公开(公告)号：US20170204056A1

公开(公告)日：2017-07-20

申请号：US15515142

申请日：2015-10-08

Applicant: KYOWA HAKKO BIO CO., LTD.

Inventor： Tetsuro UJIHARA ,  Satoshi MITSUHASHI

IPC: C07C401/00 ,  B01J19/12 ,  C12N9/10 ,  C12P33/00 ,  C12P7/22

CPC classification number: C07C401/00 ,  B01J19/123 ,  B01J2219/12 ,  C12N9/1007 ,  C12N15/09 ,  C12P7/22 ,  C12P33/00 ,  C12Y201/01041

Abstract: According to the present invention, there can be provided a process for producing 7-dehydrocholesterol (7DHC), comprising culturing, in a medium, a 7DHC-producing Labyrinthulea microorganism in which sterol 24-C-methyltransferase activity is reduced or lost as compared to a parent strain, allowing 7DHC to be produced and accumulated in the culture, and collecting the 7DHC from the culture; and a process for producing vitamin D3, comprising irradiating, with ultraviolet light, 7-dehydrocholesterol produced by the production process.