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公开(公告)号：US12023245B2
公开(公告)日：2024-07-02
申请号：US17678878
申请日：2022-02-23
发明人： Garrett Dallas Johnson , David Robert Landon , Lindsay Lam , Glen T. Rabito , Alexander H. Cooper
CPC分类号： A61F2/2433 , A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2002/9511 , A61F2/9517 , A61F2002/9665 , A61F2230/0054 , A61F2230/0065 , A61F2250/0097 , A61F2250/0098 , A61M2025/1093
摘要： Devices, systems and methods are described for implantation of a prosthesis within a lumen or body cavity and delivery systems for delivering the prosthesis to a location for implantation. A delivery system can include a tether connected to a single directional handle knob for release of the prosthesis within the lumen or body cavity and retraction of the tether towards the handle.
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公开(公告)号：US20240099868A1
公开(公告)日：2024-03-28
申请号：US18529333
申请日：2023-12-05
CPC分类号： A61F2/954 , A61F2/07 , A61F2002/9528
摘要： An assembly includes an implant and a control lead. The implant includes a tubular implant body, a circumferentially adjustable sealing collar coupled to the implant body, a rotatable sealer gear coupled to the sealing collar and configured to adjust the circumference of the sealing collar, and a locking member having a locked state and an unlocked state. The control lead is configured for rotating the locking member and moving the locking member from the locked state to the unlocked state. In the locked state, rotating the control lead does not adjust the circumference of the sealing member. In the unlocked state, rotating the control lead in a first direction rotates the locking member and the sealer gear and circumferentially expands the sealing collar. In the unlocked state, rotating the control lead in a second direction rotates the locking member and the sealer gear and circumferentially contracts the sealing collar.
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公开(公告)号：US11707356B2
公开(公告)日：2023-07-25
申请号：US17118382
申请日：2020-12-10
发明人： Richard George Cartledge , Kevin W. Smith , Thomas O. Bales, Jr. , Derek Dee Deville , Korey Kline , Max Pierre Mendez , Matthew A. Palmer , Michael Walter Kirk , Carlos Rivera , Eric Petersen , M. Sean McBrayer
CPC分类号： A61F2/2418 , A61B5/6862 , A61F2/243 , A61F2/2412 , A61F2/2436 , A61F2/2439 , A61F2/844 , A61F2/95 , A61B5/021 , A61B5/026 , A61F2/2427 , A61F2/9517 , A61F2002/9505 , A61F2002/9511 , A61F2002/9534 , A61F2002/9665 , A61F2220/0041 , A61F2220/0075 , A61F2220/0091 , A61F2250/001 , A61F2250/0006 , A61F2250/006 , A61F2250/0007 , A61F2250/0018 , A61F2250/0039 , A61F2250/0065 , A61F2250/0069
摘要： A prosthetic heart valve includes a frame, a valve, and an expansion element. The frame is movable between contracted and expanded configurations and includes first struts and second struts non-hingedly coupled together. The second struts are configured to pivot relative to the first struts as the frame moves between the contracted and expanded configurations. The valve is coupled to the frame and includes leaflets. The expansion element extends through a lumen of the first struts. The expansion element is slidable relative to the lumen of the first struts and is configured to move the frame incrementally from the contracted configuration and the expanded configuration and from the expanded configuration to the contracted configuration.
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公开(公告)号：US11633279B2
公开(公告)日：2023-04-25
申请号：US17207327
申请日：2021-03-19
发明人： Glen T. Rabito , Jeremy Brent Ratz , Arshad Quadri , Lindsay Lam , David Robert Landon , Garrett Dallas Johnson
IPC分类号： A61F2/24
摘要： Methods for delivering a replacement heart valve include advancing a delivery system through a femoral vein and into the atrium of a heart, wherein the delivery system includes an outer sheath assembly, a mid shaft assembly and an inner assembly. The outer sheath assembly and the mid shaft assembly are adapted to retain the replacement heart valve in a radially compacted state over the inner assembly. The outer sheath assembly is retracted to allow a plurality of distal anchors to self-expand while a portion of the replacement heart valve remains retained in a compacted state by the mid shaft assembly. The distal anchors are positioned to engage one or more native leaflets and the retained portion of the replacement heart valve is then released and allowed to fully expand for implanting the replacement heart valve within the native valve.
