公开(公告)号：US20240132487A1

公开(公告)日：2024-04-25

申请号：US17769198

申请日：2020-10-15

Applicant: Givaudan SA

Inventor： Nicolas COCITO ARMANINO ,  Agnes BOMBRUN ,  An CHAI ,  Julie CHARPENTIER ,  Chun CHEN ,  Roger EMTER ,  Marion MATHYS ,  Andreas NATSCH ,  Chao WANG ,  Lijun ZHOU

IPC: C07D417/14 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14

CPC classification number: C07D417/14 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07B2200/07 ,  C07B2200/09

Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.

公开(公告)号：US20230098332A1

公开(公告)日：2023-03-30

申请号：US17800049

申请日：2021-03-04

Applicant: Givaudan SA

Inventor： Nicolas COCITO ARMANINO ,  Julie CHARPENTIER ,  Chun CHEN ,  Changming DING ,  Roger EMTER ,  Andreas NATSCH ,  Chao WANG ,  Lijun ZHOU

IPC: C07D295/096 ,  C07D309/04 ,  C07D335/02 ,  C07D279/12 ,  C07D241/04

Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucosa.

公开(公告)号：US20240426807A1

公开(公告)日：2024-12-26

申请号：US18570418

申请日：2022-06-21

Applicant: Givaudan SA

Inventor： Roger EMTER ,  Andreas NATSCH

IPC: G01N33/50 ,  C12N9/22 ,  C12N15/11 ,  C12N15/90

Abstract: Described herein are nucleic acid constructs comprising a promoter and/or enhancer sequence operably linked to a nucleic acid sequence encoding a polypeptide, wherein said promoter and/or enhancer is inducible by an olfactory receptor, cells and populations comprising said constructs, and methods for expressing olfactory receptors and for identifying novel olfactory receptors and receptor-ligand interactions.

公开(公告)号：US20230002334A1

公开(公告)日：2023-01-05

申请号：US17777910

申请日：2020-11-26

Applicant: Givaudan SA

Inventor： Chao WANG ,  Nicolas COCITO ARMANINO ,  Julie CHARPENTIER ,  Chun CHEN ,  Roger EMTER ,  Andreas GOEKE ,  Feng HUANG ,  Andreas NATSCH ,  Lijun ZHOU ,  Yue ZOU

IPC: C07D265/16 ,  C07D498/04 ,  A61Q19/00 ,  A61Q11/02

Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.