Tivozanib response prediction
    1.
    发明授权
    Tivozanib response prediction 失效
    Tivozanib反应预测

    公开(公告)号:US07736861B1

    公开(公告)日:2010-06-15

    申请号:US12645355

    申请日:2009-12-22

    IPC分类号: G01N33/53

    摘要: A diagnostic method for predicting whether a human tumor will be sensitive or resistant to treatment with tivozanib (AV-951) is disclosed. The method is based on measurement of macrophage content in a tissue sample from a tumor. Measurement of macrophage content can be based on analysis of macrophage marker gene expression, e.g., by RNA analysis or immunohistochemistry.

    摘要翻译: 公开了一种诊断方法,用于预测人肿瘤是否敏感或对利托那尼治疗有抗药性(AV-951)。 该方法基于来自肿瘤的组织样品中巨噬细胞含量的测量。 巨噬细胞含量的测定可以基于巨噬细胞标记基因表达的分析,例如通过RNA分析或免疫组织化学。

    TIVOZANIB RESPONSE PREDICTION
    2.
    发明申请
    TIVOZANIB RESPONSE PREDICTION 审中-公开
    TIVOZANIB反应预测

    公开(公告)号:US20120231478A1

    公开(公告)日:2012-09-13

    申请号:US13502476

    申请日:2010-06-03

    IPC分类号: G01N33/566

    摘要: A diagnostic method for predicting whether a human tumor will be sensitive or resistant to treatment with tivozanib (AV-951) is disclosed. The method is based on measurement of macrophage content in a tissue sample from a tumor. Measurement of macrophage content can be based on analysis of macrophage marker gene expression, e.g., by RNA analysis or immunohistochemistry.

    摘要翻译: 公开了一种诊断方法,用于预测人肿瘤是否敏感或对利托那尼治疗有抗药性(AV-951)。 该方法基于来自肿瘤的组织样品中巨噬细胞含量的测量。 巨噬细胞含量的测定可以基于巨噬细胞标记基因表达的分析,例如通过RNA分析或免疫组织化学。

    LEAD-FREE FREE-CUTTING CORROSION-RESISTANT SILICON-BISMUTH BRASS ALLOY
    8.
    发明申请
    LEAD-FREE FREE-CUTTING CORROSION-RESISTANT SILICON-BISMUTH BRASS ALLOY 有权
    无铅自由切割耐腐蚀硅 - 双相铜合金

    公开(公告)号:US20120251382A1

    公开(公告)日:2012-10-04

    申请号:US13243754

    申请日:2011-09-23

    IPC分类号: C22C9/04

    CPC分类号: C22C9/00 C22C9/08 C22C9/10

    摘要: A lead-free free-cutting corrosion-resistant silicon-bismuth brass alloy, including the following: between 60.0 and 65.0 wt % of Cu, between 0.6 and 1.8 wt % of Si, between 0.2 and 1.5 wt % of Bi, between 0.02 and 0.5 wt % of Al, less than 1.5 wt % of Ni+Mn+Sn, between 0.01 and 0.5 wt % of La—Ce alloy, between 0.002 and 0.02 wt % of B, with the remainder being Zn and inevitable impurities, wherein the total amount of impurities are no more than 0.5 wt %.

    摘要翻译: 一种无铅自由切削耐腐蚀的铋铋黄铜合金,其包括:Cu的60.0和65.0重量%,Si的0.6-1.8重量%,Bi的0.2和1.5重量%之间,0.02和 0.5重量%的Al,小于1.5重量%的Ni + Mn + Sn,0.01〜0.5重量%的La-Ce合金,0.002〜0.02重量%的B,余量为Zn和不可避免的杂质,其中 杂质总量不超过0.5重量%。

    Lead-free free-cutting corrosion-resistant silicon-bismuth brass alloy
    10.
    发明授权
    Lead-free free-cutting corrosion-resistant silicon-bismuth brass alloy 有权
    无铅切削耐腐蚀硅铋黄铜合金

    公开(公告)号:US08366841B2

    公开(公告)日:2013-02-05

    申请号:US13243754

    申请日:2011-09-23

    IPC分类号: C22C9/04

    CPC分类号: C22C9/00 C22C9/08 C22C9/10

    摘要: A lead-free free-cutting corrosion-resistant silicon-bismuth brass alloy, including the following: between 60.0 and 65.0 wt % of Cu, between 0.6 and 1.8 wt % of Si, between 0.2 and 1.5 wt % of Bi, between 0.02 and 0.5 wt % of Al, less than 1.5 wt % of Ni+Mn+Sn, between 0.01 and 0.5 wt % of La—Ce alloy, between 0.002 and 0.02 wt % of B, with the remainder being Zn and inevitable impurities, wherein the total amount of impurities are no more than 0.5 wt %.

    摘要翻译: 一种无铅自由切削耐腐蚀的铋铋黄铜合金,其包括:Cu的60.0和65.0重量%,Si的0.6-1.8重量%,Bi的0.2和1.5重量%之间,0.02和 0.5重量%的Al,小于1.5重量%的Ni + Mn + Sn,0.01〜0.5重量%的La-Ce合金,0.002〜0.02重量%的B,余量为Zn和不可避免的杂质,其中 杂质总量不超过0.5重量%。