公开(公告)号：US20170177792A1

公开(公告)日：2017-06-22

申请号：US15128859

申请日：2015-03-24

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Nivedita Sumi MAJUMDAR ,  Harrison LEONG ,  Shakila POTHINI ,  David HOARD ,  Christopher FONG ,  Pratik Simon SOARES ,  Salil KUMAR ,  Thomas WESSEL ,  Manjula ALIMINATI ,  Levente EGRY

IPC: G06F19/28 ,  G06F19/26 ,  G06F17/30 ,  G06F19/22

CPC classification number: G16B50/00 ,  G06F16/951 ,  G16B30/00 ,  G16B45/00

Abstract: A system for analyzing biological data, comprising: a storage configured to store a plurality of data files containing biological data obtained from a plurality of devices; a server configured to: host a plurality of applications, each configured to be implemented on the server and to provide analysis, manipulation, comparison, visualization, or a combination thereof, of the biological data included in the data files, wherein the plurality of applications allow a user to analyze different data files related to the same sample and compare the results of the analysis.

公开(公告)号：US20200074303A1

公开(公告)日：2020-03-05

申请号：US16555803

申请日：2019-08-29

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Yong CHU ,  Nivedita MAJUMBAR ,  Manjula ALIMINATI ,  Yongzhi CHEN ,  Kevin PAPENFUSS

IPC: G06N3/08 ,  G06N3/04

Abstract: A system and methods are provided for image driven quality control for array based PCR. The system comprises a PCR unit, a reaction array plate, a convolutional neural network (CNN) configured to receive a sequence of images of the reaction array plate in the PCR system, and an output of the CNN coupled to a control for the reaction array plate. The method comprises applying a sequence of images from a plurality of subarrays of the reaction array plate to a plurality of CNNs during operation of the PCR system on the reaction plate array, operating the CNNs to generate failure mode predictions for the reaction plate based on the sequence of images, and coupling an output of the CNNs to one or more of a setting for manufacture of the reaction array plate or to control the PCR system.

公开(公告)号：US20190170684A1

公开(公告)日：2019-06-06

申请号：US16265806

申请日：2019-02-01

Applicant: Life Technologies Corporation

Inventor： David DENNY ,  David WOO ,  Manjula ALIMINATI ,  Siva Kumar SAMSANI ,  Stephanie SCHNEIDER ,  Yoke Peng LIM ,  Sylvia CHANG

IPC: G01N27/447 ,  G16B30/00

CPC classification number: G01N27/44717 ,  G16B30/00

Abstract: In one exemplary embodiment, a method for detecting variants in electropherogram data is provided. The method includes receiving electropherogram data from an instrument and analyzing the electropherogram data to identify mixed bases in the electropherogram data. The method further includes validating the identified mixed bases. Then the method includes determining variants in the electropherogram data based on the validated mixed bases.