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1.发明授权Heterocyclic compounds based on N6-substituted adenine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds 有权基于N6取代腺嘌呤的杂环化合物，其制备方法，其用于制备药物，化妆品制剂和生长调节剂，药物制剂，化妆品制剂和含有这些化合物的生长调节剂公开(公告)号：US08552013B2
公开(公告)日：2013-10-08
申请号：US11779828
申请日：2007-07-18
申请人： Igor Popa , Jan Holub , René Lenobel , Stefaan Werbrouck , Karel Dolezal , Miroslav Strnad , Marek Zatloukal , Frank J. Massino
发明人： Igor Popa , Jan Holub , René Lenobel , Stefaan Werbrouck , Karel Dolezal , Miroslav Strnad , Marek Zatloukal , Frank J. Massino
IPC分类号： A01N43/90 , A01N43/48 , A61K8/00 , A61K31/52 , A61K8/49 , A61P43/00 , A61P17/06 , C07D473/34 , C07D473/00 , A61Q19/00 , A61Q19/08
CPC分类号： A01N43/90 , A61K8/4953 , A61Q19/00 , A61Q19/08
摘要： Novel heterocyclic derivatives based on N6-substituted adenine, having anticancer, mitotic, immunosuppressive and antisenescent properties for plant, animal and human cells and methods of their preparation. Included are also pharmaceutical compositions, cosmetic preparations and growth regulators, which contain these derivatives as active compound and the use of these derivatives for the preparation of drugs, cosmetic preparations, in biotechnological processes, in cosmetics and in agriculture.
摘要翻译： 基于N6取代腺嘌呤的新型杂环衍生物，具有植物，动物和人细胞的抗癌，有丝分裂，免疫抑制和抗衰老特性及其制备方法。 还包括药物组合物，化妆品制剂和生长调节剂，其含有这些衍生物作为活性化合物，以及这些衍生物在制备药物，化妆品制剂，生物技术方法，化妆品和农业中的用途。
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2.发明授权Heterocyclic compound based on N6-substituted adenine, methods, of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds 有权基于N6-取代腺嘌呤的杂环化合物，其制备方法，其用于制备药物，化妆品制剂和生长调节剂的用途，药物制剂，化妆品制剂和含有这些化合物的生长调节剂公开(公告)号：US07279482B2
公开(公告)日：2007-10-09
申请号：US10485091
申请日：2002-08-01
申请人： Karel Dolezal , Igor Popa , Jan Holub , René Lenobel , Stefaan Werbrouck , Miroslav Strnad , Marek Zatloukal
发明人： Karel Dolezal , Igor Popa , Jan Holub , René Lenobel , Stefaan Werbrouck , Miroslav Strnad , Marek Zatloukal
IPC分类号： C07D473/34 , A61K31/52 , A61P37/06 , A61P35/00 , A01N43/54
CPC分类号： A01N43/90 , A61K8/4953 , A61Q19/00 , A61Q19/08
摘要： Heterocyclic derivatives based on N6-substituted adenine of, e.g.,a formula: wherein R2 is hydrogen, R6 is R6′-X, X is —NH—, and R6′ is substituted phenyl or substituted benzyl. The derivatives possess anticancer, mitotic, imunosuppressive and antisenescent properties for plant, animal and human cells, and methods of their preparation are disclosed. Included are also pharmaceutical compositions, cosmetic preparations and growth regulators, which contain these derivatives as active compound and the use of these derivatives for the preparation of drugs, cosmetic preparations, in biotechnological processes, in cosmetics and in agriculture.
