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公开(公告)号：US07770467B1
公开(公告)日：2010-08-10
申请号：US12245588
申请日：2008-10-03
IPC分类号： G01N3/02
CPC分类号： G01N3/04 , G01N2203/0017 , G01N2203/0089 , G01N2203/0222 , G01N2203/0274 , G01N2203/0435
摘要： A test fixture for use with a Dynamic Mechanical Analyzer (DMA) restrains a hollow cylindrical tube for purposes of performing either a tensile or transverse/bending load test. The fixture includes a clamp that is configured to restrain the tube without imparting a preload or changing a mechanical property of the tube.
摘要翻译： 用于动态机械分析仪（DMA）的测试夹具限制了空心圆柱形管，用于进行拉伸或横向/弯曲载荷试验。 夹具包括夹持器，其被构造成约束管而不赋予管的预加载力或改变管的机械性能。
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公开(公告)号：US08006568B2
公开(公告)日：2011-08-30
申请号：US12819117
申请日：2010-06-18
IPC分类号： G01D21/00
CPC分类号： G01N3/04 , G01N2203/0017 , G01N2203/0089 , G01N2203/0222 , G01N2203/0274 , G01N2203/0435
摘要： A test fixture for use with a Dynamic Mechanical Analyzer (DMA) restrains a hollow cylindrical tube for purposes of performing either a tensile or transverse/bending load test. The fixture includes a clamp that is configured to restrain the tube without imparting a preload or changing a mechanical property of the tube.
摘要翻译： 用于动态机械分析仪（DMA）的测试夹具限制了空心圆柱形管，用于进行拉伸或横向/弯曲载荷试验。 夹具包括夹持器，其被构造成约束管而不赋予管的预加载力或改变管的机械性能。
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公开(公告)号：US20100251838A1
公开(公告)日：2010-10-07
申请号：US12819117
申请日：2010-06-18
CPC分类号： G01N3/04 , G01N2203/0017 , G01N2203/0089 , G01N2203/0222 , G01N2203/0274 , G01N2203/0435
摘要： A test fixture for use with a Dynamic Mechanical Analyzer (DMA) restrains a hollow cylindrical tube for purposes of performing either a tensile or transverse/bending load test. The fixture includes a clamp that is configured to restrain the tube without imparting a preload or changing a mechanical property of the tube.
摘要翻译： 用于动态机械分析仪（DMA）的测试夹具限制了空心圆柱形管，用于进行拉伸或横向/弯曲载荷试验。 夹具包括夹持器，其被构造成约束管而不赋予管的预加载或改变管的机械性能。
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公开(公告)号：US09199408B2
公开(公告)日：2015-12-01
申请号：US13438211
申请日：2012-04-03
申请人： Yunbing Wang , Rommel Lumauig , James Oberhauser
发明人： Yunbing Wang , Rommel Lumauig , James Oberhauser
CPC分类号： A61F2/958 , A61F2/915 , A61F2002/9522 , B23P11/005 , B23P11/025 , B29C53/02 , B29C2793/0009 , B29K2067/046 , B29K2995/006 , B29L2031/7534 , Y10T29/49865 , Y10T29/49913
摘要： A medical device-includes a scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes one or more balloon pressurization steps. The balloon pressurization steps are selected to enhance scaffold retention to the balloon and maintain a relatively uniform arrangement of balloon folds about the inner surface of the crimped scaffold so that the scaffold expands in a uniform manner when the balloon is inflated.
摘要翻译： 一种医疗装置 - 包括卷曲到具有膨胀气囊的导管的支架。 支架通过包括一个或多个气囊加压步骤的过程卷曲到气囊。 选择球囊加压步骤以增强对球囊的支架保持性，并且保持围绕卷曲的支架的内表面的气球折叠的相对均匀的布置，使得当气囊膨胀时，支架以均匀的方式膨胀。
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5.发明授权Method to minimize molecular weight drop of poly(L-lactide) stent during processing 有权减少加工过程中聚（L-丙交酯）支架分子量下降的方法公开(公告)号：US08207240B2
公开(公告)日：2012-06-26
申请号：US12559402
申请日：2009-09-14
申请人： Byron Lambert , Yunbing Wang , James Oberhauser
发明人： Byron Lambert , Yunbing Wang , James Oberhauser
CPC分类号： B29C47/0076 , A61F2/82 , A61L31/041 , A61L31/06 , A61L31/143 , A61L31/148 , B29D23/20 , B29K2005/00 , B29L2023/20 , B29L2031/753 , C08J3/28 , C08J2367/04 , C08L67/04
摘要： A method to reduce or minimize the reduction in molecular weight of a stent during processing is disclosed. The stent has a scaffolding including a polymer formulation comprising PLLA and polymandelide. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
摘要翻译： 公开了减少或最小化处理期间支架分子量降低的方法。 支架具有包括PLLA和聚扁桃酸酯的聚合物制剂的脚手架。 聚对苯二甲酸丁二醇酯降低加工过程中的分子量下降，特别是在灭菌过程中。 支架支架还可包括一种或多种附加的稳定剂，其另外降低加工过程中的分子量下降。
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公开(公告)号：US20130261729A1
公开(公告)日：2013-10-03
申请号：US13436527
申请日：2012-03-30
申请人： Matthew Gillick , Yunbing Wang , Justin Mann , Bruce Wilson , James Oberhauser
发明人： Matthew Gillick , Yunbing Wang , Justin Mann , Bruce Wilson , James Oberhauser
IPC分类号： A61F2/84
CPC分类号： A61F2/958 , A61F2250/0013 , A61M25/10181 , A61M25/10185
摘要： An apparatus and method for controlling inflation pressure and pressurization rate of a balloon during deployment of a stent or scaffold is disclosed.
