公开(公告)号：US20190300843A1

公开(公告)日：2019-10-03

申请号：US16346201

申请日：2017-10-25

Applicant: Kimberly-Clark Worldwide, Inc.

Inventor： Rebecca A. Vongsa ,  David W. Koenig

IPC: C12N1/20 ,  A61K35/741 ,  C12N1/04 ,  C12N1/36 ,  A23L33/135

Abstract: Methods for archiving and reconstituting a microbiome are disclosed. A method for archiving a microbiome can include collecting a sample including a microbial community defining the microbiome. The method can also include expanding the microbial community in the sample and preserving the sample to provide a preserved sample. Packaging the preserved sample to archive the microbiome can also form part of the method of archiving the microbiome.

公开(公告)号：US20240307428A1

公开(公告)日：2024-09-19

申请号：US18673865

申请日：2024-05-24

Applicant: KIMBERLY-CLARK WORLDWIDE, INC.

Inventor： Jingru Li ,  Lindsay A. Peed ,  Paige N. Hollmaier ,  Rebecca A. Vongsa ,  David W. Koenig ,  Cheryce F. Joyner

IPC: A61K31/7068 ,  A61K31/198 ,  A61K45/06

CPC classification number: A61K31/7068 ,  A61K31/198 ,  A61K45/06

Abstract: The present invention relates to compositions, particularly compositions useful in maintaining and supporting healthy microflora in the female urogenital tract which could lead to inhibition of vaginal infections, as well as methods of treating and preventing vaginal infections. Compositions useful in supporting healthy microflora, disclosed herein, generally include a first therapeutic agent including α methyl-D glucoside and a second therapeutic agent including a nitrogen containing compound at a therapeutic amount. In some embodiments, the nitrogen containing compound can be, for example, L-Cysteine, Cytidine, D-Asparagine, Pyrimidine, D-Alanine, D-Glucosamine HCL, and N-Acetyl-D-Glucosamine.

公开(公告)号：US12029748B2

公开(公告)日：2024-07-09

申请号：US16486220

申请日：2017-02-28

Applicant: KIMBERLY-CLARK WORLDWIDE, INC.

Inventor： Jingru Li ,  Lindsay A. Peed ,  Paige N. Hollmaier ,  Rebecca A. Vongsa ,  David W. Koenig ,  Cheryce F. Joyner

IPC: A61K31/7068 ,  A61K31/198 ,  A61K45/06

CPC classification number: A61K31/7068 ,  A61K31/198 ,  A61K45/06

Abstract: The present invention relates to compositions, particularly compositions useful in maintaining and supporting healthy microflora in the female urogenital tract which could lead to inhibition of vaginal infections, as well as methods of treating and preventing vaginal infections. Compositions useful in supporting healthy microflora, disclosed herein, generally include a first therapeutic agent including α methyl-D glucoside and a second therapeutic agent including a nitrogen containing compound at a therapeutic amount. In some embodiments, the nitrogen containing compound can be, for example, L-Cysteine, Cytidine, D-Asparagine, Pyrimidine, D-Alanine, D-Glucosamine HCL, and N-Acetyl-D-Glucosamine.

公开(公告)号：US20200009174A1

公开(公告)日：2020-01-09

申请号：US16486220

申请日：2017-02-28

Applicant: KIMBERLY-CLARK WORLDWIDE, INC.

Inventor： Jingru Li ,  Lindsay A. Peed ,  Paige N. Hollmaier ,  Rebecca A. Vongsa ,  David W. Koenig ,  Cheryce F. Joyner

IPC: A61K31/7068 ,  A61K31/198

Abstract: The present invention relates to compositions, particularly compositions useful in maintaining and supporting healthy microflora in the female urogenital tract which could lead to inhibition of vaginal infections, as well as methods of treating and preventing vaginal infections. Compositions useful in supporting healthy microflora, disclosed herein, generally include a first therapeutic agent including α methyl-D glucoside and a second therapeutic agent including a nitrogen containing compound at a therapeutic amount. In some embodiments, the nitrogen containing compound can be, for example, L-Cysteine, Cytidine, D-Asparagine, Pyrimidine, D-Alanine, D-Glucosamine HCL, and N-Acetyl-D-Glucosamine.