公开(公告)号：US20180144094A1

公开(公告)日：2018-05-24

申请号：US15579407

申请日：2016-06-03

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Nivedita Sumi MAJUMDAR ,  Thomas WESSEL

IPC: G06F19/24 ,  G06N7/00

CPC classification number: G16B40/00 ,  G06N7/005

Abstract: A method for determining false positives calls in a biological data plot is provided. The method includes identifying a first data cluster as non-amplification data points within the biological data plot and identifying a second data cluster as wild-type positives within the biological data plot. The method further includes estimating a position in the biological data plot of a center of the first and second data clusters. The method further includes determining, for each data point within the first data cluster, a probability of belonging to the first data cluster and determining, for each data point within the second data cluster, a probability of belonging to the second data cluster. The method includes applying a probability threshold for each data point within the first and second data cluster to identify false positives.

公开(公告)号：US20170177792A1

公开(公告)日：2017-06-22

申请号：US15128859

申请日：2015-03-24

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Nivedita Sumi MAJUMDAR ,  Harrison LEONG ,  Shakila POTHINI ,  David HOARD ,  Christopher FONG ,  Pratik Simon SOARES ,  Salil KUMAR ,  Thomas WESSEL ,  Manjula ALIMINATI ,  Levente EGRY

IPC: G06F19/28 ,  G06F19/26 ,  G06F17/30 ,  G06F19/22

CPC classification number: G16B50/00 ,  G06F16/951 ,  G16B30/00 ,  G16B45/00

Abstract: A system for analyzing biological data, comprising: a storage configured to store a plurality of data files containing biological data obtained from a plurality of devices; a server configured to: host a plurality of applications, each configured to be implemented on the server and to provide analysis, manipulation, comparison, visualization, or a combination thereof, of the biological data included in the data files, wherein the plurality of applications allow a user to analyze different data files related to the same sample and compare the results of the analysis.

公开(公告)号：US20190126281A1

公开(公告)日：2019-05-02

申请号：US16116801

申请日：2018-08-29

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Yong CHU ,  Jeffrey MARKS ,  Jacob FREUDENTHAL ,  Mingsong CHEN ,  Tiong Han TOH ,  Mauro AGUANNO ,  Lik Seng LAU ,  Lian Seng LOH ,  Kok Siong TEO ,  Zeng Wei CHU ,  Xin MATHERS ,  Michael UY ,  Huei Steven YEO ,  Kuan Moon BOO ,  Way Xuang LEE ,  Chin Yong KOO ,  Wei Fuh TEO ,  Soo Yong LAU ,  Hon Siu SHIN ,  Zeqi TAN ,  Thomas WESSEL ,  David WOO

IPC: B01L7/00 ,  G01N21/27 ,  G01N21/64 ,  C12Q1/6806 ,  G01N35/02

Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.