公开(公告)号：US11768262B2

公开(公告)日：2023-09-26

申请号：US16818588

申请日：2020-03-13

Applicant: Massachusetts Institute of Technology

Inventor： Virginia Spanoudaki ,  Aviad Hai ,  Alan Pradip Jasanoff ,  Daniel G. Anderson ,  Robert S. Langer

IPC: G01R33/36 ,  H01L29/06 ,  H01L27/088

CPC classification number: G01R33/36 ,  H01L29/0673 ,  H01L27/0886

Abstract: A cross-modal interface includes a multi-modal sensor configured to concurrently receive multiple input signals with each input signal being provided from a different imaging modality and in response thereto providing a single cross-modal output signal to processing circuitry which processes the single cross-modal output signal provided thereto and generates an output comprising information obtained or otherwise derived from each of or a combination of the different imaging modalities.

公开(公告)号：US11490814B2

公开(公告)日：2022-11-08

申请号：US16536398

申请日：2019-08-09

Applicant: Massachusetts Institute of Technology

Inventor： Alan Pradip Jasanoff ,  Virginia Spanoudaki ,  Aviad Hai

IPC: A61B5/1473 ,  A61B5/055 ,  A61B5/00 ,  G01R33/48 ,  G01R33/34 ,  G01R33/36 ,  G01N27/414 ,  A61B5/05 ,  H01L31/113 ,  H01Q1/22

Abstract: Embodiments described herein relate to detectors and their method of use for sensing electromagnetic fields, electromagnetic signals, biochemical analytes, and/or other conditions in subjects. The device may include an inductively-coupled implantable coil-based transducer that converts electrical, photonic, biochemical signals, and/or other appropriate signals and/or conditions originating in tissues and/or transplanted tissue grafts into changes in a property of the transducer, such as a resonance frequency, that may be detected using an alternating magnetic field that may be provided by a magnetic resonance imaging (MRI) signal and/or other appropriate source. In some embodiments, the detector comprises a FET that changes state upon detection of a subject condition of interest. The change in the FET may change the resonance frequency of an associated LC or RLC circuit. The change in resonance frequency may change the brightness and/or intensity of the detector when detected by an MRI scanner or other appropriate scanner.

公开(公告)号：US09972649B2

公开(公告)日：2018-05-15

申请号：US15294914

申请日：2016-10-17

Applicant: Massachusetts Institute of Technology

Inventor： Virginia Spanoudaki ,  Daniel G. Anderson ,  Robert S. Langer

IPC: H01L27/146 ,  H01L29/06

CPC classification number: H01L27/14616 ,  G01T1/2018 ,  G01T1/241 ,  G01T1/247 ,  H01L27/14605 ,  H01L27/14636 ,  H01L29/0669

Abstract: A sensor comprises a substrate; an array of nanowire field effect transistors (NWFETs) formed in said substrate, each of the NWFETs having source, drain and gate terminals; a nanowire coupled between the source terminal and the drain terminal of each NWFET; and a layer of radiation sensitive material disposed over said NWFETs and said nanowires with each of the source, drain and gate terminals configured to be coupled to respective ones of first, second or third reference potentials, wherein each NWFET is configured such that the conductivity between the source and drain changes in response to radiation absorbed in the layer of radiation sensitive material such that the sensor generates an output signal in response to radiation absorbed by the radiation sensitive material.

公开(公告)号：US20200046224A1

公开(公告)日：2020-02-13

申请号：US16536398

申请日：2019-08-09

Applicant: Massachusetts Institute of Technology

Inventor： Alan Pradip Jasanoff ,  Virginia Spanoudaki ,  Aviad Hai

IPC: A61B5/00 ,  G01R33/48 ,  G01R33/34 ,  G01R33/36 ,  A61B5/055 ,  A61B5/1473 ,  A61B5/05 ,  H01L31/113 ,  G01N27/414

Abstract: Embodiments described herein relate to detectors and their method of use for sensing electromagnetic fields, electromagnetic signals, biochemical analytes, and/or other conditions in subjects. The device may include an inductively-coupled implantable coil-based transducer that converts electrical, photonic, biochemical signals, and/or other appropriate signals and/or conditions originating in tissues and/or transplanted tissue grafts into changes in a property of the transducer, such as a resonance frequency, that may be detected using an alternating magnetic field that may be provided by a magnetic resonance imaging (MRI) signal and/or other appropriate source. In some embodiments, the detector comprises a FET that changes state upon detection of a subject condition of interest. The change in the FET may change the resonance frequency of an associated LC or RLC circuit. The change in resonance frequency may change the brightness and/or intensity of the detector when detected by an MRI scanner or other appropriate scanner.

公开(公告)号：US20170117312A1

公开(公告)日：2017-04-27

申请号：US15294914

申请日：2016-10-17

Applicant: Massachusetts Institute of Technology

Inventor： Virginia Spanoudaki ,  Daniel G. Anderson ,  Robert S. Langer

IPC: H01L27/146 ,  H01L29/06

CPC classification number: H01L27/14616 ,  G01T1/2018 ,  G01T1/241 ,  G01T1/247 ,  H01L27/14605 ,  H01L27/14636 ,  H01L29/0669

Abstract: A sensor comprises a substrate; an array of nanowire field effect transistors (NWFETs) formed in said substrate, each of the NWFETs having source, drain and gate terminals; a nanowire coupled between the source terminal and the drain terminal of each NWFET; and a layer of radiation sensitive material disposed over said NWFETs and said nanowires with each of the source, drain and gate terminals configured to be coupled to respective ones of first, second or third reference potentials, wherein each NWFET is configured such that the conductivity between the source and drain changes in response to radiation absorbed in the layer of radiation sensitive material such that the sensor generates an output signal in response to radiation absorbed by the radiation sensitive material.