公开(公告)号：US20210139886A1

公开(公告)日：2021-05-13

申请号：US17134604

申请日：2020-12-28

申请人： Gen-Probe Incorporated

发明人： Kui Gao ,  Jijumon Chelliserry ,  Jeffrey Linnen

IPC分类号： C12N15/10 ,  C12Q1/6806 ,  C12Q1/70

摘要： Disclosed herein are lysis reagents for lysing red blood cells, thereby releasing an analyte, such as RNA from a host or pathogen, in a form suitable for analysis. The reagent includes at least a buffer, a detergent and one or both of a chloride containing salt and an anti-coagulant. The reagent serves to lyse blood cells, protect the released analyte from degradation in the lysate, and is compatible with subsequent steps for analysis of the analyte such as target capture, amplification, detection, or sequencing.

公开(公告)号：US11162091B2

公开(公告)日：2021-11-02

申请号：US16094070

申请日：2017-04-26

申请人： Gen-Probe Incorporated

发明人： Kui Gao ,  Jijumon Chelliserry ,  Jeffrey Linnen

IPC分类号： C12N15/10 ,  C12Q1/6806 ,  C12Q1/70

摘要： Disclosed herein are lysis reagents for lysing red blood cells, thereby releasing an analyte, such as RNA from a host or pathogen, in a form suitable for analysis. The reagent includes at least a buffer, a detergent and one or both of a chloride containing salt and an anti-coagulant. The reagent serves to lyse blood cells, protect the released analyte from degradation in the lysate, and is compatible with subsequent steps for analysis of the analyte such as target capture, amplification, detection, or sequencing.

公开(公告)号：US20220002707A1

公开(公告)日：2022-01-06

申请号：US17485599

申请日：2021-09-27

申请人： Gen-Probe Incorporated

发明人： Kui Gao ,  Jijumon Chelliserry ,  Jeffrey Linnen

IPC分类号： C12N15/10 ,  C12Q1/6806 ,  C12Q1/70

摘要： Disclosed herein are lysis reagents for lysing red blood cells, thereby releasing an analyte, such as RNA from a host or pathogen, in a form suitable for analysis. The reagent includes at least a buffer, a detergent and one or both of a chloride containing salt and an anti-coagulant. The reagent serves to lyse blood cells, protect the released analyte from degradation in the lysate, and is compatible with subsequent steps for analysis of the analyte such as target capture, amplification, detection, or sequencing.

公开(公告)号：US20190136225A1

公开(公告)日：2019-05-09

申请号：US16094070

申请日：2017-04-26

申请人： Gen-Probe Incorporated

发明人： Kui Gao ,  Jijumon Chelliserry ,  Jeffrey Linnen

IPC分类号： C12N15/10 ,  C12Q1/6806 ,  C12Q1/70

摘要： Disclosed herein are lysis reagents for lysing red blood cells, thereby releasing an analyte, such as RNA from a host or pathogen, in a form suitable for analysis. The reagent includes at least a buffer, a detergent and one or both of a chloride containing salt and an anti-coagulant. The reagent serves to lyse blood cells, protect the released analyte from degradation in the lysate, and is compatible with subsequent steps for analysis of the analyte such as target capture, amplification, detection, or sequencing.

公开(公告)号：US12071615B2

公开(公告)日：2024-08-27

申请号：US17485599

申请日：2021-09-27

申请人： Gen-Probe Incorporated

发明人： Kui Gao ,  Jijumon Chelliserry ,  Jeffrey Linnen

IPC分类号： C12N15/10 ,  C12Q1/6806 ,  C12Q1/70

CPC分类号： C12N15/1003 ,  C12Q1/6806 ,  C12Q1/70 ,  Y02A50/30 ,  C12Q1/6806 ,  C12Q2525/161 ,  C12Q2527/125 ,  C12Q2531/143 ,  C12Q2565/501 ,  C12Q1/70 ,  C12Q2525/161 ,  C12Q2527/125 ,  C12Q2531/143 ,  C12Q2565/501

摘要： Disclosed herein are lysis reagents for lysing red blood cells, thereby releasing an analyte, such as RNA from a host or pathogen, in a form suitable for analysis. The reagent includes at least a buffer, a detergent and one or both of a chloride containing salt and an anti-coagulant. The reagent serves to lyse blood cells, protect the released analyte from degradation in the lysate, and is compatible with subsequent steps for analysis of the analyte such as target capture, amplification, detection, or sequencing.

公开(公告)号：US11015185B1

公开(公告)日：2021-05-25

申请号：US17134604

申请日：2020-12-28

申请人： Gen-Probe Incorporated

发明人： Kui Gao ,  Jijumon Chelliserry ,  Jeffrey Linnen

IPC分类号： C12N15/10 ,  C12Q1/6806 ,  C12Q1/70

摘要： Disclosed herein are lysis reagents for lysing red blood cells, thereby releasing an analyte, such as RNA from a host or pathogen, in a form suitable for analysis. The reagent includes at least a buffer, a detergent and one or both of a chloride containing salt and an anti-coagulant. The reagent serves to lyse blood cells, protect the released analyte from degradation in the lysate, and is compatible with subsequent steps for analysis of the analyte such as target capture, amplification, detection, or sequencing.