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1.发明申请SELECTIVELY EXPANDABLE OPERATIVE ELEMENT SUPPORT STRUCTURE AND METHODS OF USE 审中-公开选择性可扩展的操作元素支持结构和使用方法公开(公告)号：US20120239028A1
公开(公告)日：2012-09-20
申请号：US13051738
申请日：2011-03-18
CPC分类号： A61B18/1492 , A61B18/06 , A61B18/082 , A61B18/24 , A61B2018/0016 , A61B2018/0022 , A61B2018/00488 , A61B2018/00577 , A61B2018/0212 , A61B2018/1497 , A61B2018/1861 , A61N7/022
摘要： In one embodiment, a device is provided including an expandable support member having a first portion and a second portion is provided. The first portion is adapted to have a smaller expansion index than the second portion. A therapeutic or diagnostic instrument is supported, at least in part, by the expandable support member first portion. In another embodiment, the support member is adapted for non-uniform expansion of the first and second portions. There are also described methods of forming therapeutic devices. There are also described methods of providing therapy to tissue in a body by positioning a device in proximity to tissue in a body selected to receive therapy. Next, the expandable support member second portion is expanded until the instrument is at a therapeutic position relative to the tissue in a body selected to receive therapy. Thereafter, therapy or diagnosis is provided to the selected tissue using the device.
摘要翻译： 在一个实施例中，提供了包括具有第一部分和第二部分的可扩展支撑构件的装置。 第一部分适于具有比第二部分更小的膨胀指数。 治疗或诊断仪器至少部分由可扩张支撑构件第一部分支撑。 在另一个实施例中，支撑构件适于使第一和第二部分不均匀地膨胀。 还描述了形成治疗装置的方法。 还描述了通过将设备定位在选择用于接受治疗的身体中的组织附近来向身体中的组织提供治疗的方法。 接下来，可扩展支撑构件第二部分被扩张，直到器械相对于选择用于接受治疗的身体中的组织处于治疗位置。 此后，使用该装置向所选择的组织提供治疗或诊断。
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公开(公告)号：US10278774B2
公开(公告)日：2019-05-07
申请号：US13051738
申请日：2011-03-18
IPC分类号： A61B18/12 , A61B18/14 , A61B18/00 , A61N7/02 , A61B18/06 , A61B18/08 , A61B18/24 , A61B18/02 , A61B18/18
摘要： In one embodiment, a device is provided including an expandable support member having a first portion and a second portion is provided. The first portion is adapted to have a smaller expansion index than the second portion. A therapeutic or diagnostic instrument is supported, at least in part, by the expandable support member first portion. In another embodiment, the support member is adapted for non-uniform expansion of the first and second portions. There are also described methods of forming therapeutic devices. There are also described methods of providing therapy to tissue in a body by positioning a device in proximity to tissue in a body selected to receive therapy. Next, the expandable support member second portion is expanded until the instrument is at a therapeutic position relative to the tissue in a body selected to receive therapy. Thereafter, therapy or diagnosis is provided to the selected tissue using the device.
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3.发明申请公开(公告)号：US20090012513A1
公开(公告)日：2009-01-08
申请号：US12167931
申请日：2008-07-03
CPC分类号： A61B18/1485 , A61B18/0218 , A61B18/1492 , A61B2017/22069 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00285 , A61B2018/00482 , A61B2018/00494 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00738 , A61B2018/00791 , A61B2018/00875 , A61B2018/00898 , A61B2018/0262 , A61B2018/124 , A61B2018/1497
摘要： Devices and methods are provided for the ablation of regions of the digestive tract to achieve hemostasis and to eradicate chronically bleeding lesions as occur with gastric antral vascular ectasia (GAVE), portal hypertensive gastropathy (PHG), radiation proctopathy and colopathy, arteriovenous malformations, and angiodysplasia. Ablation is typically provided in a wide-field manner, and in conjunction with sufficient pressure to achieve coaptive coagulation. Ablation, as provided the invention, starts at the mucosa and penetrates deeper into the gastrointestinal wall in a controlled manner. Ablation control may be exerted by way of electrode design and size, energy density, power density, number of applications, pattern of applications, and pressure. Control may also be provided by a fractional ablation that ablates some tissue within a target region and leaves a portion substantially unaffected. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.
