公开(公告)号：US06997925B2

公开(公告)日：2006-02-14

申请号：US10274729

申请日：2002-10-21

申请人： Mark A. Maguire ,  Michael D. Lesh ,  James C. Peacock, III ,  Edward L. Carcamo

发明人： Mark A. Maguire ,  Michael D. Lesh ,  James C. Peacock, III ,  Edward L. Carcamo

IPC分类号： A61B18/18

CPC分类号： A61B18/1492 ,  A61B18/00 ,  A61B18/08 ,  A61B18/1815 ,  A61B2017/00243 ,  A61B2017/22038 ,  A61B2017/22054 ,  A61B2017/22067 ,  A61B2018/00011 ,  A61B2018/00065 ,  A61B2018/00101 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00238 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00369 ,  A61B2018/00375 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61B2018/00994 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2218/002 ,  A61M25/1002 ,  A61N7/02

摘要： This invention is related to a tissue ablation system and method that treats atrial arrhythmia by ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium. The system includes a circumferential ablation member with an ablation element and also includes a delivery assembly for delivering the ablation member to the location. The circumferential ablation member is generally adjustable between different configurations to allow both the delivery through a delivery sheath into the atrium and the ablative coupling between the ablation element and the circumferential region of tissue.

公开(公告)号：US07340307B2

公开(公告)日：2008-03-04

申请号：US10996523

申请日：2004-11-24

申请人： Mark A. Maguire ,  Michael D. Lesh ,  James C. Peacock, III ,  Edward L. Carcamo

发明人： Mark A. Maguire ,  Michael D. Lesh ,  James C. Peacock, III ,  Edward L. Carcamo

IPC分类号： A61B18/18

CPC分类号： A61N7/02 ,  A61B18/00 ,  A61B18/08 ,  A61B18/1492 ,  A61B2017/00243 ,  A61B2018/00011 ,  A61B2018/00065 ,  A61B2018/00101 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00238 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2218/002 ,  A61M25/1002

摘要： This invention is related to a tissue ablation system and method that treats atrial arrhythmia by ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium. The system includes a circumferential ablation member with an ablation element and also includes a delivery assembly for delivering the ablation member to the location. The circumferential ablation member is generally adjustable between different configurations to allow both the delivery through a delivery sheath into the atrium and the ablative coupling between the ablation element and the circumferential region of tissue.

摘要翻译： 本发明涉及组织消融系统和方法，其通过在肺静脉从心房延伸的位置烧蚀组织的周边区域来治疗心律失常。 该系统包括具有消融元件的圆周消融构件，并且还包括用于将消融构件输送到该位置的输送组件。 圆周消融部件通常在不同构型之间是可调节的，以允许通过输送护套输送到心房中，以及消融元件与组织的圆周区域之间的消融耦合。

公开(公告)号：US06964660B2

公开(公告)日：2005-11-15

申请号：US10274742

申请日：2002-10-21

申请人： Mark A. Maguire ,  Michael D. Lesh ,  James C. Peacock, III ,  Edward L. Carcamo

发明人： Mark A. Maguire ,  Michael D. Lesh ,  James C. Peacock, III ,  Edward L. Carcamo

IPC分类号： A61B17/00 ,  A61B18/00 ,  A61B18/08 ,  A61B18/14 ,  A61F2/958 ,  A61N7/02 ,  A61B18/18

CPC分类号： A61N7/02 ,  A61B18/00 ,  A61B18/08 ,  A61B18/1492 ,  A61B2017/00243 ,  A61B2018/00011 ,  A61B2018/00065 ,  A61B2018/00101 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00238 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2218/002 ,  A61M25/1002

摘要： This invention is related to a tissue ablation system and method that treats atrial arrhythmia by ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium. The system includes a circumferential ablation member with an ablation element and also includes a delivery assembly for delivering the ablation member to the location. The circumferential ablation member is generally adjustable between different configurations to allow both the delivery through a delivery sheath into the atrium and the ablative coupling between the ablation element and the circumferential region of tissue.

摘要翻译： 本发明涉及组织消融系统和方法，其通过在肺静脉从心房延伸的位置烧蚀组织的周边区域来治疗心律失常。 该系统包括具有消融元件的圆周消融构件，并且还包括用于将消融构件输送到该位置的输送组件。 圆周消融部件通常在不同构型之间是可调节的，以允许通过输送护套输送到心房中，以及消融元件与组织的圆周区域之间的消融耦合。

公开(公告)号：US06652515B1

公开(公告)日：2003-11-25

申请号：US09435281

申请日：1999-11-05

申请人： Mark A. Maguire ,  Michael D. Lesh ,  James C. Peacock, III ,  Edward L. Carcamo

发明人： Mark A. Maguire ,  Michael D. Lesh ,  James C. Peacock, III ,  Edward L. Carcamo

IPC分类号： A61B1818

CPC分类号： A61N7/02 ,  A61B18/00 ,  A61B18/08 ,  A61B18/1492 ,  A61B2017/00243 ,  A61B2018/00011 ,  A61B2018/00065 ,  A61B2018/00101 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00238 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2218/002 ,  A61M25/1002

摘要： This invention is related to a tissue ablation system and method that treats atrial arrhythmia by ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium. The system includes a circumferential ablation member with an ablation element and also includes a delivery assembly for delivering the ablation member to the location. The circumferential ablation member is generally adjustable between different configurations to allow both the delivery through a delivery sheath into the atrium and the ablative coupling between the ablation element and the circumferential region of tissue.

