Patent search ap:("Exosome Diagnostics Page Inc.") AND inv:"James HURLEY"

1.

发明申请
PLASMA-BASED DETECTION OF ANAPLASTIC LYMPHOMA KINASE (ALK) NUCLEIC ACIDS AND ALK FUSION TRANSCRIPTS AND USES THEREOF IN DIAGNOSIS AND TREATMENT OF CANCER 审中-公开

公开(公告)号：US20190093172A1

公开(公告)日：2019-03-28

申请号：US16092358

申请日：2017-04-17

Applicant: Exosome Diagnostics, Inc.

Inventor： Johan Karl Olov SKOG , Mikkel NOERHOLM , James HURLEY , Elena CASTELLANOS-RIZALDOS , Kay BRINKMAN

IPC: C12Q1/6886 , C12N15/10 , C12Q1/686 , G16H50/20

Abstract: The present invention relates generally to the field of biomarker analysis, particularly determining gene expression signatures from biological samples, including plasma samples.

2.

发明公开
USE OF MICROVESICLE SIGNATURE FOR THE DIAGNOSIS AND TREATMENT OF KIDNEY TRANSPLANT REJECTION 审中-公开

公开(公告)号：US20230203587A1

公开(公告)日：2023-06-29

申请号：US17928452

申请日：2021-05-28

Applicant: Exosome Diagnostics, Inc. , The Brigham and Women's Hospital, Inc.

Inventor： Johan SKOG , Vasisht TADIGOTLA , James HURLEY , Jamil AZZI

IPC: C12Q1/6883 , C12Q1/686

CPC classification number: C12Q1/6883 , C12Q1/686 , C12Q2600/118 , C12Q2600/158

Abstract: The present disclosure relates to methods of identifying and treating kidney rejection in a subject comprising analyzing microvesicular RNA, cell-free DNA or the combination of microvesicular and cell-free DNA.”

3.

发明申请
METHODS FOR DEVELOPING URINE BIOMARKERS AND FOR DETECTING BLADDER CANCER 有权

公开(公告)号：US20210230701A1

公开(公告)日：2021-07-29

申请号：US15734363

申请日：2019-06-06

Applicant: Exosome Diagnostics, Inc.

Inventor： Robert KITCHEN , Elena CASTELLANOS-RIZALDOS , Mia SHER , James HURLEY , Dalin CHAN , Georg STOLL , Wei YU , Johan SKOG

IPC: C12Q1/6886

Abstract: The present disclosure relates to methods for detecting and treating bladder cancer in a subject using the gene expression level measurements from exosomes derived from the subject.

4.

发明申请
SEQUENCING OF NUCLEIC ACIDS ASSOCIATED WITH EXOSOMAL ISOLATION FROM PATIENTS WITH GLIOBLASTOMA MULTIFORME 审中-公开

公开(公告)号：US20200224245A1

公开(公告)日：2020-07-16

申请号：US16631603

申请日：2018-07-18

Applicant: Exosome Diagnostics, Inc.

Inventor： Robert KITCHEN , Michael VALENTINO , Johan SKOG , Vasisht TADIGOTLA , Dalin CHAN , Sudipto CHAKRABORTTY , James HURLEY

IPC: C12Q1/686 , C12Q1/6806 , C12Q1/6886 , C12Q1/6851

Abstract: The present disclosure relates to methods for providing a clinical assessment of a subject in need thereof using the gene expression level measurements from exosomes derived from the subject.

5.

发明申请
USE OF MICROVESICLE SIGNATURES IN THE IDENTIFICATION AND TREATMENT OF RENAL DISORDERS 有权

公开(公告)号：US20250163510A1

公开(公告)日：2025-05-22

申请号：US18839547

申请日：2023-02-21

Applicant: Exosome Diagnostics, Inc. , The Brigham and Women's Hospital, Inc.

Inventor： Johan Karl Olov SKOG , Brian C. HAYNES , Elliot HALLMARK , James HURLEY , Jamil AZZI

IPC: C12Q1/6883 , G01N33/68

Abstract: The present disclosure relates to methods of identifying and treating kidney rejection in a subject comprising analyzing RNA, including microvesicular RNA.

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