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1.发明申请公开(公告)号：US20160168547A1
公开(公告)日：2016-06-16
申请号：US15051169
申请日：2016-02-23
Applicant: Novozymes Inc. , Novozymes A/S
Inventor： Suzanne Otani , Debbie Yaver , Haiyan Ge , Janine Lin , Christopher Amolo , Kim Borch , Shamkant Anant Patkar , Michael Lamsa , Barbara Cherry
IPC: C12N9/20
CPC classification number: C12N9/20 , C12Y301/01003
Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
Abstract translation: 本发明涉及具有脂肪酶活性的分离的多肽和编码多肽的分离的多核苷酸。 本发明还涉及包含多核苷酸的核酸构建体，载体和宿主细胞以及生产和使用多肽的方法。
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Patent Agency Ranking
2.发明申请公开(公告)号：US20130123163A1
公开(公告)日：2013-05-16
申请号：US13747184
申请日：2013-01-22
Applicant: Novozymes, Inc. , Novozymes A/S
Inventor： Suzanne Otani , Debbie Yaver , Haiyan Ge , Janine Lin , Christopher Amolo , Kim Borch , Shamkant Anant Patkar , Michael Lamsa , Barbara Cherry
IPC: C12N9/20
CPC classification number: C12N9/20 , C12Y301/01003
Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
Abstract translation: 本发明涉及具有脂肪酶活性的分离的多肽和编码多肽的分离的多核苷酸。 本发明还涉及包含多核苷酸的核酸构建体，载体和宿主细胞以及生产和使用多肽的方法。
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公开(公告)号：US20190185847A1
公开(公告)日：2019-06-20
申请号：US16309651
申请日：2017-07-05
Applicant: Novozymes A/S
Inventor： Michael Dolberg Rasmussen , Poul Erik Pedersen , Carsten Hjort , Barbara Cherry
CPC classification number: C12N15/11 , C12N9/22 , C12N15/75 , C12N2310/20 , C12N2800/80
Abstract: The present invention relates to methods for improving at least one property of a microorganism host cell by repressing the expression of one or more genome target sequence of interest by CRISPR-inhibition as well as the resulting host cells and methods of production emplying said host cells.
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公开(公告)号：US20160115490A1
公开(公告)日：2016-04-28
申请号：US14890023
申请日：2014-06-18
Applicant: Novozymes A/S
Inventor： Barbara Cherry , Randy Berka
Abstract: Provided herein are Bacillus mutants having improved transformation efficiency, comprising a disruption of an endogenous epsA-O operon. Also described are methods for producing the mutants, methods for generating transformants using the mutants, and methods for producing a polypeptide or fermentation product using the mutants.
Abstract translation: 本文提供具有改善的转化效率的芽孢杆菌突变体，其包含内源性εA-O操纵子的破坏。 还描述了用于产生突变体的方法，使用突变体产生转化体的方法，以及使用突变体产生多肽或发酵产物的方法。
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公开(公告)号：US20190024123A1
公开(公告)日：2019-01-24
申请号：US16065950
申请日：2017-01-06
Applicant: Novozymes A/S
Inventor： Randy Berka , Barbara Cherry
Abstract: The present invention relates to methods for modifying the genome of a Bacillus host cell by employing a Class II Cas9 enzyme with only one active nuclease domain, e.g. the S. pyogenes Cas9 nickase, together with a suitable guide RNA for each target sequence to generate a site-specific nick in at least one genome target sequence followed by the repair of the nick(s) via integration of one or more modified modified donor part of the Bacillus host cell genome through classical double homologous recombination on each side of the nick(s).
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公开(公告)号：US09303248B2
公开(公告)日：2016-04-05
申请号：US13747184
申请日：2013-01-22
Applicant: Novozymes, Inc. , Novozymes A/S
Inventor： Suzanne Otani , Debbie Yaver , Haiyan Ge , Janine Lin , Christopher Amolo , Kim Borch , Shamkant Anant Patkar , Michael Lamsa , Barbara Cherry
IPC: C12N9/20
CPC classification number: C12N9/20 , C12Y301/01003
Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
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