公开(公告)号：US20140296666A1

公开(公告)日：2014-10-02

申请号：US14304690

申请日：2014-06-13

Applicant: GIVEN IMAGING LTD.

Inventor： ELISHA RABINOVITZ ,  Zvika GILAD ,  Amit PASCAL ,  Yaniv BIRNBOIM ,  Gavriel J. IDDAN ,  Daniel GAT ,  Hagai KRUPNIK ,  Ori BRAUN ,  Dan ROTTENBERG ,  Omer SHEZIFI ,  Yosi PESIS ,  Dima PINHASOV ,  Evgeny KAPILOV ,  Nir LILACH ,  Eliahu ELIACHAR ,  Oren COHEN ,  Daniel GAMZU

IPC: A61B5/1459

CPC classification number: A61B5/1459 ,  A61B1/041 ,  A61B1/063 ,  A61B1/0684 ,  A61B5/0084 ,  A61B5/073

Abstract: In-vivo devices, systems and methods for the detection of blood within in-vivo bodily fluids. The methods include irradiating in-vivo fluids passing through a gap in a housing of an in-vivo device introduced to the GI tract of a subject with a plurality of illumination sources positioned on a first side of a gap; detecting with at least one light detector positioned on the opposite side of the gap and facing the illumination sources, light irradiated by the illumination sources; transmitting a plurality of values representing the light detected over time; converting these values to blood concentration values over time, and comparing the blood concentration values to a predetermined threshold value. Based on the comparison, the method includes determining the type of bleeding profile, such that if a plurality of blood concentration values measured consecutively is above the threshold value, the bleeding profile indicates bleeding.

Abstract translation: 用于检测体内体液内的血液的体内装置，系统和方法。 所述方法包括：照射通过定位在间隙的第一侧上的多个照明源的通过被导入到对象的胃肠道的体内装置的壳体中的间隙的体内流体; 用位于所述间隙的相对侧上并且面对所述照明源的至少一个光检测器检测由所述照明源照射的光; 发送表示随时间检测到的光的多个值; 将这些值随时间转换为血液浓度值，并将血液浓度值与预定阈值进行比较。 基于比较，该方法包括确定出血分布的类型，使得如果连续测量的多个血液浓度值高于阈值，则出血分布指示出血。

公开(公告)号：US20140275860A1

公开(公告)日：2014-09-18

申请号：US14212304

申请日：2014-03-14

Applicant: Given Imaging Ltd.

Inventor： Dan ROTTENBERG ,  Robert Sayegh

IPC: A61B5/02 ,  A61B1/06 ,  A61B1/04 ,  A61B5/00 ,  A61B5/07

CPC classification number: A61B5/02042 ,  A61B1/00087 ,  A61B1/041 ,  A61B1/06 ,  A61B5/0084 ,  A61B5/073 ,  A61B5/4233 ,  A61B5/4238 ,  A61B5/4255 ,  A61B2562/162 ,  A61B2562/18

Abstract: Devices and a system for detection of blood within in-vivo fluids are provided. A device comprises a housing that includes a gap. The gap has at least one opening through which in-vivo fluids may enter and/or exit the gap. The device further comprises an illumination source for illuminating the in-vivo fluids in the gap, a light detector for detecting light which passes through the in-vivo fluids in the gap, and flexible fins disposed on the housing in the vicinity of the gap's opening for covering the opening when the fins are folded and for pumping fluids into and out of the opening by repeated closure and opening of the opening by the fins, due to repeated peristaltic waves. This pumping effect may lead to continuous flow of fluids into and out of the opening and thus into and out of the gap of the device.

Abstract translation: 提供了用于检测体内流体内的血液的装置和系统。 一种装置包括包括间隙的壳体。 间隙具有至少一个开口，体内流体可通过该开口进入和/或离开间隙。 该装置还包括用于照射间隙中的体内流体的照明源，用于检测通过间隙中的体内流体的光的光检测器，以及设置在间隙开口附近的壳体上的柔性翅片 用于当翅片被折叠时覆盖开口，并且由于重复的蠕动波，通过由翅片重复地关闭和打开开口来将流体泵入和流出开口。 这种泵送效应可能导致流体连续流入和流出开口，从而进入和流出装置的间隙。