公开(公告)号：US11891375B2

公开(公告)日：2024-02-06

申请号：US17814815

申请日：2022-07-25

Applicant: MOEHS IBERICA, S.L.

Inventor： Abdeslam Akhatou ,  Alicia Dobarro Rodríguez

IPC: C07D401/12 ,  C07C201/14 ,  C07D239/34 ,  C07D239/36

CPC classification number: C07D401/12 ,  C07C201/14 ,  C07D239/34 ,  C07D239/36 ,  C07B2200/13

Abstract: A method is for the synthesis of 2,4-dimethylpyrimidin-5-ol, which can be used as an intermediate compound in the synthesis of Lemborexant. The method includes reacting a nitrophenyl compound with N,N-dimethylformamide diethyl acetal.