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公开(公告)号：US11992685B2
公开(公告)日：2024-05-28
申请号：US17161086
申请日：2021-01-28
Inventor： Hossein Kassiri Bidhendi , Nima Soltani , Roman Genov
IPC: A61N1/36 , A61B5/00 , A61B5/145 , A61B5/318 , A61B5/369 , A61B5/398 , A61N1/04 , A61N1/05 , A61N1/375 , A61N1/378 , G06N20/00
CPC classification number: A61N1/36135 , A61B5/0031 , A61B5/0042 , A61B5/14532 , A61B5/14546 , A61B5/318 , A61B5/369 , A61B5/398 , A61B5/4094 , A61B5/686 , A61B5/7225 , A61B5/7275 , A61B5/7282 , A61N1/0456 , A61N1/0476 , A61N1/0529 , A61N1/0551 , A61N1/36 , A61N1/36031 , A61N1/36034 , A61N1/36057 , A61N1/36139 , A61N1/3756 , G06N20/00 , A61N1/37514 , A61N1/3787
Abstract: There is provided a neurostimulator and method for delivering to a subject a stimulation in response to a predicted or detected condition. The neurostimulator including: a power circuit for providing electrical power to the neurostimulator; a recording array having a plurality of electrodes for recording a plurality of neurophysiological signals corresponding to a plurality of sites of the subject; a signal processor configured to: determine a phase synchrony among the neurophysiological signals; and associate selected phase synchrony calculations with the prediction or detection of a neurological or neurophysiological condition; and one or more stimulators for delivering to the subject a stimulation in response to the predicted or detected condition.
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公开(公告)号：US11957894B2
公开(公告)日：2024-04-16
申请号：US16947947
申请日：2020-08-25
Applicant: Medtronic, Inc.
Inventor： Anthony M. Chasensky , Bernard Q. Li , Brad C. Tischendorf , Chris J. Paidosh , Christian S. Nielsen , Craig L. Schmidt , David A. Dinsmoor , Duane L. Bourget , Eric H. Bonde , Erik R. Scott , Forrest C M Pape , Gabriela C. Molnar , Gordon O. Munns , Joel A. Anderson , John E. Kast , Joseph J. Viavattine , Markus W. Reiterer , Michael J. Ebert , Phillip C. Falkner , Prabhakar A. Tamirisa , Randy S. Roles , Reginald D. Robinson , Richard T. Stone , Shawn C. Kelley , Stephen J. Roddy , Thomas P. Miltich , Timothy J. Denison , Todd V. Smith , Xuan K. Wei
CPC classification number: A61N1/02 , A61B17/00234 , A61N1/05 , A61N1/0551 , A61N1/36007 , A61N1/3605 , A61N1/36057 , A61N1/36067 , A61N1/36071 , A61N1/36139 , A61N1/37205 , A61N1/37223 , A61N1/37235 , A61N1/37247 , A61N1/3727 , A61N1/3754 , A61N1/3756 , A61N1/3787 , A61N1/36021 , A61N1/36053 , A61N1/37211 , A61N1/37518 , F04C2270/0421
Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.
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公开(公告)号：US11878159B2
公开(公告)日：2024-01-23
申请号：US17327926
申请日：2021-05-24
Applicant: LivaNova USA, Inc.
Inventor： Imad Libbus , Badri Amurthur , Bruce H. Kenknight
CPC classification number: A61N1/0556 , A61N1/36053 , A61N1/36114 , A61N1/36175 , A61N1/36057
Abstract: An implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction is provided. A stimulation therapy lead includes helical electrodes configured to conform to an outer diameter of a cervical vagus nerve sheath, and a set of connector pins electrically connected to the helical electrodes. A neurostimulator includes an electrical receptacle into which the connector pins are securely and electrically coupled. The neurostimulator also includes a pulse generator configured to therapeutically stimulate the vagus nerve through the helical electrodes in alternating cycles of stimuli application and stimuli inhibition that are tuned to both efferently activate the heart's intrinsic nervous system and afferently activate the patient's central reflexes by triggering bi-directional action potentials.
