公开(公告)号：US20160168547A1

公开(公告)日：2016-06-16

申请号：US15051169

申请日：2016-02-23

申请人： Novozymes Inc. ,  Novozymes A/S

发明人： Suzanne Otani ,  Debbie Yaver ,  Haiyan Ge ,  Janine Lin ,  Christopher Amolo ,  Kim Borch ,  Shamkant Anant Patkar ,  Michael Lamsa ,  Barbara Cherry

IPC分类号： C12N9/20

CPC分类号： C12N9/20 ,  C12Y301/01003

摘要： The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

摘要翻译： 本发明涉及具有脂肪酶活性的分离的多肽和编码多肽的分离的多核苷酸。 本发明还涉及包含多核苷酸的核酸构建体，载体和宿主细胞以及生产和使用多肽的方法。

公开(公告)号：US08563286B2

公开(公告)日：2013-10-22

申请号：US13762135

申请日：2013-02-07

申请人： Novozymes, Inc. ,  Novozymes A/S

发明人： Debbie Yaver ,  Janine Lin ,  Michael Lamsa ,  Kim Borch ,  Shamkant Anant Patkar

IPC分类号： C12N9/10 ,  C12N15/00 ,  C12N1/20 ,  C07H21/04

CPC分类号： C12N9/20

摘要： The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

公开(公告)号：US20130152234A1

公开(公告)日：2013-06-13

申请号：US13762135

申请日：2013-02-07

申请人： Novozymes, Inc. ,  Novozymes A/S

发明人： Debbie Yaver ,  Janine Lin ,  Michael Lamsa ,  Kim Borch ,  Shamkant Anant Patkar

IPC分类号： C12N9/20

CPC分类号： C12N9/20

摘要： The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

公开(公告)号：US20130123163A1

公开(公告)日：2013-05-16

申请号：US13747184

申请日：2013-01-22

申请人： Novozymes, Inc. ,  Novozymes A/S

发明人： Suzanne Otani ,  Debbie Yaver ,  Haiyan Ge ,  Janine Lin ,  Christopher Amolo ,  Kim Borch ,  Shamkant Anant Patkar ,  Michael Lamsa ,  Barbara Cherry

IPC分类号： C12N9/20

CPC分类号： C12N9/20 ,  C12Y301/01003

摘要： The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

摘要翻译： 本发明涉及具有脂肪酶活性的分离的多肽和编码多肽的分离的多核苷酸。 本发明还涉及包含多核苷酸的核酸构建体，载体和宿主细胞以及生产和使用多肽的方法。

公开(公告)号：US09303248B2

公开(公告)日：2016-04-05

申请号：US13747184

申请日：2013-01-22

申请人： Novozymes, Inc. ,  Novozymes A/S

发明人： Suzanne Otani ,  Debbie Yaver ,  Haiyan Ge ,  Janine Lin ,  Christopher Amolo ,  Kim Borch ,  Shamkant Anant Patkar ,  Michael Lamsa ,  Barbara Cherry

IPC分类号： C12N9/20

CPC分类号： C12N9/20 ,  C12Y301/01003

摘要： The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

公开(公告)号：US20130157325A1

公开(公告)日：2013-06-20

申请号：US13761633

申请日：2013-02-07

申请人： NOVOZYMES A/S

发明人： Leonardo De Maria ,  Jesper Brask ,  Michael Skjot ,  Shamkant Anant Patkar ,  Kim Borch ,  Allan Svendsen

IPC分类号： C12N9/20 ,  C12P7/40 ,  C12P7/64 ,  C12P7/62

CPC分类号： C12N9/20 ,  C12P7/40 ,  C12P7/62 ,  C12P7/6418 ,  C12Y301/01003

摘要： Molecular dynamics (MD) simulation on the three-dimensional structure of Candida anrtarctica lipase B revealed two hitherto unknown lids with a marked mobility, and this discovery was used to design lipolytic enzyme variants with increased lipolytic enzyme activity.

摘要翻译： 针对念珠菌脂肪酶B的三维结构的分子动力学（MD）模拟显示两个具有明显迁移率的未知盖，并且该发现用于设计具有增加的脂肪分解酶活性的脂肪分解酶变体。