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公开(公告)号：US10399943B2
公开(公告)日：2019-09-03
申请号：US15126392
申请日：2015-03-19
申请人： Mycovia Pharmaceuticals, Inc. , The United States of America, as represented by the Secretary, Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D213/26 , C07D401/06 , C07D213/50 , C07D405/06 , C07D213/30 , C07D213/38
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US10421741B2
公开(公告)日：2019-09-24
申请号：US16030228
申请日：2018-07-09
申请人： Mycovia Pharmaceuticals, Inc. , The United States of America, as represented by the Secretary, Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D405/06 , C07D213/30 , C07D213/38 , C07D213/56 , C07D213/50
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US10407392B2
公开(公告)日：2019-09-10
申请号：US16280527
申请日：2019-02-20
申请人： Mycovia Pharmaceuticals, Inc. , The United States of America as represented by the Secretary, Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D213/26 , C07D213/50 , C07D405/06 , C07D213/38 , C07D213/30 , C07D401/06
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US10173998B2
公开(公告)日：2019-01-08
申请号：US15126402
申请日：2015-03-19
申请人： Mycovia Pharmaceuticals, Inc. , The United States of America, as represented by the Secretary, Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/26 , C07D405/06 , C07D213/38
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US10392365B2
公开(公告)日：2019-08-27
申请号：US16241036
申请日：2019-01-07
申请人： Mycovia Pharmaceuticals, Inc. , The United States of America, as represented by the Secretary, Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D213/26 , C07D401/06 , C07D405/06 , C07D213/38
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US10077250B2
公开(公告)日：2018-09-18
申请号：US15126359
申请日：2015-03-19
申请人： Mycovia Pharmaceuticals, Inc. , The United States of America, as represented by the Secretary Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/56
CPC分类号： C07D401/06 , C07D213/38 , C07D213/50 , C07D213/56 , C07D405/06
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US10414751B2
公开(公告)日：2019-09-17
申请号：US16270717
申请日：2019-02-08
IPC分类号： C07D401/06 , A61P31/10 , C07B63/04
摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.
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公开(公告)号：US10370353B2
公开(公告)日：2019-08-06
申请号：US15835991
申请日：2017-12-08
IPC分类号： C07D401/06
摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.
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公开(公告)号：US20190177298A1
公开(公告)日：2019-06-13
申请号：US16132973
申请日：2018-09-17
申请人： Mycovia Pharmaceuticals, Inc , The U.S.A., as represented by the Secretary, Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/56 , C07D405/06 , C07D213/38 , C07D213/50
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US11247981B2
公开(公告)日：2022-02-15
申请号：US16735094
申请日：2020-01-06
IPC分类号： C07D401/06 , A61K45/06 , C07F9/6524 , C12N9/02
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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