公开(公告)号：US20190210994A1

公开(公告)日：2019-07-11

申请号：US16270717

申请日：2019-02-08

申请人： Mycovia Pharmaceuticals, Inc.

发明人： William J. Hoekstra ,  David Dale Wirth ,  Tracy Ehiwe ,  Thierry Bonnaud

IPC分类号： C07D401/06 ,  C07B63/04 ,  A61P31/10

CPC分类号： C07D401/06 ,  A61P31/10 ,  C07B63/04 ,  C07B2200/13

摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.

公开(公告)号：US20180319768A1

公开(公告)日：2018-11-08

申请号：US15835991

申请日：2017-12-08

申请人： Mycovia Pharmaceuticals, Inc.

发明人： William J. Hoekstra ,  David Dale Wirth ,  Tracy Ehiwe ,  Thierry Bonnaud

IPC分类号： C07D401/06

CPC分类号： C07D401/06 ,  A61P31/10 ,  C07B63/04 ,  C07B2200/13

摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.

公开(公告)号：US10414751B2

公开(公告)日：2019-09-17

申请号：US16270717

申请日：2019-02-08

申请人： Mycovia Pharmaceuticals, Inc.

发明人： William J. Hoekstra ,  David Dale Wirth ,  Tracy Ehiwe ,  Thierry Bonnaud

IPC分类号： C07D401/06 ,  A61P31/10 ,  C07B63/04

摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.

公开(公告)号：US10370353B2

公开(公告)日：2019-08-06

申请号：US15835991

申请日：2017-12-08

申请人： Mycovia Pharmaceuticals, Inc.

发明人： William J. Hoekstra ,  David Dale Wirth ,  Tracy Ehiwe ,  Thierry Bonnaud

IPC分类号： C07D401/06

摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.

公开(公告)号：US10676459B2

公开(公告)日：2020-06-09

申请号：US16545042

申请日：2019-08-20

申请人： MYCOVIA PHARMACEUTICALS INC.

发明人： William J. Hoekstra ,  David Dale Wirth ,  Tracy Ehiwe ,  Thierry Bonnaud

IPC分类号： C07D401/06 ,  A61P31/10 ,  C07B63/04

摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.