公开(公告)号：US12076167B2

公开(公告)日：2024-09-03

申请号：US16927233

申请日：2020-07-13

Applicant: Edwards Lifesciences Corporation

Inventor： Feras Al Hatib ,  Zhongping Jian ,  Sai Prasad Buddi

IPC: A61B5/021 ,  A61B5/00 ,  A61B5/02 ,  G16H50/30

CPC classification number: A61B5/7275 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/7239 ,  A61B5/746 ,  G16H50/30 ,  A61B5/02042

Abstract: A system having a processor obtain a digital hemodynamic data from a hemodynamic sensor, obtain one or more vital sign parameters characterizing vital sign data from the digital hemodynamic data, derive differential parameters based on the one or more vital sign parameters, generate combinatorial parameters using the one or more vital sign parameters and the differential parameters, determine a risk score corresponding to a probability of a future hypotension event for the living subject based on a weighted combination of a plurality of hypotension profiling parameters including the one or more vital sign parameters characterizing vital sign data, the differential parameters and the combinatorial parameters, and invoke a sensory alarm if the risk score satisfies a predetermined risk criterion.

公开(公告)号：US12076120B2

公开(公告)日：2024-09-03

申请号：US16934805

申请日：2020-07-21

Applicant: Mayo Foundation for Medical Education and Research ,  The Government of The United States, as Represented by the Secretary of the Army

Inventor： Robert W. Techentin ,  Timothy B. Curry ,  Michael J. Joyner ,  Clifton R. Haider ,  David R. Holmes, III ,  Christopher L. Felton ,  Barry K. Gilbert ,  Charlotte Sue Van Dorn ,  William A. Carey ,  Victor A. Convertino

IPC: A61B5/02 ,  A61B5/00 ,  A61B5/021 ,  A61B5/024 ,  G06N3/004 ,  G06N3/008

CPC classification number: A61B5/02042 ,  A61B5/0004 ,  A61B5/02028 ,  A61B5/02108 ,  A61B5/02416 ,  A61B5/7264 ,  A61B5/7275 ,  G06N3/004 ,  G06N3/008

Abstract: In accordance with some embodiments, systems, methods, and media for estimating compensatory reserve and predicting hemodynamic decompensation using physiological data are provided. In some embodiments, a system for estimating compensatory reserve is provided, the system comprising: a processor programmed to: receive a blood pressure waveform of a subject; generate a first sample of the blood pressure waveform with a first duration; provide the sample as input to a trained CNN that was trained using samples of the first duration from blood pressure waveforms recorded from subjects while decreasing the subject's central blood volume, each sample being associated with a compensatory reserve metric; receive, from the trained CNN, a first compensatory reserve metric based on the first sample; and cause information indicative of remaining compensatory reserve to be presented.

公开(公告)号：US20240245345A1

公开(公告)日：2024-07-25

申请号：US18560189

申请日：2022-05-10

Applicant: Flashback Technologies, Inc.

Inventor： John Jedziniak ,  Abhishek Jaiantilal ,  Mike Halperin

IPC: A61B5/00 ,  A61B5/02 ,  A61B5/0205 ,  G16H20/10 ,  G16H40/63 ,  G16H50/20 ,  G16H50/30 ,  G16H50/50

CPC classification number: A61B5/412 ,  A61B5/02028 ,  A61B5/02042 ,  A61B5/02055 ,  A61B5/4839 ,  A61B5/7246 ,  A61B5/7275 ,  A61B5/742 ,  G16H20/10 ,  G16H40/63 ,  G16H50/20 ,  G16H50/30 ,  G16H50/50

Abstract: Novel tools and techniques are provided for detecting and differentiating sepsis are provided A system includes one or more sensors configured to obtain non-invasive physiological data from a patient, and estimate a compensatory reserve index based on the physiological data. A computer system may determine, based on the compensatory reserve index, whether the patient is septic by applying a sepsis model configured to relate hemodynamic parameters over time to a determination of sepsis. Hemodynamic parameters may include a compensatory reserve index (CRI).

公开(公告)号：US20240065793A1

公开(公告)日：2024-02-29

申请号：US17897172

申请日：2022-08-28

Applicant: SURGIBOX INC.

Inventor： Mike Horia Mihail Teodorescu

IPC: A61B46/23 ,  A61B5/02

CPC classification number: A61B46/23 ,  A61B5/02042 ,  A61B2046/205 ,  A61B2046/236 ,  A61B2562/0247 ,  A61B2562/043

Abstract: A blood-management-system for collecting blood from a surgical-site of a patient and for measuring the patient's blood loss is disclosed. The blood management system includes a drape configured to be disposed on the patient. The drape further includes an adhesive layer forming a seal between the drape and a region surrounding the surgical site. The blood management-system further includes a drape-collector disposed on the drape, in the proximity of the surgical-site. The drape-collector is configured to collect blood spilled on the surgical-site-layer, to store blood, and to evaluate the quantity of blood collected in the drape-collector. The blood-management-system further includes blood-containers configured to receive fluids from the drape, to store the fluids, and to measure the fluids quantity. The blood-management-system further includes a computing system configured to receive information from the drape-collector and the blood-container and to evaluate the amount of blood lost by the patient.

