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公开(公告)号：US20100255576A1
公开(公告)日：2010-10-07
申请号：US12753573
申请日：2010-04-02
IPC分类号： C12N5/20
CPC分类号： C12M23/08 , C12M23/24 , C12M25/06 , C12M25/14 , C12N5/00 , C12N5/0602 , C12N2500/02
摘要： Gas permeable devices and methods are disclosed for cell culture, including cell culture devices and methods that contain medium at heights, and certain gas permeable surface area to medium volume ratios. These devices and methods allow improvements in cell culture efficiency and scale up efficiency.
摘要翻译： 公开了用于细胞培养的透气装置和方法，包括细胞培养装置和在高度含有培养基的方法以及某些气体可渗透的表面积与中等体积比。 这些装置和方法允许提高细胞培养效率并提高效率。
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2.发明申请COMPARTMENTALIZED DEVICE FOR CELL CULTURE, CELL PROCESSING AND SAMPLE DIALYSIS 有权用于细胞培养，细胞处理和样品透析的分层装置公开(公告)号：US20110212519A1
公开(公告)日：2011-09-01
申请号：US12715191
申请日：2010-03-01
IPC分类号： C12N5/07
摘要： A versatile compartmentalized cell culture device, with a selectively permeable membrane separating the compartments, provides many attributes relative to traditional devices. It can be configured for high-density cell culture, co-culture, and sample dialysis while rolling or standing still. It can also be configured for continuous movement of liquid between compartments. The wide combination of attributes not found in other membrane based cell culture and bioprocessing devices includes more cell capacity, more cell secreted product capacity, higher cell and product density, increased medium capacity, minimized use of exogenous growth factors, compatibility with standard cell culture equipment and protocols, increased scale up efficiency, capacity to function when rolling or standing still, capacity for perfusion without the need for pumps, and more efficient sample dialysis.
摘要翻译： 具有分离隔室的选择性渗透膜的多功能隔室细胞培养装置相对于传统装置提供许多属性。 它可以配置为在滚动或静置时进行高密度细胞培养，共培养和样品透析。 它也可以配置为在隔室之间连续移动液体。 在其他基于膜的细胞培养和生物处理装置中没有发现的属性的广泛组合包括更多的细胞容量，更多的细胞分泌产物能力，更高的细胞和产物密度，增加的培养基能力，最小化外源生长因子的使用，与标准细胞培养设备的相容性 和方案，增加放大效率，滚动或静止时功能的能力，无需泵的灌注能力，以及更有效的样品透析。
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公开(公告)号：US08697443B2
公开(公告)日：2014-04-15
申请号：US12753573
申请日：2010-04-02
CPC分类号： C12M23/08 , C12M23/24 , C12M25/06 , C12M25/14 , C12N5/00 , C12N5/0602 , C12N2500/02
摘要： Gas permeable devices and methods are disclosed for cell culture, including cell culture devices and methods that contain medium at heights, and certain gas permeable surface area to medium volume ratios. These devices and methods allow improvements in cell culture efficiency and scale up efficiency.
摘要翻译： 公开了用于细胞培养的透气装置和方法，包括细胞培养装置和在高度含有培养基的方法以及某些气体可渗透的表面积与中等体积比。 这些装置和方法允许提高细胞培养效率并提高效率。
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公开(公告)号：US08501468B2
公开(公告)日：2013-08-06
申请号：US12715191
申请日：2010-03-01
IPC分类号： C12N5/00
摘要： A versatile compartmentalized cell culture device, with a selectively permeable membrane separating the compartments, provides many attributes relative to traditional devices. It can be configured for high-density cell culture, co-culture, and sample dialysis while rolling or standing still. It can also be configured for continuous movement of liquid between compartments. The wide combination of attributes not found in other membrane based cell culture and bioprocessing devices includes more cell capacity, more cell secreted product capacity, higher cell and product density, increased medium capacity, minimized use of exogenous growth factors, compatibility with standard cell culture equipment and protocols, increased scale up efficiency, capacity to function when rolling or standing still, capacity for perfusion without the need for pumps, and more efficient sample dialysis.
摘要翻译： 具有分离隔室的选择性渗透膜的多功能隔室细胞培养装置相对于传统装置提供许多属性。 它可以配置为在滚动或静置时进行高密度细胞培养，共培养和样品透析。 它也可以配置为在隔室之间连续移动液体。 在其他基于膜的细胞培养和生物处理装置中没有发现的属性的广泛组合包括更多的细胞容量，更多的细胞分泌产物能力，更高的细胞和产物密度，增加的培养基能力，最小化外源生长因子的使用，与标准细胞培养设备的相容性 和方案，增加放大效率，滚动或静止时功能的能力，无需泵的灌注能力，以及更有效的样品透析。
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5.发明授权Compartmentalized device for cell culture, cell processing, and sample dialysis 有权用于细胞培养，细胞处理和样品透析的分隔装置公开(公告)号：US07799560B2
公开(公告)日：2010-09-21
申请号：US10985339
申请日：2004-11-10
摘要： A versatile compartmentalized cell culture device, with a selectively permeable membrane separating the compartments, provides many attributes relative to traditional devices. It can be configured for high-density cell culture, co-culture, and sample dialysis while rolling or standing still. It can also be configured for continuous movement of liquid between compartments. The wide combination of attributes not found in other membrane based cell culture and bioprocessing devices includes more cell capacity, more cell secreted product capacity, higher cell and product density, increased medium capacity, minimized use of exogenous growth factors, compatibility with standard cell culture equipment and protocols, increased scale up efficiency, capacity to function when rolling or standing still, capacity for perfusion without the need for pumps, and more efficient sample dialysis.