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公开(公告)号：US11864820B2
公开(公告)日：2024-01-09
申请号：US16574843
申请日：2019-09-18
Applicant: CILAG GMBH INTERNATIONAL
Inventor： David C. Yates , Jeffrey D. Messerly , Cameron D. McLain , Peter K. Shires , Frederick L. Estera , Cameron R. Nott , Foster B. Stulen , Christopher A Papa
IPC: A61B18/14 , A61N1/04 , A61B17/32 , A61B17/295 , A61B17/29 , A61B17/285 , A61B17/28 , A61N1/05 , A61N1/36 , A61B17/00 , A61B18/00 , A61B18/12 , A61B18/16
CPC classification number: A61B18/1442 , A61B17/285 , A61B17/2812 , A61B17/29 , A61B17/295 , A61B17/320068 , A61B17/320092 , A61N1/0551 , A61N1/3605 , A61N1/36057 , A61N1/36146 , A61B2017/00017 , A61B2017/2945 , A61B2017/320093 , A61B2017/320094 , A61B2017/320095 , A61B2018/0063 , A61B2018/00083 , A61B2018/00434 , A61B2018/00601 , A61B2018/00607 , A61B2018/00958 , A61B2018/00994 , A61B2018/126 , A61B2018/1253 , A61B2018/162 , A61N1/04
Abstract: Aspects of the present disclosure are presented for a single surgical instrument configured to grasp, seal, and/or cut tissue through application of therapeutic energy, and also detect nerves through application of non-therapeutic electrical energy. A medical device may include two jaws at an end effector, used to apply therapeutic energy and to perform surgical procedures. The therapeutic energy may be in the form of ultrasonic vibrations or higher voltage electrosurgical energy. One of the jaws may be configured to cut tissue through application of the blade. In addition, one or both of the two jaws may be configured to apply nontherapeutic energy for nerve stimulation probing. The application of therapeutic energy may be disabled while the nontherapeutic nerve stimulation energy is applied, and vice versa. The nontherapeutic nerve stimulation energy may be applied to the use of one or more probes positioned near one or both of the jaws.
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公开(公告)号：US20230405339A1
公开(公告)日：2023-12-21
申请号：US18242939
申请日：2023-09-06
Inventor： Douglas Michael Ackermann , Daniel Palanker , James Donald Loudin , Garrett Cale Smith , Victor Wayne McCray , Brandon McNary Felkins
CPC classification number: A61N1/37205 , A61N1/3606 , A61N1/3756 , A61N1/37211 , A61N1/36046 , A61N1/36142 , A61N1/36057 , A61N1/3787
Abstract: A stimulation system stimulates anatomical targets in a patient for treatment of dry eye. The system may include a controller and a microstimulator. The controller may be implemented externally to or internally within the microstimulator. The components of the controller and microstimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and microstimulator may communicate wirelessly or via a wired connection. The microstimulator may generate pulses from a controller signal and apply the signal via one or more electrodes to an anatomical target. The microstimulator may not have any intelligence or logic to shape or modify a signal. The microstimulator may be a passive device configured to generate a pulse based on a signal received from the controller. The microstimulator may shape or modify a signal. Waveforms having different frequency, amplitude and period characteristics may stimulate different anatomical targets in a patient.
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Patent Agency Ranking
公开(公告)号：US20230381520A1
公开(公告)日：2023-11-30
申请号：US18231071
申请日：2023-08-07
Applicant: Medtronic, Inc.
Inventor： Gary W. King , Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Jordan J. Greenberg , Kenneth T. Heruth , Mark S. Lent , Paul W. Wacnik
IPC: A61N1/36
CPC classification number: A61N1/36139 , A61N1/36071 , A61N1/36057
Abstract: Peripheral nerve field stimulation (PNFS) may be controlled based on detected physiological effects of the PNFS, which may be an efferent response to the PNFS. In some examples, a closed-loop therapy system may include a sensing module that senses a physiological parameter of the patient, which may be indicative of the patient's response to the PNFS. Based on a signal generated by the sensing module, the PNFS may be activated, deactivated or modified. Example physiological parameters of the patient include heart rate, respiratory rate, electrodermal activity, muscle activity, blood flow rate, sweat gland activity, pilomotor reflex, or thermal activity of the patient's body. In some examples, a patient pain state may be detected based on a signal generated by the sensing module, and therapy may be controlled based on the detection of the pain state.