摘要翻译： 提供了用于消融消化道的设备和方法，以实现止血和根除胃窦血管扩张症（GAVE），门静脉高压性胃病（PHG），放射性原发性病变和病变，动静脉畸形以及 血管发育不良。 通常以广泛的方式提供消融，并结合足够的压力来实现合适的凝血。 根据本发明，消融从粘膜开始并以受控的方式深入胃肠壁。 消融控制可以通过电极设计和尺寸，能量密度，功率密度，应用数量，应用模式和压力来施加。 控制也可以通过消融目标区域内的一些组织并使基本上不受影响的部分的部分消融来提供。 该装置的实施例包括跨越360度的消融电极阵列和跨越小于360度的弧的阵列。
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4.发明授权公开(公告)号：US08439908B2
公开(公告)日：2013-05-14
申请号：US12167931
申请日：2008-07-03
CPC分类号： A61B18/1485 , A61B18/0218 , A61B18/1492 , A61B2017/22069 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00285 , A61B2018/00482 , A61B2018/00494 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00738 , A61B2018/00791 , A61B2018/00875 , A61B2018/00898 , A61B2018/0262 , A61B2018/124 , A61B2018/1497
摘要： Devices and methods are provided for the ablation of regions of the digestive tract to achieve hemostasis and to eradicate chronically bleeding lesions as occur with gastric antral vascular ectasia (GAVE), portal hypertensive gastropathy (PHG), radiation proctopathy and colopathy, arteriovenous malformations, and angiodysplasia. Ablation is typically provided in a wide-field manner, and in conjunction with sufficient pressure to achieve coaptive coagulation. Ablation, as provided the invention, starts at the mucosa and penetrates deeper into the gastrointestinal wall in a controlled manner. Ablation control may be exerted by way of electrode design and size, energy density, power density, number of applications, pattern of applications, and pressure. Control may also be provided by a fractional ablation that ablates some tissue within a target region and leaves a portion substantially unaffected. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.
摘要翻译： 提供了用于消融消化道的设备和方法，以实现止血和根除胃窦血管扩张症（GAVE），门静脉高压性胃病（PHG），放射性原发性病变和病变，动静脉畸形以及 血管发育不良。 通常以广泛的方式提供消融，并结合足够的压力来实现合适的凝血。 根据本发明，消融从粘膜开始并以受控的方式深入胃肠壁。 消融控制可以通过电极设计和尺寸，能量密度，功率密度，应用数量，应用模式和压力来施加。 控制也可以通过消融目标区域内的一些组织并使基本上不受影响的部分的部分消融来提供。 该装置的实施例包括跨越360度的消融电极阵列和跨越小于360度的弧的阵列。
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5.发明申请ELECTRICAL MEANS TO NORMALIZE ABLATIONAL ENERGY TRANSMISSION TO A LUMINAL TISSUE SURFACE OF VARYING SIZE 有权将能量转移到变化尺寸的发光组织表面的电气手段公开(公告)号：US20080319350A1
公开(公告)日：2008-12-25
申请号：US12143404
申请日：2008-06-20
CPC分类号： A61B18/18 , A61B5/053 , A61B5/0538 , A61B5/1076 , A61B18/0218 , A61B18/082 , A61B18/14 , A61B18/1492 , A61B18/20 , A61B2018/00017 , A61B2018/00214 , A61B2018/0022 , A61B2018/00488 , A61B2018/00577 , A61B2018/00642 , A61B2018/00714 , A61B2018/00755 , A61B2018/00791 , A61B2018/00875 , A61B2562/0257
摘要： Methods and devices for measuring the size of a body lumen and a method for ablating tissue that uses the measurement to normalize delivery of ablational energy from an expandable operative element to a luminal target of varying circumference are provided. The method includes inserting into the lumen an expandable operative element having circuitry with resistivity or inductance that varies according to the circumference of the operative element, varying the expansion of the operative element with an expansion medium, measuring the resistivity of the circuitry, and relating the resistivity or inductance to a value for the circumference of the operative element. In some embodiments the sizing circuit includes a conductive elastomer wrapped around the operative element. Other embodiments of the method apply to operative elements that include an overlapping energy delivery element support in which the overlap varies inversely with respect to the state of expansion, and which is configured with sizing electrodes that sense the amount of the overlap.
摘要翻译： 提供了用于测量体腔尺寸的方法和装置以及用于消融组织的方法和装置，所述方法使用所述测量来将消融能量从可扩张的可操作元件的规则化转变为变化圆周的管腔靶。 该方法包括将具有电阻率或电感的电路的可扩展的操作元件插入到内腔中，所述电路或电感根据操作元件的周长而变化，用膨胀介质改变操作元件的膨胀，测量电路的电阻率， 电阻率或电感值为操作元件圆周的值。 在一些实施例中，施胶电路包括围绕操作元件缠绕的导电弹性体。 该方法的其他实施例适用于包括重叠的能量传递元件支撑件的操作元件，其中重叠相对于膨胀状态反向变化，并且其被配置有感测重叠量的尺寸电极。
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6.发明授权Electrical means to normalize ablational energy transmission to a luminal tissue surface of varying size 有权电气意味着将消融能量传递归一化到不同大小的管腔组织表面公开(公告)号：US08784338B2
公开(公告)日：2014-07-22
申请号：US12143404
申请日：2008-06-20
CPC分类号： A61B18/18 , A61B5/053 , A61B5/0538 , A61B5/1076 , A61B18/0218 , A61B18/082 , A61B18/14 , A61B18/1492 , A61B18/20 , A61B2018/00017 , A61B2018/00214 , A61B2018/0022 , A61B2018/00488 , A61B2018/00577 , A61B2018/00642 , A61B2018/00714 , A61B2018/00755 , A61B2018/00791 , A61B2018/00875 , A61B2562/0257
摘要： Methods and devices for measuring the size of a body lumen and a method for ablating tissue that uses the measurement to normalize delivery of ablational energy from an expandable operative element to a luminal target of varying circumference are provided. The method includes inserting into the lumen an expandable operative element having circuitry with resistivity or inductance that varies according to the circumference of the operative element, varying the expansion of the operative element with an expansion medium, measuring the resistivity of the circuitry, and relating the resistivity or inductance to a value for the circumference of the operative element. In some embodiments the sizing circuit includes a conductive elastomer wrapped around the operative element. Other embodiments of the method apply to operative elements that include an overlapping energy delivery element support in which the overlap varies inversely with respect to the state of expansion, and which is configured with sizing electrodes that sense the amount of the overlap.
