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公开(公告)号:US07960515B2
公开(公告)日:2011-06-14
申请号:US12332944
申请日:2008-12-11
申请人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
发明人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
IPC分类号: C07K16/00 , A61K39/395
CPC分类号: C07K16/2878 , A61K2039/505 , C07K2317/14 , C07K2317/21 , C07K2317/565 , C07K2317/92
摘要: The present disclosure provides isolated binding molecules that bind to the human OX40R, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.
摘要翻译: 本公开提供了结合人OX40R的分离的结合分子,编码结合分子的氨基酸序列的核酸分子,包含核酸分子的载体,含有载体的宿主细胞,制备结合分子的方法,含有 结合分子,以及使用结合分子或组合物的方法。
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公开(公告)号:US20120225086A1
公开(公告)日:2012-09-06
申请号:US13474466
申请日:2012-05-17
申请人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
发明人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
IPC分类号: A61K39/395 , C12N15/63 , C12N5/10 , A61P37/04 , C12N1/19 , C12N5/09 , A61P35/00 , C12N15/13 , C12N1/21
CPC分类号: C07K16/2878 , A61K2039/505 , C07K2317/14 , C07K2317/21 , C07K2317/565 , C07K2317/92
摘要: The present disclosure provides isolated binding molecules that bind to the human OX40R, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.
摘要翻译: 本公开提供了结合人OX40R的分离的结合分子,编码结合分子的氨基酸序列的核酸分子,包含核酸分子的载体,含有载体的宿主细胞,制备结合分子的方法,含有 结合分子,以及使用结合分子或组合物的方法。
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公开(公告)号:US20090214560A1
公开(公告)日:2009-08-27
申请号:US12332944
申请日:2008-12-11
申请人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
发明人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
IPC分类号: A61K39/395 , C07K16/18 , C12N15/11 , C12N15/00 , C12N5/06
CPC分类号: C07K16/2878 , A61K2039/505 , C07K2317/14 , C07K2317/21 , C07K2317/565 , C07K2317/92
摘要: The present disclosure provides isolated binding molecules that bind to the human OX40R, nucleic acid molecules encoding an amino acid sequence of the binding molecules vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.
摘要翻译: 本公开提供了结合人OX40R的分离的结合分子,编码结合分子的氨基酸序列的核酸分子,包含核酸分子的载体,含有载体的宿主细胞,制备结合分子的方法,含有 结合分子,以及使用结合分子或组合物的方法。
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公开(公告)号:US09028824B2
公开(公告)日:2015-05-12
申请号:US13474466
申请日:2012-05-17
申请人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
发明人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
IPC分类号: A61K39/395 , C07K16/28 , A61K39/00
CPC分类号: C07K16/2878 , A61K2039/505 , C07K2317/14 , C07K2317/21 , C07K2317/565 , C07K2317/92
摘要: The present disclosure provides isolated binding molecules that bind to the human OX40R, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.
摘要翻译: 本公开提供了结合人OX40R的分离的结合分子,编码结合分子的氨基酸序列的核酸分子,包含核酸分子的载体,含有载体的宿主细胞,制备结合分子的方法,含有 结合分子,以及使用结合分子或组合物的方法。
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公开(公告)号:US08236930B2
公开(公告)日:2012-08-07
申请号:US13099196
申请日:2011-05-02
申请人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
发明人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
IPC分类号: C07K16/00
CPC分类号: C07K16/2878 , A61K2039/505 , C07K2317/14 , C07K2317/21 , C07K2317/565 , C07K2317/92
摘要: The present disclosure provides isolated binding molecules that bind to the human OX40R, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.
摘要翻译: 本公开提供了结合人OX40R的分离的结合分子,编码结合分子的氨基酸序列的核酸分子,包含核酸分子的载体,含有载体的宿主细胞,制备结合分子的方法,含有 结合分子,以及使用结合分子或组合物的方法。
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公开(公告)号:US20110206681A1
公开(公告)日:2011-08-25
申请号:US13099196
申请日:2011-05-02
申请人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
发明人: Jing Min , Yanli Wu , Rory F. Finn , Barrett R. Thiele , Wei Liao , Ronald P. Gladue , Arvind Rajpal , Timothy J. Paradis , Peter Brams , Brigitte Devaux , Yi Wu , Kristopher Toy , Heidi N. LeBlanc , Haichun Huang
CPC分类号: C07K16/2878 , A61K2039/505 , C07K2317/14 , C07K2317/21 , C07K2317/565 , C07K2317/92
摘要: The present disclosure provides isolated binding molecules that bind to the human OX40R, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.
摘要翻译: 本公开提供了结合人OX40R的分离的结合分子,编码结合分子的氨基酸序列的核酸分子,包含核酸分子的载体,含有载体的宿主细胞,制备结合分子的方法,含有 结合分子,以及使用结合分子或组合物的方法。
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