摘要翻译： 公开了一种用于在展开支架或支架期间控制气囊的充气压力和加压速率的装置和方法。
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7.发明授权Stents including poly(L-lactide) formulations that minimize molecular weight drop during processing 有权支架，包括聚（L-丙交酯）制剂，使加工过程中的分子量下降最小化公开(公告)号：US08529617B2
公开(公告)日：2013-09-10
申请号：US13481523
申请日：2012-05-25
申请人： Byron Lambert , Yunbing Wang , James Oberhauser
发明人： Byron Lambert , Yunbing Wang , James Oberhauser
IPC分类号： A61F2/06
CPC分类号： B29C47/0076 , A61F2/82 , A61L31/041 , A61L31/06 , A61L31/143 , A61L31/148 , B29D23/20 , B29K2005/00 , B29L2023/20 , B29L2031/753 , C08J3/28 , C08J2367/04 , C08L67/04
摘要： A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
摘要翻译： 公开了一种包括含有PLLA和聚扁桃酸酯的聚合物制剂的支架支架。 聚对苯二甲酸丁二醇酯降低加工过程中的分子量下降，特别是在灭菌过程中。 支架支架还可包括一种或多种附加的稳定剂，其另外降低加工过程中的分子量下降。
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8.发明申请STENTS INCLUDING POLY(L-LACTIDE) FORMULATIONS THAT MINIMIZE MOLECULAR WEIGHT DROP DURING PROCESSING 有权包括在加工过程中最小化分子量降低的聚（L-柠檬酸）配方的方法公开(公告)号：US20120239135A1
公开(公告)日：2012-09-20
申请号：US13481523
申请日：2012-05-25
申请人： Byron Lambert , Yunbing Wang , James Oberhauser
发明人： Byron Lambert , Yunbing Wang , James Oberhauser
CPC分类号： B29C47/0076 , A61F2/82 , A61L31/041 , A61L31/06 , A61L31/143 , A61L31/148 , B29D23/20 , B29K2005/00 , B29L2023/20 , B29L2031/753 , C08J3/28 , C08J2367/04 , C08L67/04
摘要： A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
摘要翻译： 公开了一种包括含有PLLA和聚扁桃酸酯的聚合物制剂的支架支架。 聚对苯二甲酸丁二醇酯降低加工过程中的分子量下降，特别是在灭菌过程中。 支架支架还可包括一种或多种附加的稳定剂，其另外降低加工过程中的分子量下降。
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9.发明申请Method To Minimize Molecular Weight Drop Of Poly(L-Lactide) Stent During Processing 有权减少加工过程中聚（L-丙交酯）支架分子量下降的方法公开(公告)号：US20110065825A1
公开(公告)日：2011-03-17
申请号：US12559402
申请日：2009-09-14
申请人： Byron Lambert , Yunbing Wang , James Oberhauser
发明人： Byron Lambert , Yunbing Wang , James Oberhauser
IPC分类号： C08J3/28
CPC分类号： B29C47/0076 , A61F2/82 , A61L31/041 , A61L31/06 , A61L31/143 , A61L31/148 , B29D23/20 , B29K2005/00 , B29L2023/20 , B29L2031/753 , C08J3/28 , C08J2367/04 , C08L67/04
摘要： A method to reduce or minimize the reduction in molecular weight of a stent during processing is disclosed. The stent has a scaffolding including a polymer formulation comprising PLLA and polymandelide. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
摘要翻译： 公开了减少或最小化处理期间支架分子量降低的方法。 支架具有包括PLLA和聚扁桃酸酯的聚合物制剂的脚手架。 聚对苯二甲酸丁二醇酯降低加工过程中的分子量下降，特别是在灭菌过程中。 支架支架还可包括一种或多种附加的稳定剂，其另外降低加工过程中的分子量下降。
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公开(公告)号：US20110022155A1
公开(公告)日：2011-01-27
申请号：US12506973
申请日：2009-07-21
申请人： Yunbing Wang , James Oberhauser , Xiao Ma
发明人： Yunbing Wang , James Oberhauser , Xiao Ma
IPC分类号： A61F2/06
CPC分类号： A61L31/148 , A61F2/82 , A61L31/06 , B23K26/402 , B23K2103/42 , B23K2103/50 , C08L67/04
摘要： A biodegradable polymeric stent made from poly(L-lactide) and a low concentration of L-lactide monomer is disclosed. The concentration of L-lactide is adjusted to provide a degradation behavior that is suitable for different treatment applications including coronary, peripheral, and nasal.
摘要翻译： 公开了由聚（L-丙交酯）和低浓度的L-丙交酯单体制成的可生物降解的聚合物支架。 调节L-丙交酯的浓度以提供适合于包括冠状动脉，外周和鼻部在内的不同治疗应用的降解行为。
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