公开(公告)号：US20190002893A1

公开(公告)日：2019-01-03

申请号：US16023525

申请日：2018-06-29

Applicant: MODERN MEADOW, INC.

Inventor： Lixin Dai ,  Julia Borden ,  Jeffrey Nelson ,  Kristin Ruebling-Jass

IPC: C12N15/81 ,  C07K14/78 ,  D01F4/00 ,  D06N3/00

Abstract: Strains of yeast genetically engineered to produce increased amounts of non-hydroxylated collagen or hydroxylated collagen are described. An all-in-one vector including the DNA necessary to produce collagen, promotors, and hydroxylating enzymes is also described. Methods for producing non-hydroxylated or hydroxylated collagen are also provided.

公开(公告)号：US11312968B2

公开(公告)日：2022-04-26

申请号：US16023525

申请日：2018-06-29

Applicant: MODERN MEADOW, INC.

Inventor： Lixin Dai ,  Julia Borden ,  Jeffrey Nelson ,  Kristin Ruebling-Jass

IPC: C12Q1/68 ,  C12N15/81 ,  C07K14/78 ,  C12P21/02 ,  C08J3/24 ,  C12N1/16 ,  C12N1/18 ,  C12R1/72 ,  C12R1/78 ,  C12R1/84 ,  C12R1/85 ,  D01F4/00 ,  D06N3/00 ,  C12N9/02 ,  C12N15/10

Abstract: Strains of yeast genetically engineered to produce increased amounts of non-hydroxylated collagen or hydroxylated collagen are described. An all-in-one vector including the DNA necessary to produce collagen, promotors, and hydroxylating enzymes is also described. Methods for producing non-hydroxylated or hydroxylated collagen are also provided.