公开(公告)号：US11890079B1

公开(公告)日：2024-02-06

申请号：US17156573

申请日：2021-01-23

Applicant: Zynex Monitoring Solutions Inc.

Inventor： Thomas Sandgaard

IPC: A61B5/02 ,  A61B5/0205 ,  A61B5/00 ,  A61B5/026 ,  A61B5/0531

CPC classification number: A61B5/02042 ,  A61B5/02055 ,  A61B5/4848 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/746 ,  A61B5/7425 ,  A61B5/026 ,  A61B5/0531 ,  A61B5/443 ,  A61B5/7435 ,  A61B2505/05 ,  A61B2562/029

Abstract: Noninvasive methods and apparatus for detecting blood volume imbalances in a mammalian subject are disclosed. The method includes obtaining baseline measurements of at least three physiological parameters from a subject wherein the parameters are selected from the group consisting of heart rate, electrical body impedance, skin temperature, perfusion index, peripheral blood flow and skin humidity. Measurements of electrical body impedance, skin temperature, perfusion index, peripheral blood flow and skin humidity are taken at one or more extremities of the subject such as the calf, ankle, forearm, thigh, fingers and toes. The physiological parameters for which baseline measurements were obtained are then monitored to detect changes from the baseline measurements that indicate blood volume imbalances. A preferred embodiment comprises computing a baseline blood volume index from the baseline value measurements of each parameter to be monitored and then carrying out the step of monitoring by obtaining real time (current) value measurements of these parameters which are inputted into an algorithm which computes a real time (current) blood volume index based upon the differences between the baseline and real time (current) value measurements.

公开(公告)号：US11857443B2

公开(公告)日：2024-01-02

申请号：US16941867

申请日：2020-07-29

Applicant: Board of Regents of the University of Nebraska

Inventor： Jason N. MacTaggart ,  Alexey Kamenskiy

IPC: A61F2/958 ,  A61F2/07 ,  A61B17/12 ,  A61F2/95 ,  A61B5/00 ,  A61B5/02 ,  A61B17/00 ,  A61B5/0215 ,  A61B5/024 ,  A61B5/145 ,  A61B5/0205 ,  A61F2/06

CPC classification number: A61F2/958 ,  A61B5/02 ,  A61B5/02042 ,  A61B5/6862 ,  A61B17/12036 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12118 ,  A61B17/12136 ,  A61F2/07 ,  A61B5/024 ,  A61B5/02055 ,  A61B5/02158 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/6853 ,  A61B2017/00017 ,  A61B2017/00022 ,  A61F2/9522 ,  A61F2002/061 ,  A61F2002/077 ,  A61F2002/9528 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2250/001 ,  A61F2250/0002 ,  A61F2250/0003 ,  A61F2250/0024 ,  A61F2250/0039 ,  A61F2250/0059 ,  A61F2250/0069 ,  A61F2250/0096

Abstract: Some implementations of an endovascular device include a stent graft with an expandable tubular metallic frame and a covering material disposed on at least a portion of the metallic frame. The stent graft defines a lumen therethrough. In a particular embodiment, a first balloon is disposed around an outer periphery of the stent graft, a second balloon is disposed around the outer periphery of the stent graft and spaced apart from the first balloon, and a third balloon is disposed within the stent graft lumen between the first balloon and the second balloon. The third balloon can be inflated to fully or partially occlude the lumen. The first and second balloons can be individually inflated to fully or partially shunt blood flow from a blood vessel through the stent graft. In some embodiments, sensors and an automated control unit are included to automate the operations of the endovascular device.

公开(公告)号：US20230401735A1

公开(公告)日：2023-12-14

申请号：US18238620

申请日：2023-08-28

Applicant: Gauss Surgical Inc.

Inventor： Siddarth Satish ,  Kevin J. Miller ,  Ali Zandifar

IPC: G06T7/62 ,  G06F18/00 ,  G06T5/00

CPC classification number: G06T7/62 ,  G06F18/00 ,  G06T5/00 ,  A61B5/02042

Abstract: A method for estimating extracorporeal blood volume in at least a portion of a fluid canister. A light source may be activated, and an image of the fluid canister is captured with an optical sensor. The image may be a color frame of a video stream. A color-related feature is extracted from at least a portion of the image. A concentration of hemoglobin is estimated based on the extracted color-related feature. A fluid level of fluid within the fluid canister may be estimated from the image. Extracorporeal blood volume based on the estimated concentration of hemoglobin and a fluid volume or the estimated fluid level. The estimated extracorporeal blood volume is displayed on a display. The estimated extracorporeal blood volume and the estimated fluid level may be monitored over time. The optical sensor may be disposed on a handheld mobile device mounted to a side of the fluid canister.

公开(公告)号：US20230401649A1

公开(公告)日：2023-12-14

申请号：US18451599

申请日：2023-08-17

Applicant: Theator Inc.