摘要翻译： 提供了用于测量体腔尺寸的方法和装置以及用于消融组织的方法和装置，所述方法使用所述测量来将消融能量从可扩张的可操作元件的规则化转变为变化圆周的管腔靶。 该方法包括将具有电阻率或电感的电路的可扩展的操作元件插入到内腔中，所述电路或电感根据操作元件的周长而变化，用膨胀介质改变操作元件的膨胀，测量电路的电阻率， 电阻率或电感值为操作元件圆周的值。 在一些实施例中，施胶电路包括围绕操作元件缠绕的导电弹性体。 该方法的其他实施例适用于包括重叠的能量传递元件支撑件的操作元件，其中重叠相对于膨胀状态反向变化，并且其被配置有感测重叠量的尺寸电极。
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公开(公告)号：US07997278B2
公开(公告)日：2011-08-16
申请号：US11286444
申请日：2005-11-23
IPC分类号： A61B18/12
CPC分类号： A61B18/1492 , A61B18/02 , A61B18/1815 , A61B90/50 , A61B2017/00296 , A61B2018/00285 , A61B2018/00482 , A61B2018/046 , A61B2018/1495
摘要： Methods of ablating tissue in an alimentary tract are provided. The methods include advancing an ablation structure into an alimentary tract while supporting the ablation structure with an endoscope. The methods further include a step of moving at least part of the ablation structure with respect to the endoscope and toward a tissue surface, before activating the ablation structure to ablate a tissue surface.
摘要翻译： 提供了在消化道中消融组织的方法。 所述方法包括将消融结构推进消化道，同时用内窥镜支持消融结构。 所述方法还包括在激活消融结构以消融组织表面之前相对于内窥镜移动至少部分消融结构并朝向组织表面的步骤。
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公开(公告)号：US07959627B2
公开(公告)日：2011-06-14
申请号：US11286257
申请日：2005-11-23
IPC分类号： A61B18/12
CPC分类号： A61B18/1492 , A61B18/18 , A61B2018/00214 , A61B2018/0022 , A61B2018/00577 , A61B2018/1495 , A61B2018/1807
摘要： Apparatus for treating abnormal mucosa in an alimentary tract are provided. The apparatus include an ablation structure configured to be removably coupled to an endoscope and a deflection mechanism adapted to move the ablation structure with respect to the endoscope and toward a tissue surface.
摘要翻译： 提供了用于治疗消化道异常粘膜的装置。 该装置包括被配置为可移除地联接到内窥镜的消融结构和适于使消融结构相对于内窥镜移动并朝向组织表面的偏转机构。
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公开(公告)号：US08702695B2
公开(公告)日：2014-04-22
申请号：US12404159
申请日：2009-03-13
IPC分类号： A61B18/14
CPC分类号： A61B18/18 , A61B18/02 , A61B18/1492 , A61B18/1815 , A61B34/71 , A61B90/50 , A61B2017/00296 , A61B2018/0022 , A61B2018/00285 , A61B2018/00482 , A61B2018/00488 , A61B2018/00577 , A61B2018/046 , A61B2018/1495
摘要： An ablation device and methods for use thereof including a support structure adapted to support an ablation structure within an alimentary tract of a patient are provided. The support structure includes a longitudinal support with a longitudinal axis and a rotational support. The rotational support is adapted to permit at least part of the ablation structure to rotate with respect to the longitudinal support's longitudinal axis.
摘要翻译： 提供消融装置及其使用方法，其包括适于支撑患者消化道内的消融结构的支撑结构。 支撑结构包括具有纵向轴线和旋转支撑件的纵向支撑件。 旋转支撑件适于允许至少部分消融结构相对于纵向支撑件的纵向轴线旋转。
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公开(公告)号：US08702694B2
公开(公告)日：2014-04-22
申请号：US11275244
申请日：2005-12-20
IPC分类号： A61B18/14
CPC分类号： A61B18/18 , A61B18/02 , A61B18/1492 , A61B18/1815 , A61B34/71 , A61B90/50 , A61B2017/00296 , A61B2018/0022 , A61B2018/00285 , A61B2018/00482 , A61B2018/00488 , A61B2018/00577 , A61B2018/046 , A61B2018/1495
摘要： An ablation device and methods for use thereof including a support structure adapted to support an ablation structure within an alimentary tract of a patient are provided. The support structure includes a longitudinal support with a longitudinal axis and a rotational support. The rotational support is adapted to permit at least part of the ablation structure to rotate with respect to the longitudinal support's longitudinal axis.
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