Apparatus and method for generating wave functional pulsatile microflows by applying Fourier cosine series and hydraulic head difference
    2.
    发明授权
    Apparatus and method for generating wave functional pulsatile microflows by applying Fourier cosine series and hydraulic head difference 有权
    通过应用傅里叶余弦系列和液压头差产生波功能脉冲微流的装置和方法

    公开(公告)号:US09291172B2

    公开(公告)日:2016-03-22

    申请号:US14090781

    申请日:2013-11-26

    CPC classification number: F04F7/00 F04D11/00 Y10T137/0318 Y10T137/85978

    Abstract: An apparatus for generating pulsatile flows includes a liquid vessel capable of containing a liquid, a plurality of revolving mechanisms associated with each other, and a microchannel supplied with a liquid from the liquid vessel. As the plurality of revolving mechanisms rotate, a periodically changing pressure difference occurs between the liquid vessel and the microchannel, thereby implementing a pulsatile flow having a wave functional form in the microchannel. By applying the hydraulic head difference and controlling revolution of the revolving mechanisms based on Fourier cosine series, a minute and precise pulsatile flow of a wave functional form may be implemented by means of simple configuration and fabrication, which may not easily obtained by a conventional pump.

    Abstract translation: 用于产生脉冲流的装置包括能够容纳液体的液体容器,与其相关联的多个旋转机构和从液体容器供应液体的微通道。 当多个旋转机构旋转时,在液体容器和微通道之间出现周期性变化的压差,从而在微通道中实现具有波函数形式的脉动流。 通过应用基于傅立叶余弦系列的旋转机构的液压头差和控制旋转,可以通过简单的构造和制造实现波函数形式的微小和精确的脉动流,这可能不容易由常规泵 。

    APPARATUS AND METHOD FOR GENERATING WAVE FUNCTIONAL PULSATILE MICROFLOWS BY APPLYING FOURIER COSINE SERIES AND HYDRAULIC HEAD DIFFERENCE
    3.
    发明申请
    APPARATUS AND METHOD FOR GENERATING WAVE FUNCTIONAL PULSATILE MICROFLOWS BY APPLYING FOURIER COSINE SERIES AND HYDRAULIC HEAD DIFFERENCE 有权
    通过应用FOURIER COSINE系列和液压头差异来产生波功能微量流量的装置和方法

    公开(公告)号:US20140144513A1

    公开(公告)日:2014-05-29

    申请号:US14090781

    申请日:2013-11-26

    CPC classification number: F04F7/00 F04D11/00 Y10T137/0318 Y10T137/85978

    Abstract: An apparatus for generating pulsatile flows includes a liquid vessel capable of containing a liquid, a plurality of revolving mechanisms associated with each other, and a microchannel supplied with a liquid from the liquid vessel. As the plurality of revolving mechanisms rotate, a periodically changing pressure difference occurs between the liquid vessel and the microchannel, thereby implementing a pulsatile flow having a wave functional form in the microchannel. By applying the hydraulic head difference and controlling revolution of the revolving mechanisms based on Fourier cosine series, a minute and precise pulsatile flow of a wave functional form may be implemented by means of simple configuration and fabrication, which may not easily obtained by a conventional pump.

    Abstract translation: 用于产生脉冲流的装置包括能够容纳液体的液体容器,与其相关联的多个旋转机构和从液体容器供应液体的微通道。 当多个旋转机构旋转时,在液体容器和微通道之间出现周期性变化的压差,从而在微通道中实现具有波函数形式的脉动流。 通过应用基于傅立叶余弦系列的旋转机构的液压头差和控制旋转,可以通过简单的构造和制造实现波函数形式的微小和精确的脉动流,这可能不容易由常规泵 。

    Apparatus and method for cell particle sorting based on microfluidic-chip flows

    公开(公告)号:US12228496B2

    公开(公告)日:2025-02-18

    申请号:US17083299

    申请日:2020-10-29

    Abstract: Provided is an apparatus for cell particle sorting based on microfluidic-chip flow, by using a design in which Dean flow focusing occurring in a spiral channel and hydrodynamic filtration are coupled. The apparatus comprises a first substrate including a spiral channel having an inner surface and an outer surface based on a radius of curvature, a sample solution inlet, a medium inlet, and a spiral inner-outlet and a spiral outer-outlet both for discharging the particles, and a second substrate including a main channel in which the sample solution discharged from the first substrate and passing through an inter-substrate way flows and a cut-off width WC is set, a side channel allowing a medium introduced into the medium inlet to flow to focus the sample solution on a sidewall of the main channel, a plurality of branch channels connected to the sidewall of main channel and configured to receive the particles from the main channel, a main channel outlet, and at least one branch channel outlet.

Patent Agency Ranking