Inventor： Tamir WOLF ,  Dotan ASSELMANN

IPC: G06Q40/08 ,  A61B90/00 ,  A61B34/00 ,  A61B34/37 ,  G16H20/40 ,  G16H50/70 ,  G16H50/20 ,  G16H30/40 ,  G16H70/20 ,  G16H15/00 ,  A61B34/30 ,  G16H40/63 ,  A61B17/00 ,  G16H50/30 ,  G06F16/71 ,  A61B34/10 ,  G16H40/20 ,  G16H30/20 ,  A61B5/02 ,  A61B5/103 ,  A61B5/00 ,  G06Q10/0631 ,  G06V20/20 ,  G06V20/40 ,  G06V20/52 ,  A61B90/92 ,  G06F16/735 ,  G11B27/10 ,  A61B1/00

CPC classification number: G06Q40/08 ,  A61B90/37 ,  A61B34/25 ,  A61B34/70 ,  A61B34/37 ,  G16H20/40 ,  G16H50/70 ,  G16H50/20 ,  G16H30/40 ,  G16H70/20 ,  G16H15/00 ,  A61B34/30 ,  A61B90/06 ,  A61B90/361 ,  G16H40/63 ,  A61B17/00 ,  G16H50/30 ,  G06F16/71 ,  A61B34/10 ,  G16H40/20 ,  G16H30/20 ,  A61B5/02042 ,  A61B5/1032 ,  A61B5/7267 ,  A61B5/7275 ,  G06Q10/06312 ,  G06V20/20 ,  G06V20/40 ,  G06V20/41 ,  G06V20/49 ,  G06V20/52 ,  A61B90/92 ,  G06F16/735 ,  A61B5/746 ,  G11B27/10 ,  A61B1/000094 ,  A61B1/000096 ,  A61B2090/0807 ,  A61B2034/302 ,  A61B2090/065 ,  A61B2017/0011 ,  A61B2017/00119 ,  A61B2034/104 ,  A61B2034/252 ,  A61B2505/05 ,  A61B2034/254 ,  A61B2034/256 ,  G06V20/44 ,  G06V2201/034 ,  G06V40/10

Abstract: Systems and methods for updating a predicted outcome during a surgical procedure are disclosed. The system may include at least one processor configured to perform operations that include receiving, from at least one image sensor, image data associated with a first event and image data associated with a second event during a surgical procedure. Operations may include determining, based on received image data associated with the first event, a predicted outcome associated with the surgical procedure. Operations may include determining, based on the received image data associated with the second event, a change in the predicted outcome, causing the predicted outcome to drop below a threshold. Operations may include accessing a data structure of image-related data based on prior surgical procedures, identifying, based on the data structure, a recommended remedial action, and outputting the recommended remedial action.

公开(公告)号：US20230355109A1

公开(公告)日：2023-11-09

申请号：US18028532

申请日：2021-09-27

Applicant: The Trustees of Dartmouth College

Inventor： Norman Alan Paradis ,  Ryan J. Halter ,  Jonathan T. Elliott ,  Vikrant S. Vaze ,  Ethan K. Murphy

IPC: A61B5/02 ,  A61B5/0536 ,  A61B5/00

CPC classification number: A61B5/02042 ,  A61B5/0536 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/0075 ,  A61B5/6823 ,  A61B5/6828 ,  A61B5/6824

Abstract: This invention provides a system and method that employs multiple measurements of various, relevant tissue states of a patient to detect and predict OH and similar conditions. These multi anatomic measurements are transformed by a multivariate algorithm to outputs that convey the diagnostic and prognostic risk of the disease of interest. This novel, multiple-measurement technique avoids use of a single measurement, which is generally unlikely to adequately extract sufficient information to drive a clinically useful test in the setting of complex system disease. The system and method herein thereby allows automated monitoring of currently stable patients who, are known or suspected to have OH and/or similar internal conditions on a substantially continuous basis.

公开(公告)号：US11801002B2

公开(公告)日：2023-10-31

申请号：US16823482

申请日：2020-03-19

Applicant: DAXOR CORP.

Inventor： Jonathan Feldschuh

IPC: A61B5/157 ,  A61B5/0205 ,  A61B5/00 ,  A61B5/029 ,  A61B5/0275 ,  A61B5/145 ,  A61B5/15 ,  A61B5/024 ,  A61B5/20 ,  A61B5/02 ,  A61B5/1455 ,  G16H20/17

CPC classification number: A61B5/157 ,  A61B5/0071 ,  A61B5/0205 ,  A61B5/029 ,  A61B5/02042 ,  A61B5/02416 ,  A61B5/02755 ,  A61B5/1455 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/15003 ,  A61B5/201 ,  A61B5/412 ,  A61B5/441 ,  A61B5/742 ,  G16H20/17

Abstract: Systems and methods are disclosed for providing ongoing monitoring and updating of blood volume status, where the system or method can include guidance in the form of recommendations for treatment actions or alerts about altered patient status.