摘要翻译： 基于N 6 - 取代腺嘌呤的杂环衍生物，例如下式：其中R2是氢，R6是R6'-X，X是-NH-，R6'是取代的苯基或取代的苄基 。 该衍生物具有植物，动物和人类细胞的抗癌，有丝分裂，抑制和抗衰老特性，并且公开了它们的制备方法。 还包括药物组合物，化妆品制剂和生长调节剂，其含有这些衍生物作为活性化合物，以及这些衍生物在制备药物，化妆品制剂，生物技术方法，化妆品和农业中的用途。
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3.发明申请HETEROCYCLIC COMPOUNDS BASED ON N6-SUBSTITUTED ADENINE, METHODS OF THEIR PREPARATION, THEIR USE FOR PREPARATION OF DRUGS, COSMETIC PREPARATIONS AND GROWTH REGULATORS, PHARMACEUTICAL PREPARATIONS, COSMETIC PREPARATIONS AND GROWTH REGULATORS CONTAINING THESE COMPOUNDS 有权基于N6取代腺嘌呤的杂环化合物，其制备方法，其制备药物，化妆品制剂和生长调节剂，药物制剂，化妆品制剂和含有这些化合物的生长调节剂的使用公开(公告)号：US20080014227A1
公开(公告)日：2008-01-17
申请号：US11779828
申请日：2007-07-18
申请人： Igor Popa , Jan Holub , Rene Lenobel , Stefaan Werbrouck , Karel Dolezal , Miroslav Strnad , Marek Zatloukal , Frank Massino
发明人： Igor Popa , Jan Holub , Rene Lenobel , Stefaan Werbrouck , Karel Dolezal , Miroslav Strnad , Marek Zatloukal , Frank Massino
CPC分类号： A01N43/90 , A61K8/4953 , A61Q19/00 , A61Q19/08
摘要： Novel heterocyclic derivatives based on N6-substituted adenine, having anticancer, mitotic, immunosuppressive and antisenescent properties for plant, animal and human cells and methods of their preparation. Included are also pharmaceutical compositions, cosmetic preparations and growth regulators, which contain these derivatives as active compound and the use of these derivatives for the preparation of drugs, cosmetic preparations, in biotechnological processes, in cosmetics and in agriculture.
摘要翻译： 基于N 6 - 取代腺嘌呤的新型杂环衍生物，具有植物，动物和人细胞的抗癌，有丝分裂，免疫抑制和抗衰老特性及其制备方法。 还包括药物组合物，化妆品制剂和生长调节剂，其含有这些衍生物作为活性化合物，以及这些衍生物在制备药物，化妆品制剂，生物技术方法，化妆品和农业中的用途。
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4.发明申请Heterocyclic compound based on n6-substituted adenine, methods, of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds 有权基于n6取代腺嘌呤的杂环化合物，其制备方法，其用于制备药物，化妆品制剂和生长调节剂的用途，药物制剂，化妆品制剂和含有这些化合物的生长调节剂公开(公告)号：US20050043328A1
公开(公告)日：2005-02-24
申请号：US10485091
申请日：2002-08-01
申请人： Karel Dolezal , Igor Popa , Jan Holub , Rene Lenobel , Stefaan Werbrouck , Miroslav Strnad , Marek Zatloukal
发明人： Karel Dolezal , Igor Popa , Jan Holub , Rene Lenobel , Stefaan Werbrouck , Miroslav Strnad , Marek Zatloukal
IPC分类号： C07D473/00 , A01N43/48 , A01N43/90 , A61K8/00 , A61K8/49 , A61K31/52 , A61P3/10 , A61P9/00 , A61P13/12 , A61P17/06 , A61P19/02 , A61P19/06 , A61P25/00 , A61P25/28 , A61P29/00 , A61P33/00 , A61P35/00 , A61P37/06 , A61P43/00 , A61Q19/00 , A61Q19/08 , C07D473/16 , C07D473/34 , C07H19/16 , A61K31/522 , C07D473/10
CPC分类号： A01N43/90 , A61K8/4953 , A61Q19/00 , A61Q19/08
摘要： New heterocyclic derivatives based on N6-substituted adenine, having anticancer, mitotic, imunosuppressive and antisenescent propoerties for plant, animal and human cells and methods of their preparation. Included are also pharmaceutical compositions, cosmetic preparations and growth regulators, which contain these derivatives as active compound and the use of these derivatives for the preparation of drugs, cosmetic preparations, in biotechnological processes, in cosmetics and in agriculture.
摘要翻译： 基于N 6取代腺嘌呤的新型杂环衍生物，具有抗癌，有丝分裂，免疫抑制和抗衰老的植物，动物和人类细胞的优势及其制备方法。 还包括药物组合物，化妆品制剂和生长调节剂，其含有这些衍生物作为活性化合物，以及这些衍生物在制备药物，化妆品制剂，生物技术方法，化妆品和农业中的用途。
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