公开(公告)号：US11878160B2

公开(公告)日：2024-01-23

申请号：US15752502

申请日：2016-08-18

Applicant: GALVANI BIOELECTRONICS LIMITED

Inventor： Michael John Carr ,  Kevin K. Kwong ,  Gerald E. Hunsberger

IPC: A61N1/20 ,  A61N1/36 ,  A61B5/388 ,  A61B5/08 ,  A61B5/087 ,  A61B5/091 ,  A61B5/145 ,  A61B5/00

CPC classification number: A61N1/205 ,  A61B5/087 ,  A61B5/0816 ,  A61B5/091 ,  A61B5/14542 ,  A61B5/388 ,  A61B5/4035 ,  A61B5/4836 ,  A61N1/3611 ,  A61N1/36053 ,  A61N1/36057 ,  A61N1/36171 ,  A61B5/08

Abstract: The present invention provides devices and methods that can prevent or ameliorate bronchoconstriction by stimulating neural activity, in contrast to those techniques based on denervation, ablation or blocking of neural activity. Methods and devices according to the invention may act responsively or on demand, can preserve neuronal structure and function and will be associated with minimal collateral side-effects. In particular, the invention provides devices and methods in which a signal is delivered to the vagus nerve, for example the cervical vagus nerve or the pulmonary branch of the vagus nerve, in order to stimulate neural activity in the vagal nerve.

公开(公告)号：US20240131327A1

公开(公告)日：2024-04-25

申请号：US18537151

申请日：2023-12-12

Applicant: Galvani Bioelectronics Limited

Inventor： Michael John Carr ,  Kevin K. Kwong ,  Gerald E. Hunsberger

IPC: A61N1/20 ,  A61B5/00 ,  A61B5/08 ,  A61B5/087 ,  A61B5/091 ,  A61B5/145 ,  A61B5/388 ,  A61N1/36

CPC classification number: A61N1/205 ,  A61B5/0816 ,  A61B5/087 ,  A61B5/091 ,  A61B5/14542 ,  A61B5/388 ,  A61B5/4035 ,  A61B5/4836 ,  A61N1/36053 ,  A61N1/36057 ,  A61N1/3611 ,  A61N1/36171 ,  A61B5/08

Abstract: The present invention provides devices and methods that can prevent or ameliorate bronchoconstriction by stimulating neural activity, in contrast to those techniques based on denervation, ablation or blocking of neural activity. Methods and devices according to the invention may act responsively or on demand, can preserve neuronal structure and function and will be associated with minimal collateral side-effects. In particular, the invention provides devices and methods in which signals are delivered to the vagus nerve in order to stimulate neural activity in the vagal nerve.