公开(公告)号：US06966908B2

公开(公告)日：2005-11-22

申请号：US10274767

申请日：2002-10-21

申请人： Mark A. Maguire ,  Michael D. Lesh ,  James C. Peacock, III ,  Edward L. Carcamo

发明人： Mark A. Maguire ,  Michael D. Lesh ,  James C. Peacock, III ,  Edward L. Carcamo

IPC分类号： A61B17/00 ,  A61B18/00 ,  A61B18/08 ,  A61B18/14 ,  A61F2/958 ,  A61N7/02 ,  A61B18/18

CPC分类号： A61B18/00 ,  A61B18/08 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2017/00243 ,  A61B2017/22038 ,  A61B2017/22054 ,  A61B2017/22067 ,  A61B2018/00011 ,  A61B2018/00065 ,  A61B2018/00101 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00238 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00369 ,  A61B2018/00375 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61B2018/00994 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2218/002 ,  A61M25/1002 ,  A61N7/02

摘要： This invention is related to a tissue ablation system and method that treats atrial arrhythmia by ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium. The system includes a circumferential ablation member with an ablation element and also includes a delivery assembly for delivering the ablation member to the location. The circumferential ablation member is generally adjustable between different configurations to allow both the delivery through a delivery sheath into the atrium and the ablative coupling between the ablation element and the circumferential region of tissue.

公开(公告)号：US06547788B1

公开(公告)日：2003-04-15

申请号：US09517614

申请日：2000-03-02

申请人： Mark A. Maguire ,  Martin F. O'Sullivan ,  Edward L. Carcamo ,  Michael D. Lesh ,  Alan K. Schaer ,  Kevin J. Taylor ,  Guillermo P. Picazo

发明人： Mark A. Maguire ,  Martin F. O'Sullivan ,  Edward L. Carcamo ,  Michael D. Lesh ,  Alan K. Schaer ,  Kevin J. Taylor ,  Guillermo P. Picazo

IPC分类号： A61B1818

CPC分类号： A61B18/00 ,  A61B18/1492 ,  A61B2017/00243 ,  A61B2018/00083 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61M25/1002 ,  A61M2210/125 ,  A61N7/02 ,  A61N7/022

摘要： A tissue ablation catheter for forming a lesion along a substantially circumferential region of tissue is described. The catheter includes one or more sensors for monitoring the temperature of the tissue being ablated. The temperature sensors are mounted on the interior or exterior of an expandable member that is affixed to a shaft of the catheter.

摘要翻译： 描述了用于沿着组织的基本圆周区域形成病变的组织消融导管。 该导管包括一个或多个传感器，用于监测被消融的组织的温度。 温度传感器安装在固定到导管的轴上的可扩张构件的内部或外部。

公开(公告)号：US06869431B2

公开(公告)日：2005-03-22

申请号：US09949479

申请日：2001-09-07

申请人： Mark A. Maguire ,  Martin F. O'Sullivan ,  Edward L. Carcamo ,  Michael D. Lesh ,  Alan K. Schaer ,  Kevin J. Taylor ,  Guillermo P. Picazo

发明人： Mark A. Maguire ,  Martin F. O'Sullivan ,  Edward L. Carcamo ,  Michael D. Lesh ,  Alan K. Schaer ,  Kevin J. Taylor ,  Guillermo P. Picazo

IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B18/00 ,  A61B18/14 ,  A61B19/00 ,  A61N7/02 ,  A61B18/18

CPC分类号： A61B18/00 ,  A61B18/1492 ,  A61B2017/00092 ,  A61B2017/00243 ,  A61B2017/00526 ,  A61B2017/22051 ,  A61B2017/22067 ,  A61B2018/00065 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00285 ,  A61B2018/00357 ,  A61B2018/00369 ,  A61B2018/00375 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/1253 ,  A61B2090/3784 ,  A61N7/02

摘要： Disclosed is a method for attaching a sensor to an inflatable balloon. The method involves bonding the sensor to the balloon with an adhesive while the balloon is in an expanded state and then collapsing the balloon after the adhesive has at least partially cured. The method reduces the possibility of a failure of the bond between the sensor and the balloon. The method is particularly useful in the construction of a tissue ablation catheter for forming a lesion along a substantially circumferential region of tissue wherein a sensor is used for monitoring the temperature of the tissue being ablated.