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公开(公告)号：US11376119B2
公开(公告)日：2022-07-05
申请号：US16601054
申请日：2019-10-14
发明人： Arshad Quadri , J. Brent Ratz
摘要： A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.
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公开(公告)号：US11324591B2
公开(公告)日：2022-05-10
申请号：US16783868
申请日：2020-02-06
发明人： J. Brent Ratz , Arshad Quadri , Luca Pesce
IPC分类号： A61F2/24
摘要： A prosthesis can comprise an expandable frame, a plurality of distal anchors and a plurality of proximal anchors. The anchors can extend outwardly from the frame. The frame can be configured to radially expand and contract for deployment within a body cavity. The frame and anchors can have one of many different shapes and configurations. For example, when the frame is in an expanded configuration, the frame can have a larger cross-sectional dimension in a middle portion of the frame and a smaller cross-sectional dimension in a proximal portion and a distal portion of the frame, wherein the middle portion is between the proximal and distal portions. As another example, the anchors can have looped ends, the entire anchor may loop out from the frame.
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公开(公告)号：US11278405B2
公开(公告)日：2022-03-22
申请号：US16781619
申请日：2020-02-04
发明人： Garrett Dallas Johnson , David Robert Landon , Lindsay Lam , Glen T. Rabito , Alexander H. Cooper
摘要： Devices, systems and methods are described for implantation of a prosthesis within a lumen or body cavity and delivery systems for delivering the prosthesis to a location for implantation. A delivery system can include a tether connected to a single directional handle knob for release of the prosthesis within the lumen or body cavity and retraction of the tether towards the handle.
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公开(公告)号：US20210205083A1
公开(公告)日：2021-07-08
申请号：US17207327
申请日：2021-03-19
发明人： Glen T. Rabito , J. Brent Ratz , Arshad Quadri , Lindsay Lam , David Robert Landon , Garrett Dallas Johnson
IPC分类号： A61F2/24
摘要： Methods for delivering a replacement heart valve include advancing a delivery system through a femoral vein and into the atrium of a heart, wherein the delivery system includes an outer sheath assembly, a mid shaft assembly and an inner assembly. The outer sheath assembly and the mid shaft assembly are adapted to retain the replacement heart valve in a radially compacted state over the inner assembly. The outer sheath assembly is retracted to allow a plurality of distal anchors to self-expand while a portion of the replacement heart valve remains retained in a compacted state by the mid shaft assembly. The distal anchors are positioned to engage one or more native leaflets and the retained portion of the replacement heart valve is then released and allowed to fully expand for implanting the replacement heart valve within the native valve.
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公开(公告)号：US11045313B2
公开(公告)日：2021-06-29
申请号：US16247403
申请日：2019-01-14
IPC分类号： A61F2/24
摘要： A prosthesis for placement within a native mitral valve includes an expandable frame having locking tabs disposed along a proximal end. A plurality of distal anchors are disposed along a distal end of the frame. Each distal anchor is provided with a cushion cover. An outer fabric member surrounds the frame and may extend outwardly from the frame in an expanded condition for providing an improved seal in the region of a mitral annulus. A valve body is positioned within an interior of the expandable from for allowing blood flow in only one direction. In preferred embodiments, the cushions are positioned over enlarged head portions of the distal anchors for further reducing trauma on surrounding tissue.
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公开(公告)号：US20210169671A1
公开(公告)日：2021-06-10
申请号：US17182046
申请日：2021-02-22
摘要： A method of implanting a prosthetic implant includes advancing a prosthetic implant into a patient's vasculature with a delivery apparatus, the delivery apparatus comprising a catheter and a control lead, the catheter including a lumen extending therethrough, the control lead extending through the lumen of the catheter, the prosthetic implant comprising an implant body, a seal extending radially outwardly from the implant body, and a locking bar coupled to the implant body and releasably coupled to the control lead, the locking bar radially offset relative to the central longitudinal axis of the implant body. The method further includes rotating the control lead of the delivery apparatus in a first direction relative to the catheter such that the locking bar rotates in the first direction relative to the implant body and the implant body expands radially from a first radially compressed state to a first radially expanded state.
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