardiAQ LLC

发明人： Richard Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  Sean McBrayer

IPC分类号： A61F2/24 ,  A61F2/966 ,  A61F2/93 ,  A61F2/844 ,  A61F2/07 ,  A61F2/82 ,  A61F2/95

摘要： A delivery apparatus comprises a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism and a display. The actuation mechanism includes a motor and one or more actuators. The rotatable drive shaft has a proximal end portion and a distal end portion. The proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve, and the display is configured to display a diameter of the prosthetic heart valve.