公开(公告)号：US10739263B2

公开(公告)日：2020-08-11

申请号：US16219388

申请日：2018-12-13

Applicant: GEN-PROBE INCORPORATED

Inventor： David Opalsky ,  Srajan Raghuwanshi ,  James Bui

IPC: G01N21/64 ,  G01N21/03 ,  G01N21/27 ,  G01N21/75 ,  G01N35/02 ,  G01N35/00 ,  G01N35/04

Abstract: A system including an optical signal detector and a controller operatively coupled to the optical signal detector and configured to determine an operational performance status of the optical signal detector. The optical signal detector includes a detection channel having a light source and a sensor, where the detection channel is configured to emit and focus light generated by the light source at a detection zone and to receive and focus light on the sensor. The optical performance status of the optical signal detector is based on a measured characteristic of light focused on the sensor while a non-fluorescent surface is in the detection zone and/or a measured characteristic of light focused on the sensor while a void is in the detection zone.

公开(公告)号：US11726041B2

公开(公告)日：2023-08-15

申请号：US17840388

申请日：2022-06-14

Applicant: GEN-PROBE INCORPORATED

Inventor： David Opalsky ,  Srajan Raghuwanshi ,  James Bui

IPC: G01N21/64 ,  G01N21/03 ,  G01N21/27 ,  G01N21/75 ,  G01N35/02 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N21/645 ,  G01N21/0332 ,  G01N21/276 ,  G01N21/75 ,  G01N35/025 ,  G01N35/00732 ,  G01N2021/6441 ,  G01N2035/00356 ,  G01N2035/0455 ,  G01N2035/0475 ,  G01N2035/0484 ,  G01N2201/0407 ,  G01N2201/0415 ,  G01N2201/12723

Abstract: A method for measuring optical signal detector performance that includes directing light emitted from an optical signal detector onto a first non-fluorescent surface portion in a first detection zone of the optical signal detector. A first characteristic of light detected by a first sensor of the first optical signal detector is measured while the first non-fluorescent surface portion is in the first detection zone of the optical signal detector. Light emitted from the optical signal detector is directed into a first void in the first detection zone of the optical signal detector. A second characteristic of light detected by the first sensor of the optical signal detector is measured while the first void is in the first detection zone of the optical signal detector. And an operational performance status of the optical signal detector is determined based on at least one of the first characteristic and the second characteristic.

公开(公告)号：US10190984B2

公开(公告)日：2019-01-29

申请号：US15389897

申请日：2016-12-23

Applicant: Gen-Probe Incorporated

Inventor： David Opalsky ,  Srajan Raghuwanshi ,  James Bui

IPC: G01N21/75 ,  G01N21/64 ,  G01N21/03 ,  G01N21/27 ,  G01N35/02 ,  G01N35/00 ,  G01N35/04

Abstract: A system for measuring optical signal detector performance includes an optical signal detector comprising a first detection channel having a first light source and a first sensor. The first detection channel is configured to emit and focus light generated by the first light source at a first detection zone, and to receive and focus light on the first sensor. The system also includes a controller operatively coupled to the optical signal detector and configured to determine an operational performance status of the optical signal detector based on at least one of (i) a first measured characteristic of light focused on the sensor while a first non-fluorescent surface portion is in the first detection zone and (ii) a second measured characteristic of light focused on the sensor while a void is in the first detection zone. The optical signal detector can be a fluorometer.