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公开(公告)号：US20230347140A1
公开(公告)日：2023-11-02
申请号：US18213964
申请日：2023-06-26
Applicant: Galvani Bioelectronics Limited
Inventor： Matteo Donega , Daniel John Chew , Margarita J. Vervoordeldonk , Isha Gupta
CPC classification number: A61N1/0556 , A61N1/0553 , A61N1/36053 , A61N1/36057 , A61N1/36071 , A61N1/36114 , A61N1/36135 , A61N1/36171 , A61N1/3787
Abstract: Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging and shock.
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公开(公告)号：US11730948B2
公开(公告)日：2023-08-22
申请号：US16947946
申请日：2020-08-25
Applicant: Medtronic, Inc.
Inventor： Brad C. Tischendorf , John E. Kast , Thomas P. Miltich , Gordon O. Munns , Randy S. Roles , Craig L. Schmidt , Joseph J. Viavattine , Christian S. Nielsen , Prabhakar A. Tamirisa , Anthony M. Chasensky , Markus W. Reiterer , Chris J. Paidosh , Reginald D. Robinson , Bernard Q. Li , Erik R. Scott , Phillip C. Falkner , Xuan K. Wei , Eric H. Bonde
CPC classification number: A61N1/02 , A61B17/00234 , A61N1/05 , A61N1/0551 , A61N1/3605 , A61N1/36007 , A61N1/36057 , A61N1/36067 , A61N1/36071 , A61N1/36139 , A61N1/3727 , A61N1/3754 , A61N1/3756 , A61N1/3787 , A61N1/37205 , A61N1/37223 , A61N1/37235 , A61N1/37247 , A61N1/36021 , A61N1/36053 , A61N1/37211 , A61N1/37518 , F04C2270/0421
Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.
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公开(公告)号：US20190239947A1
公开(公告)日：2019-08-08
申请号：US16282613
申请日：2019-02-22
Applicant: Nyxoah SA
Inventor： Adi Mashiach
CPC classification number: A61B18/1492 , A61B2018/00404 , A61B2018/00434 , A61B2018/00577 , A61B2018/1465 , A61N1/0551 , A61N1/36057 , A61N1/36117 , A61N1/36125 , A61N1/37223
Abstract: Systems and methods for hypertension control via energy delivery to one or more nerves affecting blood pressure are provided. Systems may include implantable devices configured for non-contacting neuromodulation. Implantable devices may be configured for intravascular implantation. Systems may also include external devices configured to communicated with implantable neuromodulation devices, Additional systems may include non-implantable devices for delivering modulation energy and ablation energy to one or more nerves affecting blood pressure.
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公开(公告)号：US20190216328A1
公开(公告)日：2019-07-18
申请号：US16331037
申请日：2017-04-17
Applicant: Utku BUYUKSAHIN
Inventor： Utku BUYUKSAHIN
CPC classification number: A61B5/0082 , A61B5/0002 , A61B5/04001 , A61B5/6877 , A61B2562/0209 , A61B2562/0233 , A61B2562/04 , A61B2562/223 , A61N1/0543 , A61N1/0551 , A61N1/36057 , A61N1/36125 , A61N1/36128 , A61N1/37217 , G06F3/015
Abstract: A data transmission system for transmitting an electrical data to a nerve cell. A data receiving system for receiving an electrical data from a nerve cell has at least two phototransistor crystals that is stimulated by light to form an electrical signal; an image source that allows the light to be sent to the phototransistor crystals and allows controlling the amount of light transmitted to each phototransistor crystal independently of each other, and at least one control unit that is connected to the image source that controls the amount of light transmitted from the image source to each of the phototransistor crystals.
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