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公开(公告)号:US20130261715A1
公开(公告)日:2013-10-03
申请号:US13789602
申请日:2013-03-07
申请人: Kimberly A. Chaffin , Matthew Jolly , Darrel F. Untereker , Adam J. Buckalew , Xiangji Chen , Thomas P. Grailer , Julie Alkatout
发明人: Kimberly A. Chaffin , Matthew Jolly , Darrel F. Untereker , Adam J. Buckalew , Xiangji Chen , Thomas P. Grailer , Julie Alkatout
IPC分类号: A61N1/05
摘要: Medical leads, such as medical electrical leads and medical neurological leads, that include a polymeric material that includes a silicone-urethane-containing polymer having improved hydrolytic stability.
摘要翻译: 包括包含具有改善的水解稳定性的含硅氧烷聚氨酯的聚合物的聚合物材料的医疗引线,例如医用电线和医学神经导线。
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公开(公告)号:US09416210B2
公开(公告)日:2016-08-16
申请号:US13131665
申请日:2009-12-11
申请人: Todd Emrick , Xiangji Chen , Samantha McRae
发明人: Todd Emrick , Xiangji Chen , Samantha McRae
IPC分类号: C08F230/02 , C08F238/00 , A61K47/32 , A61K47/48 , C08F8/30 , C08F220/34 , C08F293/00
CPC分类号: A61K47/48176 , A61K31/4745 , A61K31/704 , A61K47/58 , C08F8/30 , C08F220/34 , C08F230/02 , C08F238/00 , C08F293/005 , C08F2438/01 , C08F220/10
摘要: The invention generally relates to zwitterionic polymers (including zwitterionic copolymers), such as polymethacrylic structures, with pendent functional moieties, such as therapeutic or biologic moieties. More particularly, the invention relates to phosphorylcholine-substituted methacrylic polymers prepared by free radical polymerization and click chemistry, for example, and compositions and products comprising same, as well as related methods and uses of the compositions, for example, as biological or therapeutic agents and in drug delivery thereof.
摘要翻译: 本发明一般涉及两性离子聚合物(包括两性离子共聚物),例如聚甲基丙烯酸结构,其具有悬挂的功能部分,例如治疗或生物学部分。 更具体地,本发明涉及通过自由基聚合和点击化学制备的磷酸胆碱取代的甲基丙烯酸聚合物,以及包含其的组合物和产品,以及组合物的相关方法和用途,例如作为生物或治疗剂 并在其药物递送中。
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公开(公告)号:US20110319569A1
公开(公告)日:2011-12-29
申请号:US13131665
申请日:2009-12-11
申请人: Todd Emrick , Xiangji Chen , Samantha McRae
发明人: Todd Emrick , Xiangji Chen , Samantha McRae
IPC分类号: C08F293/00 , C08F30/02 , C08F120/14 , C08F230/02 , C08H1/00
CPC分类号: A61K47/48176 , A61K31/4745 , A61K31/704 , A61K47/58 , C08F8/30 , C08F220/34 , C08F230/02 , C08F238/00 , C08F293/005 , C08F2438/01 , C08F220/10
摘要: The invention generally relates to zwitterionic polymers (including zwitterionic copolymers), such as polymethacrylic structures, with pendent functional moieties, such as therapeutic or biologic moieties. More particularly, the invention relates to phosphorylcholine-substituted methacrylic polymers prepared by free radical polymerization and click chemistry, for example, and compositions and products comprising same, as well as related methods and uses of the compositions, for example, as biological or therapeutic agents and in drug delivery thereof.
摘要翻译: 本发明一般涉及两性离子聚合物(包括两性离子共聚物),例如聚甲基丙烯酸结构,其具有悬挂的功能部分,例如治疗或生物学部分。 更具体地,本发明涉及通过自由基聚合和点击化学制备的磷酸胆碱取代的甲基丙烯酸聚合物,以及包含其的组合物和产品,以及组合物的相关方法和用途,例如作为生物或治疗剂 并在其药物递送中。
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