公开(公告)号：US10076566B2

公开(公告)日：2018-09-18

申请号：US15084108

申请日：2016-03-29

Applicant: MERIAL, INC.

Inventor： Jean-Christophe Audonnet ,  Jules Minke

IPC: A61K39/175 ,  C12N7/00 ,  A61K39/12 ,  C07K14/005 ,  C07K14/535 ,  A61N5/06 ,  A61K39/00

CPC classification number: A61K39/175 ,  A61K39/12 ,  A61K2039/53 ,  A61K2039/545 ,  A61K2039/552 ,  A61K2039/55522 ,  A61N5/0613 ,  C07K14/005 ,  C07K14/535 ,  C12N7/00 ,  C12N2710/24043 ,  C12N2750/14334 ,  C12N2760/18422 ,  C12N2760/18434 ,  C12N2760/18471 ,  C12N2800/22

Abstract: The present invention provides vectors that contain and express in vivo or in vitro CDV polypeptides or antigens that elicit an immune response in animal against CDV, compositions comprising said vectors and/or CDV polypeptides, and methods of vaccination against CDV. The invention further provides methods for inducing an immunogenic or protective response against CDV and other canine virus, as well as methods for preventing or treating CDV and other canine virus or disease state(s) caused by CDV and other canine virus.

公开(公告)号：US20160199483A1

公开(公告)日：2016-07-14

申请号：US15084108

申请日：2016-03-29

Applicant: MERIAL, INC.

Inventor： Jean-Christophe Audonnet ,  Jules Minke

IPC: A61K39/175 ,  C07K14/535 ,  C12N7/00 ,  C07K14/005

CPC classification number: A61K39/175 ,  A61K39/12 ,  A61K2039/53 ,  A61K2039/545 ,  A61K2039/552 ,  A61K2039/55522 ,  A61N5/0613 ,  C07K14/005 ,  C07K14/535 ,  C12N7/00 ,  C12N2710/24043 ,  C12N2750/14334 ,  C12N2760/18422 ,  C12N2760/18434 ,  C12N2760/18471 ,  C12N2800/22

Abstract: The present invention provides vectors that contain and express in vivo or in vitro CDV polypeptides or antigens that elicit an immune response in animal against CDV, compositions comprising said vectors and/or CDV polypeptides, and methods of vaccination against CDV. The invention further provides methods for inducing an immunogenic or protective response against CDV and other canine virus, as well as methods for preventing or treating CDV and other canine virus or disease state(s) caused by CDV and other canine virus.

Abstract translation: 本发明提供载体，其含有体内或体外CDV多肽或在动物体内产生针对CDV的免疫应答的抗原，包含所述载体和/或CDV多肽的组合物，以及针对CDV的疫苗接种方法。 本发明还提供了诱导针对CDV和其他犬病毒的免疫原性或保护性应答的方法，以及用于预防或治疗CDV和其他犬病毒或由CDV和其他犬病毒引起的疾病状态的方法。