摘要翻译： 具有分离隔室的选择性渗透膜的多功能隔室细胞培养装置相对于传统装置提供许多属性。 它可以配置为在滚动或静置时进行高密度细胞培养，共培养和样品透析。 它也可以配置为在隔室之间连续移动液体。 在其他基于膜的细胞培养和生物处理装置中没有发现的属性的广泛组合包括更多的细胞容量，更多的细胞分泌产物能力，更高的细胞和产物密度，增加的培养基能力，最小化外源生长因子的使用，与标准细胞培养设备的相容性 和方案，增加放大效率，滚动或静止时功能的能力，无需泵的灌注能力，以及更有效的样品透析。
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公开(公告)号：US20090272748A1
公开(公告)日：2009-11-05
申请号：US12115353
申请日：2008-05-05
CPC分类号： A01N1/0273 , C12M23/08 , C12M23/38 , C12M41/44
摘要： This invention relates to methods and devices that improve the process of culturing cells and/or shipping cells from one location to another. They have the capacity to reduce the risk of contamination, regulate pressure in the medium surrounding cells, and maintain cells in a uniform distribution throughout transit. This leads to an improved level of process control relative to current methods.
摘要翻译： 本发明涉及改善从一个位置到另一个位置培养细胞和/或运送细胞的过程的方法和装置。 他们有能力降低污染风险，调节周围细胞的压力，并保持细胞在整个运输过程中均匀分布。 这导致相对于当前方法的改进的过程控制水平。
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公开(公告)号：US08999703B2
公开(公告)日：2015-04-07
申请号：US12115353
申请日：2008-05-05
申请人： Daniel P. Welch , John R. Wilson
发明人： Daniel P. Welch , John R. Wilson
CPC分类号： A01N1/0273 , C12M23/08 , C12M23/38 , C12M41/44
摘要： This invention relates to methods and devices that improve the process of culturing cells and/or shipping cells from one location to another. They have the capacity to reduce the risk of contamination, regulate pressure in the medium surrounding cells, and maintain cells in a uniform distribution throughout transit. This leads to an improved level of process control relative to current methods.
摘要翻译： 本发明涉及改善从一个位置到另一个位置培养细胞和/或运送细胞的过程的方法和装置。 他们有能力降低污染风险，调节周围细胞的压力，并保持细胞在整个运输过程中均匀分布。 这导致相对于当前方法的改进的过程控制水平。
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公开(公告)号：US20110008877A1
公开(公告)日：2011-01-13
申请号：US12817978
申请日：2010-06-17
申请人： Debra Skelnik , Roger Wilson , Daniel P. Welch , John R. Wilson
发明人： Debra Skelnik , Roger Wilson , Daniel P. Welch , John R. Wilson
IPC分类号： A01N1/02
CPC分类号： A01N1/0273 , A01N1/0263 , A61F2/0095 , A61F2/142
摘要： An apparatus for shipping, storing, and viewing a cornea. The device offers an improvement to cornea health relative to conventional cornea containers.
摘要翻译： 用于运输，存储和观察角膜的装置。 与常规的角膜容器相比，该装置改善角膜健康。
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公开(公告)号：US5454798A
公开(公告)日：1995-10-03
申请号：US61901
申请日：1993-05-14
CPC分类号： A61M25/013 , A61F5/44 , A61M25/002 , A61M25/0111 , A61M2025/0062
摘要： A disposable urine bag having sealed cavity members where one cavity stores an extendable catheter and also acts as a urine storage reservoir. A second sealed and peel-away cavity includes a catheter advancement mechanism which provides for lubricated catheter advancement without actual contact of the catheter by the human hand. An absorption member is provided to semi-solidify urine stored in the urine storage reservoir.
摘要翻译： 具有密封空腔构件的一次性尿袋，其中一个空腔存储可延伸导管并且还用作尿储存容器。 第二密封和剥离空腔包括导管前进机构，其提供润滑的导管前进而没有人手实际接触导管。 提供一种吸收构件以半固化存储在尿液储存容器中的尿液。
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公开(公告)号：USD559748S1
公开(公告)日：2008-01-15
申请号：US29273217
申请日：2007-02-28
申请人： Daniel P. Welch
设计人： Daniel P. Welch
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