摘要翻译： 公开了一种将传感器附接到可充气球囊的方法。 该方法包括使用粘合剂将传感器粘合到球囊上，同时气囊处于膨胀状态，然后在粘合剂具有至少部分固化之后使囊膨胀。 该方法降低了传感器和气囊之间的接合故障的可能性。 该方法特别可用于组织消融导管的构造，用于沿着组织的基本圆周区域形成病变，其中传感器用于监测被消融的组织的温度。

公开(公告)号：US06953460B2

公开(公告)日：2005-10-11

申请号：US10356418

申请日：2003-01-31

申请人： Mark A. Maguire ,  Martin F. O'Sullivan ,  Edward L. Carcamo ,  Michael D. Lesh ,  Alan K. Schaer ,  Kevin J. Taylor ,  Guillermo P. Picazo

发明人： Mark A. Maguire ,  Martin F. O'Sullivan ,  Edward L. Carcamo ,  Michael D. Lesh ,  Alan K. Schaer ,  Kevin J. Taylor ,  Guillermo P. Picazo

IPC分类号： A61B17/00 ,  A61B18/00 ,  A61B18/18 ,  A61N7/02 ,  A61B10/04

CPC分类号： A61B18/00 ,  A61B18/1492 ,  A61B2017/00243 ,  A61B2018/00083 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61M25/1002 ,  A61M2210/125 ,  A61N7/02 ,  A61N7/022

摘要： A tissue ablation catheter for forming a lesion along a substantially circumferential region of tissue is described. The catheter includes one or more sensors for monitoring the temperature of the tissue being ablated. The temperature sensors are mounted on the interior or exterior of an expandable member that is affixed to a shaft of the catheter.

摘要翻译： 描述了用于沿着组织的基本圆周区域形成病变的组织消融导管。 该导管包括一个或多个传感器，用于监测被消融的组织的温度。 温度传感器安装在固定到导管的轴上的可扩张构件的内部或外部。

公开(公告)号：US06514249B1

公开(公告)日：2003-02-04

申请号：US09517472

申请日：2000-03-02

申请人： Mark A. Maguire ,  Martin F. O'Sullivan ,  Edward L. Carcamo ,  Michael D. Lesh ,  Alan K. Schaer ,  Kevin J. Taylor ,  Guillermo P. Picazo

发明人： Mark A. Maguire ,  Martin F. O'Sullivan ,  Edward L. Carcamo ,  Michael D. Lesh ,  Alan K. Schaer ,  Kevin J. Taylor ,  Guillermo P. Picazo

IPC分类号： A61B1818

CPC分类号： A61N7/02 ,  A61B18/00 ,  A61B18/1492 ,  A61B2017/00106 ,  A61B2017/00243 ,  A61B2018/00214 ,  A61B2018/00261

摘要： This invention relates to a surgical device and method. More particularly, it relates to a tissue ablation device assembly and method using a circumferential ablation member in combination with a position monitoring assembly in order to position the circumferential ablation member along a circumferential region of tissue at a location where a pulmonary vein extends from a left atrium.

摘要翻译： 本发明涉及一种手术装置和方法。 更具体地，本发明涉及一种组织消融装置组件和使用周边消融部件与位置监测组件组合的方法，以便沿着肺静脉从左侧延伸的位置沿着组织的周边区域定位周边消融部件 心房

公开(公告)号：US06383151B1

公开(公告)日：2002-05-07

申请号：US09659477

申请日：2000-09-11

申请人： Chris J. Diederich ,  Michael D. Lesh ,  James C. Peacock, III ,  Michael R. Ross

发明人： Chris J. Diederich ,  Michael D. Lesh ,  James C. Peacock, III ,  Michael R. Ross

IPC分类号： A61B100

CPC分类号： A61B18/1492 ,  A61B18/00 ,  A61B2017/00243 ,  A61B2018/00083 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61M25/1002 ,  A61M2210/125 ,  A61N7/02 ,  A61N7/022

摘要： This invention is a circumferential ablation device assembly which is adapted to forming a circumferential conduction block in a pulmonary vein. The assembly includes a circumferential ablation element which is adapted to ablate a circumferential region of tissue along a pulmonary vein wall which circumscribes the pulmonary vein lumen, thereby transecting the electrical conductivity of the pulmonary vein against conduction along its longitudinal axis and into the left atrium. The circumferential ablation element includes an expandable member with a working length that is adjustable from a radially collapsed position to a radially expanded position. An equatorial band circumscribes the outer surface of the working length and is adapted to ablate tissue adjacent thereto when actuated by an ablation actuator. The equatorial band has a length relative to the longitudinal axis of the expandable member that is narrow relative to the working length, and is also substantially shorter than its circumference when the working length is in the radially expanded position. A pattern of insulators may be included over an ablation element which otherwise spans the working length in order to form the equatorial band described. The expandable member is also adapted to conform to the pulmonary vein in the region of its ostium, such as by providing a great deal of radial compliance or by providing a taper along the working length which has a distally reducing outer diameter. A linear ablation element is provided adjacent to the circumferential ablation element in a combination assembly which is adapted for use in a less-invasive “maze”-type procedure in the region of the pulmonary vein ostia in the left ventricle. A cylindrical ultrasound transducer is provided on an inner member within the balloon and forms the circumferential ablation member by emitting a radial ultrasound signal which is circumferential to the transducer and highly collimated to the transducer's length. The circumferential ultrasound signal sonically couples to the balloon's outer skin to form the circumferential ablation element that is adapted to ablate a circumferential path of tissue engaged to the balloon.