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公开(公告)号:US20100261780A1
公开(公告)日:2010-10-14
申请号:US12751572
申请日:2010-03-31
申请人: Jun GAO , Carlos Fleet , Eric Hsu , Anthony Cheung
发明人: Jun GAO , Carlos Fleet , Eric Hsu , Anthony Cheung
IPC分类号: A61K31/7052 , C08B37/08 , C12N15/85 , A61P29/00 , A61P11/00
CPC分类号: C12N15/87 , A61K47/61 , A61K48/0041
摘要: The invention provides highly acidic chitosan-nucleic acid polyplex compositions. The compositions may be used to transfect cells in vitro and in vivo, and are particularly useful for transfecting cells of mucosal epithelia.
摘要翻译: 本发明提供了高度酸性的壳聚糖 - 核酸复合物组合物。 组合物可用于体外和体内转染细胞,并且特别可用于转染粘膜上皮细胞。